

Long Dan Xie Gan Wan
Min Shan
Overview
Long Dan Xie Gan Wan is a well-established Traditional Chinese Medicine formula with a long history of use. While individual ingredients have supporting research for anti-inflammatory, hepatoprotective, and diuretic effects, the efficacy of the complete formula often relies on historical use and synergistic actions within TCM principles, rather than double-blind placebo-controlled trials on the entire blend. The inclusion of a proprietary blend without disclosed individual ingredient amounts makes it difficult to assess precise dosing of each component for modern scientific validation.
The Good
Traditional Efficacy: Long Dan Xie Gan Wan is a classic TCM formula with centuries of use for specific patterns of imbalance.
Comprehensive Formula: Addresses multiple aspects of 'damp-heat' and 'fire' symptoms through a synergistic blend of herbs.
Anti-inflammatory and Hepatoprotective Properties: Contains ingredients like Gentiana scabra and Scutellaria baicalensis, which have research supporting these effects.
The Bad
Proprietary Blend: The use of a 'Proprietary Extract Blend' obscures the specific quantities of each ingredient, making it impossible to ascertain if individual herbs are dosed effectively based on modern research.
Potential Toxicity Concerns with Akebia: Historically, some Akebia species have been adulterated with Aristolochia, which is nephrotoxic. While reputable manufacturers aim to prevent this, the ingredient itself prompts caution.
Licorice Side Effects: Glycyrrhiza uralensis (licorice) can cause elevated blood pressure and fluid retention, especially with high or prolonged use.
Is it for you?
Best For: Individuals with TCM patterns of Liver/Gallbladder damp-heat or fire, under professional guidance.
Skip If: You are pregnant, nursing, have a chronic illness, or are taking medications without consulting a practitioner.
Ingredients Analysis
Proprietary Extract Blend
1320 mgHow to Use
Typically 8 pills, 3 times daily, or as directed by a healthcare practitioner.
Daily
Morning & Evening
Between meals or with food
Who Should Use This
Best For:
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