tetra sodium iminodisuccinate
Also known as: Tetrasodium iminodisuccinate, S,S-, Iminodisuccinic acid, S,S-, tetrasodium salt, L-Aspartic acid, N-((1S)-1,2-dicarboxyethyl)-[2], Tetrasodium iminodisuccinate
Overview
Tetrasodium iminodisuccinate (IDS) is a chelating agent derived from bio-based maleic anhydride and is known for its biodegradability. Its primary application lies in environmental contexts, particularly in water treatment, where it effectively binds metal ions like Cu2+. This characteristic also makes it useful in spectrophotometric determination of copper. While IDS is being explored for cosmetic formulations due to its chelating properties and perceived safety, its use as a direct health supplement is not well-researched. The available evidence primarily stems from environmental and safety studies, with limited clinical trials investigating its potential health benefits in humans. Therefore, its role and efficacy as a dietary supplement remain largely undefined.
Benefits
Currently, there is no direct evidence to support the use of tetrasodium iminodisuccinate (IDS) as a health supplement. Its benefits are primarily observed in environmental applications, where it acts as a chelating agent. No documented health benefits, such as improvements in specific conditions or outcomes, exist in the context of human supplementation. Therefore, no population-specific benefits, effect sizes, or clinical significance can be determined based on the available research. Further studies would be needed to explore any potential health-related effects.
How it works
Tetrasodium iminodisuccinate (IDS) functions primarily as a chelating agent. Its mechanism of action involves binding to metal ions, such as Cu2+, through coordination bonds. This chelation process is particularly useful in environmental applications like water treatment, where IDS can help remove heavy metals from solutions. There is no documented evidence of IDS interacting with specific body systems or molecular targets in the context of human supplementation, as its use in this area is not well-established.
Side effects
Tetrasodium iminodisuccinate (IDS) is generally considered safe for use in cosmetic formulations, with studies indicating no genotoxic effects. However, comprehensive data on its safety profile as a dietary supplement in humans is lacking. As such, common, uncommon, and rare side effects are not documented in the context of human consumption. Drug interactions and contraindications have not been studied. While animal studies have used doses up to 1500 mg/kg bw without significant adverse effects, this does not directly translate to human safety. More research is needed to fully understand the potential adverse effects of IDS when ingested.
Dosage
Due to the lack of research on tetrasodium iminodisuccinate (IDS) as a dietary supplement, minimum effective doses, optimal dosage ranges, and maximum safe doses have not been established for human consumption. Timing considerations, form-specific recommendations, absorption factors, and required cofactors are also not applicable in this context. While animal studies have explored high doses without significant adverse effects, these findings cannot be directly extrapolated to humans. Therefore, specific dosing guidelines for IDS as a supplement cannot be provided based on the current available evidence.
FAQs
Is tetrasodium iminodisuccinate safe to consume?
IDS is considered safe for cosmetic use, but its safety as a dietary supplement is not well-established. More research is needed to determine its safety profile when ingested.
What are the health benefits of taking IDS?
Currently, there is no evidence to support any health benefits from taking IDS as a supplement. Its primary applications are in environmental contexts.
How is IDS typically used?
IDS is primarily used as a chelating agent in environmental applications, such as water treatment, and is being explored for use in cosmetic formulations.
Are there any known side effects from taking IDS?
Side effects from ingesting IDS are not well-documented due to the lack of research on its use as a dietary supplement. Caution is advised until more data is available.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10386959/ – This study explores the use of tetrasodium iminodisuccinate (IDS) as a ligand for Cu2+ in water solutions. The research indicates that IDS has potential applications in water treatment processes due to its ability to effectively bind copper ions, which is crucial for removing heavy metals from contaminated water sources.
- https://pubchem.ncbi.nlm.nih.gov/compound/Tetrasodium-iminodisuccinate_-S_S – This PubChem entry provides chemical and structural information about tetrasodium iminodisuccinate. It serves as a reference for its chemical properties and classification, aiding in understanding its behavior in various applications.
- https://www.industrialchemicals.gov.au/sites/default/files/STD1018%20Public%20Report%20PDF.pdf – This public report assesses the safety of tetrasodium iminodisuccinate for industrial use. The findings contribute to understanding its potential environmental and health impacts, providing a basis for safe handling and application guidelines.
- https://www.cir-safety.org/sites/default/files/SLR_TrisodiumEthylenediamineDisuccinate_062022.pdf – This safety review by the Cosmetic Ingredient Review (CIR) Expert Panel evaluates the safety of trisodium ethylenediamine disuccinate, a related compound. The review helps inform the safety assessment of similar chelating agents in cosmetic formulations, ensuring consumer safety.
- https://www.cir-safety.org/sites/default/files/Trisodium%20Ethylenediamine%20Disuccinate_0.pdf – This document from the Cosmetic Ingredient Review (CIR) provides additional safety data on trisodium ethylenediamine disuccinate. It includes detailed information on its potential for irritation and sensitization, contributing to a comprehensive safety profile for cosmetic applications.