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Baliospermum

Also known as: Danti, Red Physic Nut, Baliospermum montanum

Overview

*Baliospermum montanum* is a perennial herb from the Euphorbiaceae family, traditionally used in Ayurvedic medicine for various ailments, including asthma, bronchitis, and functions as a purgative, anthelmintic, diuretic, and tonic. Its primary applications focus on anti-inflammatory and antimicrobial properties, backed by moderate research, most of which centers on in vitro and in vivo studies rather than human trials. Key characteristics include its herbal form and its incorporation into traditional healing practices in Indian medicine. Although it has shown promise in preliminary studies, the overall evidence quality is variable, highlighting a significant need for well-structured clinical research to establish its efficacy and safety as a supplement.

Benefits

Research highlights several potential benefits of *Baliospermum montanum*, especially its anti-inflammatory effects, which have been demonstrated in vitro with an IC50 of 9.08 μg/ml for ethyl acetate extracts inhibiting mitogen-induced PBMC activity. It may provide auxiliary support for individuals with inflammatory conditions; however, the current body of evidence primarily relies on preclinical studies. Additionally, antimicrobial and anthelmintic activities have been noted, but these findings are based on a limited number of studies. Due to the lack of robust clinical trials, the clinical significance of these effects in humans is not well established.

How it works

The anti-inflammatory properties of *Baliospermum montanum* likely arise from the inhibition of inflammatory signaling pathways, although specific molecular targets remain unclear. The herb appears to interact with immune system cells to modulate inflammatory responses. However, detailed mechanisms of action and bioavailability in humans have not been sufficiently studied, limiting understanding of its effective application.

Side effects

Information on the side effects of *Baliospermum montanum* is limited, with overall human safety data being scarce due to the lack of clinical trials. Common side effects are not well-documented, although gastrointestinal disturbances may occur due to its purgative effects. There are no established rare side effects reported, and drug interactions remain unclear. Caution is advised for pregnant or lactating women due to inadequate safety data. Additionally, individuals with sensitive stomachs or allergies to plants in the Euphorbiaceae family should use this supplement cautiously.

Dosage

Specific dosing guidelines for *Baliospermum montanum* in humans are not well-defined, as traditional uses are primarily based on decoctions or extracts without standardized dosages. The minimum effective dose remains unspecified, and the maximum safe dose has not been established. Timing considerations for administration are also not well-researched, nor are absorption factors well understood. Traditionally, it is used in crude extract or decoction forms, but precise dosing is recommended only under healthcare supervision.

FAQs

What should I know before using Baliospermum montanum?

Consult a healthcare provider before use, especially for medical conditions, due to limited safety and efficacy data.

Is it safe to take Baliospermum montanum?

Safety data on humans is lacking, thus caution is advised before use, particularly for sensitive populations.

When is the best time to take Baliospermum montanum?

Timing and administration are not well-established; follow healthcare provider recommendations.

What results can I expect from using Baliospermum montanum?

Potential anti-inflammatory effects may be observed, but there is a significant lack of evidence in human studies.

Are there misconceptions about Baliospermum montanum?

Many believe in its efficacy without robust clinical evidence; it's crucial to approach with caution.

Research Sources

https://www.ajol.info/index.php/ajb/article/download/135788/125285 – This study reports the anti-inflammatory properties of ethyl acetate extracts of *Baliospermum montanum*, highlighting significant in vitro activity but emphasizing the need for clinical validation.
https://li01.tci-thaijo.org/index.php/sehs/article/download/242850/172109/888751 – The phytochemical analysis indicates the presence of various bioactive compounds in *Baliospermum montanum*, yet clinical implications remain unexplored.
https://www.researchgate.net/publication/238343890_Free_radical_scavenging_activity_of_aqueous_extract_of_roots_of_Baliospermum_montanum_Muell-Arg – Investigated the free radical scavenging activity of aqueous extracts, offering insights into the antioxidant properties but lacking clinical relevance.
https://www.clinicalkey.fr – A comprehensive database providing relevant literature, though specific systematic reviews involving *Baliospermum montanum* remain absent.
https://www.researchgate.net/publication/285785722_Phytochemical_analysis_and_free_radical_scavenging_potential_of_Baliospermum_montanum_Willd_Muell_leaf – This study delves into the phytochemical content and antioxidant potential but does not connect findings to clinical applications.