Zhuling Mushroom
Also known as: *Grifola umbellata*, Zhuling mushroom, Umbrella polypore, *Polyporus umbellatus*
Overview
Zhuling mushroom, scientifically known as *Polyporus umbellatus*, is a medicinal fungus that grows in clusters at the base of trees, predominantly in Asia. Recognized for its umbrella-like appearance, this mushroom is traditionally utilized in Chinese medicine for its potential health benefits. Among its primary uses are immune system support and potential anti-tumor properties. The mushroom boasts a variety of bioactive compounds, including polysaccharides, triterpenoids, and phenolic compounds, which are believed to contribute to its health benefits. Although there is a long-standing tradition of use and some preliminary clinical research, the evidence is not as extensive compared to other medicinal mushrooms, requiring further rigorous studies to establish its efficacy and safety.
Benefits
Zhuling mushroom is noted for several potential health benefits, particularly in immune system support and anti-tumor activity. Evidence from studies indicates that the polysaccharides in *Polyporus umbellatus* may enhance immune cell function and cytokine production, potentially benefiting cancer patients, especially during chemotherapy. Additionally, some evidence suggests antioxidant properties. However, the clinical significance and effect sizes remain under-researched, necessitating more extensive studies to quantify these effects and define optimal populations for benefit.
How it works
The health benefits of *Polyporus umbellatus* are primarily attributed to its bioactive compounds, particularly polysaccharides that interact with the immune system. These compounds enhance immune cell activity, including monocytes and natural killer cells, and influence critical signaling pathways involved in cell death and tumor growth inhibition, suggesting multiple mechanisms of action against tumors and immune modulation.
Side effects
While *Polyporus umbellatus* is traditionally considered safe, modern safety evaluations are limited. Commonly reported side effects from similar medicinal mushrooms include mild gastrointestinal symptoms. There are no specific data on rare or uncommon side effects, and no documented drug interactions exist, but caution is advised for individuals on medications or with compromised immune systems, particularly for those undergoing chemotherapy. Consulting with healthcare practitioners before use is recommended, especially for pregnant or nursing individuals.
Dosage
*Polyporus umbellatus* does not have an established minimum effective dose. Traditional dosing practices and studies on similar mushrooms advise usage ranging from 1-10 grams of dried mushroom per day, although optimal dosages remain undefined. High doses are discouraged without medical supervision. The mushroom can be consumed in various forms (dried, powdered, extracts), with absorption potentially varying by form. There is no specific guidance on absorption cofactors or required timing for maximal effectiveness.
FAQs
Is *Polyporus umbellatus* safe to take?
While traditionally used, modern safety evaluations are limited; consult a healthcare practitioner before use.
How should I take Zhuling mushroom?
There are no specific guidelines for timing, but daily consumption is generally recommended.
What results can I expect?
Potential benefits include immune support and anti-tumor effects, though definitive research is still needed.
Are all medicinal mushrooms the same?
No, each medicinal mushroom has unique effects and safety profiles; thus, they should not be generalized.
Research Sources
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1147641/full – This systematic review highlights the immunomodulatory effects of polysaccharides from medicinal mushrooms, including similarities to *Polyporus umbellatus*, suggesting potential anti-tumor and immune-enhancing benefits. Limited specific findings on *Polyporus umbellatus* necessitate further focused research.
- https://pubmed.ncbi.nlm.nih.gov/28267567/ – This safety assessment review emphasizes the limited modern evaluations of medicinal mushrooms, building a case for a weight-of-evidence approach when assessing their safety, including mushrooms like *Polyporus umbellatus*, which lacks specific data.
- https://www.drfuhrman.com/content-image.ashx/e45dkuborf3unpu8j01943/Complete-Greens-Fact-Sheet-240404.pdf – This fact sheet includes various health aspects of popular dietary mushrooms, emphasizing their bioactive compounds and potential health benefits. However, specific details on *Polyporus umbellatus* were minimal.
- https://pubmed.ncbi.nlm.nih.gov/21793723/ – The study discusses the immunomodulatory functions and potential anti-tumor mechanisms of natural polysaccharides in medicinal mushrooms, although it lacks direct evidence for *Polyporus umbellatus*.
- https://onlinelibrary.wiley.com/doi/abs/10.1155/2014/925069 – This systematic review reviews the anti-tumor properties of natural polysaccharides from various sources, indicating ways in which mushrooms might inhibit tumor growth, echoing the need for more studies on specific mushrooms such as *Polyporus umbellatus*.
Supplements Containing Zhuling Mushroom
Recommended Articles

Best Ingredients for Healthy Hair Growth
Vitamins D, iron, zinc, and natural oils like rosemary are crucial for healthy hair growth.

Mushroom Supplement Extraction: Enhancing Potency
Extraction is essential to unlock the full potency of certain mushroom supplements like Reishi, Cordyceps, and Lion's Mane.

Vitamin D2 vs D3: Optimal Doses & Benefits
Vitamin D3 is more effective than D2 in raising vitamin D blood levels, with recommended doses varying based on individual needs.

Top Adaptogens for Stress Relief: A Scientific Guide
Adaptogens like Ashwagandha, Rhodiola, and Holy Basil are effective for stress relief, supported by clinical evidence.