Fibrinex
HoltraCeuticals
Overview
Fibrinex combines several proteolytic enzymes that may support normal coagulation and reduce inflammation. Bromelain and nattokinase are dosed reasonably well and supported by research, while lumbrokinase, serratiopeptidase, and alpha-chymotrypsin have less robust evidence. The supplement may offer synergistic benefits, but more research is necessary to validate its overall effectiveness.
The Good
Contains Bromelain at Clinically Relevant Dose: The 500mg dose of bromelain is within the range shown to be effective for reducing pain and inflammation.
Includes Nattokinase which Has Proven Blood Pressure Benefits: Nattokinase has been shown to significantly reduce systolic and diastolic blood pressure.
May Support Normal Coagulation: The combination of enzymes may synergistically support healthy coagulation.
The Bad
Potential Interactions with Anticoagulants: Nattokinase, lumbrokinase, and alpha-chymotrypsin may interact with anticoagulant medications, increasing the risk of bleeding.
Insufficient Long-Term Safety Data: Long-term safety data is lacking for most ingredients, especially lumbrokinase and serratiopeptidase.
Gastrointestinal Side Effects: Some individuals may experience gastrointestinal disturbances such as nausea or flatulence due to bromelain and other enzymes.
Is it for you?
Best For: Individuals seeking targeted support for a specific physiological function (e.g., fibrinolysis, gut health), as determined by ingredients.
Skip If: You are pregnant, nursing, or have pre-existing medical conditions without consulting a healthcare professional.
Ingredients Analysis
How to Use
Take as directed on the product label, likely with water.
Daily
Morning
With food
Who Should Use This
Best For:
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