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Organic Ocimum Sanctum

Also known as: Ocimum tenuiflorum, Holy Basil, Tulsi, Sacred Basil, Ocimum sanctum

Overview

*Ocimum sanctum*, commonly known as Holy Basil or Tulsi, is an herb native to the Indian subcontinent and Southeast Asia, integral to traditional Ayurvedic medicine. It is celebrated for its wide range of medicinal properties, including antimicrobial, antidiabetic, antioxidant, and adaptogenic effects. Often made into teas, supplements, or used in culinary dishes, this herb contains various phytochemicals such as flavonoids, phenolic acids, and terpenes, which are key to its health benefits. Currently, there is a growing body of research surrounding *Ocimum sanctum*, encompassing in vitro, animal, and human studies, though further large-scale clinical trials are necessary to conclusively establish its efficacy and safety. The variability in study designs and sample sizes contributes to the diverse quality of evidence available, with some systematic reviews and randomized controlled trials demonstrating credible findings.

Benefits

[{"benefit":"Anxiety and Stress Reduction","evidence_strength":"Moderate","description":"A randomized, double-blind, placebo-controlled trial demonstrated a significant reduction in anxiety levels, with 500 mg of leaf extract twice daily reducing Perceived Stress Scale scores by 37% over 8 weeks."},{"benefit":"Antimicrobial Properties","evidence_strength":"High","description":"A systematic review confirmed effective anticandidal properties in vitro, suggesting potential for use against systemic and topical candidal infections."},{"benefit":"Antidiabetic Activity","evidence_strength":"Low to Moderate","description":"Animal studies indicate reduction in blood glucose levels and improvement in lipid profiles following treatment with aqueous root extracts."},{"benefit":"Antioxidant and Adaptogenic Activities","evidence_strength":"Low","description":"Animal studies revealed antioxidant effects and improved physical performance with root extracts."}]

How it works

*Ocimum sanctum* exhibits its effects through multiple biological pathways, including antioxidant and anti-inflammatory mechanisms. It notably influences the hypothalamic-pituitary-adrenal (HPA) axis, crucial for the body’s stress response. The phytochemicals present target specific molecular pathways associated with stress management, glucose metabolism, and immune response, contributing to its adaptogenic and restorative effects.

Side effects

[{"type":"Common Side Effects (greater than 5%)","details":"No significant adverse effects were reported in studies, although general safety is acknowledged."},{"type":"Uncommon Side Effects (1-5%)","details":"Limited documentation available regarding less frequent side effects."},{"type":"Rare Side Effects (less than 1%)","details":"Potential reproductive toxicity observed in animal studies raises concerns, though evidence in humans is not well-studied."}]

Dosage

The recommended dosage for *Ocimum sanctum* is typically in the range of 500 mg to 1 gram per day of leaf extract. A noted effective dose is 500 mg taken twice daily observed in studies focused on anxiety reduction. While no maximum safe dose has been established, caution is warranted if approaching higher dosages. Consistent daily dosing is generally advised, and factors such as extraction form and potential cofactors that may enhance absorption should be considered.

FAQs

Is *Ocimum sanctum* safe for everyone?

While *Ocimum sanctum* is generally safe, pregnant and lactating women should consult healthcare providers due to potential reproductive toxicity.

When is the best time to take *Ocimum sanctum*?

There is no specific timing proven optimal; however, consistent daily dosing is recommended for effectiveness.

What benefits can I expect?

Users may experience reduced stress and anxiety, potential improvements in blood glucose control, and enhanced antioxidant status.

Can I use *Ocimum sanctum* instead of my medication?

It should not be considered a substitute for medical care; consult a healthcare provider for personalized advice.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/35677004/ – This systematic review highlights the effective anticandidal properties of *Ocimum sanctum*, based on various in vitro studies. It adheres to PRISMA criteria, reflecting sound methodology despite limitations inherent to in vitro research.
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.965130/full – This randomized, double-blind, placebo-controlled trial establishes significant reductions in anxiety levels among participants using *Ocimum sanctum*. The study design was robust, with a well-defined population and statistical significance.
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2021.765024/full – This animal study explores the antidiabetic effects of *Ocimum sanctum*, revealing its ability to lower blood glucose and improve lipid profiles, indicating a potential therapeutic role, although human validation is still necessary.