Total Cbd
Also known as: CBD, Cannabidiol, Cannabidiol (CBD)
Overview
Cannabidiol (CBD) is a non-psychoactive compound derived from the cannabis plant, primarily found in hemp. It has garnered attention for its potential therapeutic benefits, including alleviating pain, reducing anxiety, and improving sleep quality. CBD does not induce the 'high' commonly associated with cannabis use. Research on CBD is moderate, with numerous studies indicating promising benefits, although often hindered by small sample sizes and inconsistent methodologies. CBD is available in various forms, including oils, capsules, and topical applications, making it a versatile supplement for users seeking alternative therapies.
Benefits
CBD has shown evidence in reducing anxiety and stress levels, improving sleep quality, and alleviating various pain types. Specific studies indicate that CBD may lower blood pressure and heart rate under stress, promote cerebral blood flow, and provide potential benefits for insomnia, particularly when combined with THC. However, the clinical significance remains under inquiry, given that many studies are limited in scale and rigor. Existing data suggest a dosage of around 25 mg to 100 mg may be effective for anxiety and sleep disturbances, although individual responses vary widely.
How it works
CBD's mechanism of action primarily involves interacting with the endocannabinoid system, influencing pain perception and regulating mood. It modulates receptors such as CB1 and CB2 indirectly and impacts other targets like TRPV1, pivotal in regulating various body functions. Additionally, CBD affects the nervous and cardiovascular systems and may influence immune responses, contributing to its therapeutic potential.
Side effects
Generally regarded as safe, CBD can cause several side effects, including fatigue, changes in appetite, and diarrhea. Less commonly, users may experience dizziness, nausea, or elevated liver enzymes. Special care should be taken when considering CBD alongside medications metabolized by CYP450 enzymes, as interactions may occur. Pregnant and breastfeeding individuals should avoid CBD due to insufficient safety data. Caution is advised for those with liver conditions and children, as the long-term effects of CBD use are not fully established.
Dosage
The effective dose of CBD varies based on individual needs and the specific condition being treated, generally starting around 25 mg per day for anxiety and sleep. Optimal dosages are often in the range of 25 to 100 mg daily, although caution is advised beyond 200 mg due to limited understanding of safety thresholds. CBD can be taken orally, sublingually, or applied topically, with bioavailability varying significantly across different administration methods. For best results, CBD is often recommended to be taken before bedtime for sleep effects.
FAQs
What should I consider when using CBD?
Start with a low dose and observe effects; consult a healthcare provider for possible interactions.
Is CBD safe to use?
CBD is generally considered safe, but individuals should monitor for side effects and drug interactions.
When is the best time to take CBD?
For sleep, it is best taken before bedtime; for anxiety, it should be used as needed.
How long does it take to feel effects from CBD?
Effects may vary; some users could take several days to notice changes.
Does CBD make you high?
No, CBD is non-psychoactive and does not produce a 'high' associated with THC.
Research Sources
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00081/full – This systematic review indicates that CBD may reduce blood pressure and heart rate during stressful situations, although these effects are not observed in normal conditions, highlighting the need for more comprehensive human studies.
- https://pubmed.ncbi.nlm.nih.gov/36149724/ – A systematic review assessing the effects of CBD on insomnia suggests it may be beneficial, particularly when paired with THC, though many studies did not utilize objective measures and lacked direct focus on insomnia.
- https://jamanetwork.com/journals/jama/fullarticle/2338251 – This systematic review and meta-analysis reported that cannabinoids, including CBD, could help manage pain and other medical conditions; however, clinical heterogeneity and varied outcomes were observed among studies.
Supplements Containing Total Cbd
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