ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Simply Immune

Simply Immune

NutriCology

#Other
68
Safety80
Efficacy55
Transparency62
Based on Examine, Wikipedia, and 23 other sources

Overview

Simply Immune contains a proprietary blend of mushroom and plant polysaccharides, primarily Natramune, which includes several ingredients known for their immunomodulatory properties. While individual components like Reishi, Shiitake, and Maitake have extensive research supporting their immune-boosting effects, the proprietary nature of the blend and the lack of specific dosages for each ingredient make it difficult to ascertain the full efficacy of the product. The 500mg total per serving for a complex blend suggests potential underdosing for some of the more well-researched components to reach their optimal therapeutic effects.

The Good

Features several well-researched immune-supporting mushrooms (Reishi, Shiitake, Maitake)

Includes plant-derived polysaccharides (arabinogalactans, arabinoxylans) with prebiotic benefits

Ingredients have broad immunomodulatory actions, supporting balanced immune responses

The Bad

Proprietary blend (Natramune) obscures individual ingredient dosages, hindering efficacy assessment

Total blend dose (500mg) is relatively low, suggesting some key ingredients may be underdosed for optimal benefit

Lack of specific clinical trials on the 'Natramune' blend itself

Is it for you?

Best For: Individuals seeking general immune system support

Skip If: You have specific allergies to common immune support ingredients or are on medication without consulting a healthcare professional.

Ingredients Analysis

Natramune Mushroom Polysaccharide Complex Proprietary Blend

500 mg

How to Use

Follow dosage instructions on the product label, typically taken with water or food.

Frequency:

Daily

Best Time:

Anytime

When:

With food

Who Should Use This

Best For:

Individuals seeking general immune system support

Similar Products

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement by Vetriscience®

Vetri-Science® Laboratories Healthymouth™ Natural Zeolites for Dogs & Cats Dental Health Supplement

Vetriscience®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT by GNARLY®

COLLAGEN PRO Pasture Raised Peptides UNFLAVORED DIETARY SUPPLEMENT

GNARLY®

Muscle memory Creatine Powder supplement by Ora®

Muscle memory Creatine Powder supplement

Ora®

Amazing Formulas MSM (Methylsulfonylmethane) Supplement by Amazing Nutrition

Amazing Formulas MSM (Methylsulfonylmethane) Supplement

Amazing Nutrition

Fiber GDX Dietary Supplement Fiber / Orange Flavor by THE PAUSENUTRITION®

Fiber GDX Dietary Supplement Fiber / Orange Flavor

THE PAUSENUTRITION®

PROSTATE HEALTH SUPPLEMENT by OFFSTATE

PROSTATE HEALTH SUPPLEMENT

OFFSTATE

Recommended Articles

Glutamine Dosage for Gut Health: A Guide

Glutamine Dosage for Gut Health: A Guide

Glutamine supports gut health with a recommended dosage of 5-30 grams per day, available in various supplement forms.

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal supplements may interact with COVID-19 antivirals, requiring careful consideration and further research.

2025's Top Vegan Protein Powders: A Buyer's Guide

2025's Top Vegan Protein Powders: A Buyer's Guide

In 2025, the best vegan protein powders are third-party tested, ensuring purity, safety, and high nutritional content.

Top Ingredients for Healthy Weight Management

Top Ingredients for Healthy Weight Management

Dietary fiber, protein, omega-3 fatty acids, and water are crucial for managing a healthy weight.