ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Petadolex

Petadolex

Integrative Therapeutics

#Other
82
Safety91
Efficacy72
Transparency68
Based on Examine, Wikipedia, and 23 other sources

Overview

Petadolex, containing PA-free butterbur extract standardized to petasins, is effective for migraine prevention based on clinical research. The dosing aligns with studies showing significant reductions in migraine frequency. The inclusion of free petasins further strengthens its potential efficacy.

The Good

PA-Free Formulation: Significantly reduces the risk of liver toxicity, a major concern with other butterbur products.

Clinically Supported for Migraine Prevention: Studies show butterbur extract can effectively reduce migraine frequency.

Standardized to Petasins: Ensures consistent levels of the active compounds responsible for therapeutic effects.

The Bad

Requires Multiple Doses Daily: Three softgels per day may be inconvenient for some users.

Potential for Mild Gastrointestinal Side Effects: Such as burping, which is common with butterbur extracts.

Specific Liver Warnings: Despite being PA-free, individuals with liver disorders or those who develop liver symptoms should avoid or discontinue use.

Is it for you?

Best For: Individuals seeking natural migraine relief, those concerned about liver safety with butterbur

Skip If: You have pre-existing health conditions or are taking other medications without consulting a healthcare provider.

Ingredients Analysis

Purple Butterbur Root Extract

50 mg

Petasins

7.5 mg

How to Use

Take as directed by a healthcare professional, typically daily for migraine prevention.

Frequency:

Daily

Best Time:

Morning or as directed

When:

With or without food

Who Should Use This

Best For:

Individuals seeking natural migraine relief, those concerned about liver safety with butterbur