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Sensoril Ashwagandha Root And Leaf Extract

Also known as: Sensoril, Indian ginseng, Winter cherry, Ashwagandha root extract, Ashwagandha leaf extract, Withania somnifera

Overview

Ashwagandha (*Withania somnifera*) is a celebrated adaptogenic herb widely used in Ayurvedic medicine and found chiefly in India, the Middle East, and parts of Africa. This herb is renowned for its capability to alleviate stress and anxiety, along with applications to improve sleep quality, enhance physical performance, and boost overall vitality. It is believed to modulate the hypothalamic-pituitary-adrenal (HPA) axis, a key player in the body's stress response. Clinical investigations underscore a broad range of health benefits associated with ashwagandha, although further long-term studies are necessary to comprehensively elucidate its full effects. Sensoril, a specially standardized extract, is highlighted for its consistent bioavailability and efficacy, making it a preferred option in dietary supplementation for health enthusiasts seeking to improve their well-being.

Benefits

Research has documented significant benefits of ashwagandha, notably a 56.5% reduction in anxiety scores based on the Beck Anxiety Inventory compared to psychotherapy alone. Systematic reviews note major reductions in stress levels, enhanced sleep quality, and augmented vitality, especially among individuals with heightened stress. Additionally, ashwagandha supports improved physical performance and elevated testosterone levels, seen in both men and women. Beneficial effects are generally noticeable within eight weeks of consistent use. The available evidence robustly supports ashwagandha as an effective stress management option, especially for populations experiencing elevated stress levels.

How it works

Ashwagandha primarily functions by modulating the HPA axis, which is critical in managing the body's stress responses. It enhances GABAergic activity, a key regulator of anxiety levels. The herb's bioactive components, chiefly withanolides, interact with neurotransmitters and hormones that affect cortisol and serotonin levels. This interaction primarily occurs through targeting GABA receptors, explaining ashwagandha's adaptogenic and anxiolytic properties. Its intricate relationship with neuroendocrine pathways contributes significantly to its diverse health benefits.

Side effects

Ashwagandha is generally well tolerated with adverse effects reported in less than 5% of clinical trial participants, often comparable to placebo. Most reported side effects are mild, with rare adverse effects (under 1%) of significant concern. Caution is advisable for individuals on medications that influence the HPA axis or neuroendocrine function. Pregnant or breastfeeding women should consult a healthcare provider before using ashwagandha. While it is considered safe for most consumers, further research is vital to establish long-term effects and safety across varying dosage levels comprehensively.

Dosage

The minimum effective dosage for standardized ashwagandha extract to alleviate stress is recommended at 125 mg daily. Common dosages typically range from 300 mg to 600 mg per day, ideally split into two doses for enhanced efficacy. While exceptionally high doses up to 12,000 mg have been noted without significant side effects, such doses should only be taken under medical supervision. For optimal absorption, ashwagandha is recommended to be consumed with meals. Standardized extracts like Sensoril are preferred for their reliable bioavailability and consistent efficacy.