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Organic Astragalus Root Extract

Also known as: Astragalus membranaceus, Huangqi, Astragalus Root

Overview

Astragalus membranaceus, commonly known as Huangqi, is a plant native to China and Mongolia. It is a staple in Traditional Chinese Medicine (TCM) and is gaining recognition as a dietary supplement. Astragalus contains polysaccharides, saponins, and flavonoids, which are believed to contribute to its health benefits. It is primarily used for immune system support, cardiovascular health, and as an adjunct therapy in cancer treatment. Research suggests that astragalus may enhance immune function, improve tumor response rates when combined with chemotherapy, and support cardiovascular health by improving left ventricular remodeling in heart failure patients. It is available in various forms, including capsules, extracts, and powders, derived from the root of the plant. The quality of evidence supporting its benefits varies, but systematic reviews and meta-analyses provide insights into its efficacy.

Benefits

Astragalus supplementation has shown several evidence-based benefits. It enhances post-exercise immune functions and improves aerobic performance in athletes. Meta-analyses indicate that astragalus-based herbal formulas, when combined with chemotherapy, may improve tumor response rates. Additionally, astragalus may improve left ventricular remodeling in heart failure patients when used alongside conventional treatment. Studies also suggest that astragalus-containing Chinese herbal medicine (CHM) can reduce serum creatinine and blood urea nitrogen levels when used with Western medicine, indicating potential benefits for kidney function. Significant improvements in SLEDAI scores and reduced adverse events have been observed in patients with systemic lupus erythematosus (SLE) using astragalus-containing CHM. These benefits are typically observed within weeks to months of consistent use.

How it works

Astragalus is believed to exert its effects through several biological pathways. It modulates immune responses by influencing immune cell function and cytokine production. Its antioxidant activity helps protect cells from damage caused by free radicals. In the cardiovascular system, astragalus may improve heart function and reduce inflammation. The bioactive compounds in astragalus, particularly polysaccharides, are thought to be responsible for these effects. While the exact mechanisms are still being investigated, astragalus interacts with the immune, cardiovascular, and possibly the renal systems to promote overall health. The bioavailability of astragalus compounds varies, but oral administration is a common and effective method of delivery.

Side effects

Astragalus is generally considered safe when used appropriately, but some side effects and precautions should be considered. Common side effects are rarely reported but may include mild gastrointestinal symptoms. Due to limited data, uncommon and rare side effects are not well-documented. Potential drug interactions exist, particularly with immunosuppressants or blood thinners, so caution is advised when combining astragalus with these medications. Astragalus is contraindicated during pregnancy and breastfeeding due to insufficient safety data. Individuals with autoimmune diseases should use astragalus with caution, as it may stimulate the immune system. It is essential to consult with a healthcare provider before starting astragalus, especially if you have underlying health conditions or are taking other medications.

Dosage

The minimum effective dose of astragalus is not well-established, but typical dosages range from 500 mg to 2 grams per day. The optimal dosage varies based on individual health goals and is often used in combination with other herbs in TCM. The maximum safe dose is not well-defined, and high doses may increase the risk of side effects. Consistent daily use is common for achieving desired benefits. Astragalus is typically available in oral capsules or extracts. Bioavailability may be enhanced with certain preparation methods, such as specific extraction techniques. No specific cofactors are required for astragalus to be effective. It is advisable to start with a lower dose and gradually increase as needed, while monitoring for any adverse effects.

FAQs

Is astragalus safe to use?

Astragalus is generally safe, but consult a healthcare provider before use, especially if you have underlying health conditions or are taking medications like immunosuppressants or blood thinners.

How should I take astragalus?

Consistent daily use is recommended. It is available in capsules or extracts. Follow the dosage guidelines provided by your healthcare provider or the product label.

What results can I expect from taking astragalus?

Benefits vary based on individual health status and specific use. Some may experience improved immune function, while others may see cardiovascular or kidney health benefits. It is not a cure-all and should be used under medical guidance.

Are there any misconceptions about astragalus?

Yes, astragalus is not a cure-all. It should be used as a complementary therapy under the guidance of a healthcare professional, not as a replacement for conventional medical treatments.

Research Sources

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1395844/full – This meta-analysis of Astragalus-containing Chinese herbal medicine (CHM) used alongside Western medicine showed significant improvements in SLEDAI scores and reduced adverse events in patients with systemic lupus erythematosus (SLE). The study included 800 patients and found that Astragalus-containing CHM improved outcomes when used in conjunction with conventional treatments, highlighting its potential as an adjunct therapy for SLE.
https://www.mdpi.com/2673-8392/4/1/14 – This systematic review on Astragalus membranaceus supplementation in sports found positive impacts on aerobic performance and immune function in athletes. The review analyzed multiple studies and concluded that astragalus can enhance both aerobic capacity and immune response in athletes, suggesting its potential as a natural performance enhancer and immune support supplement.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6700271/ – This meta-analysis indicated that Astragalus-based herbal formulas combined with chemotherapy improve tumor response rates in cancer patients. The study, involving 1,409 patients, found that the addition of astragalus to chemotherapy regimens resulted in improved tumor response rates, suggesting that astragalus may enhance the efficacy of cancer treatment.
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1345797/full – This research article investigates the effects of Astragalus on cardiovascular health, particularly its ability to improve left ventricular remodeling in heart failure patients when combined with conventional treatment. The study suggests that Astragalus may have a beneficial role in supporting heart function and improving outcomes for individuals with heart failure.
https://onlinelibrary.wiley.com/doi/10.1155/2013/426207 – This study examines the effects of Astragalus-containing Chinese herbal medicine (CHM) on kidney function, specifically its ability to reduce serum creatinine and blood urea nitrogen levels when used alongside Western medicine. The findings suggest that Astragalus may have a protective effect on kidney function and could be a valuable adjunct therapy for individuals with kidney-related conditions.