ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Tendopure Proprietary Blend

Also known as: Collagen peptides, Hydrolyzed collagen, Collagen Peptides

Overview

Collagen peptides are bioactive fragments derived from collagen, primarily type I collagen found in connective tissues such as skin, bones, and cartilage. Sourced commonly from animal products, these peptides are used as dietary supplements to support various health aspects, particularly joint health, skin elasticity, and overall connective tissue maintenance. While current research on collagen peptides shows moderate maturity, particularly in their application for joint and skin health, evidence quality varies across studies. As a dietary supplement, collagen peptides are recognized for their bioavailability, allowing them to stimulate collagen synthesis effectively, which has been linked to benefits in joint function and skin health.

Benefits

Collagen peptides have been associated with several evidence-based benefits. Primarily, they may improve joint pain and function among osteoarthritis patients, with some studies reporting significant pain reductions and functional enhancements. For skin health, collagen peptides have been found to increase skin elasticity, hydration, and overall appearance. Secondary benefits also suggest potential improvements in nail and hair health, though the supporting evidence for these is less substantial. Particularly, older adults and individuals suffering from osteoarthritis stand to gain the most from collagen supplementation. Effect sizes vary, with some meta-analyses indicating moderate improvements in joint-related outcomes. Observable benefits typically emerge within several weeks to a few months of consistent use.

How it works

Collagen peptides work primarily by stimulating collagen synthesis within the body. They activate specific collagen receptors and growth factors involved in the production of collagen in cartilage and skin, thereby potentially enhancing joint cartilage health and improving skin elasticity. They exhibit good absorption and bioavailability, allowing efficient delivery into the body’s systems, particularly the musculoskeletal and integumentary systems.

Side effects

Collagen peptides are generally considered safe for consumption, though comprehensive long-term safety data is lacking. Common side effects, occurring in more than 5% of users, may include gastrointestinal discomfort such as bloating and gas. Less frequently, some individuals (1-5%) may experience allergic reactions or mild skin rashes. Severe allergic reactions are rare (<1%), but individuals with allergies to collagen sources should avoid these supplements. There may also be potential interactions with anticoagulants or medications affecting blood pressure. Caution is advised for pregnant or breastfeeding women who should consult healthcare providers before use.

Dosage

The minimum effective dose of collagen peptides typically starts around 5-10 grams per day. An optimal dosage range for those seeking benefits is generally between 10-20 grams daily. While no specific maximum safe dose has been universally established, up to 20 grams is typically considered safe. Collagen peptides are best consumed on an empty stomach or alongside a meal for optimal absorption. Common formulations include powder or capsules. It's suggested that intake of vitamin C may enhance collagen absorption, although no specific cofactors are strictly required.

FAQs

How should I take collagen peptides for the best results?

For optimal effects, ensure consistent daily intake, ideally on an empty stomach or with meals, and stay well-hydrated.

Are there any side effects associated with collagen peptides?

While generally safe, some may experience gastrointestinal upset, and allergic reactions are possible, though rare.

When will I notice results from taking collagen peptides?

Many users report improvements in joint health and skin elasticity within a few weeks of consistent use.

Can collagen peptides cure joint diseases?

No, collagen peptides are not a cure for severe joint diseases; it's essential to consult a healthcare provider for serious conditions.

Do I need to take anything else with collagen supplements?

While no specific cofactors are required, adding vitamin C may enhance collagen absorption.

Research Sources

  • https://www.1mg.com/otc/tendopure-tablet-otc633864 – The research surrounding collagen peptides suggests positive outcomes for joint health, with systematic reviews indicating their effectiveness in reducing pain and improving function for patients with osteoarthritis. Additionally, collagen peptides have been linked to enhanced skin health by increasing elasticity and hydration.

Recommended Articles

Top Fertility Supplements for Women in 2025

Top Fertility Supplements for Women in 2025

By 2025, new FDA-approved fertility supplements, emphasizing organic ingredients, have shown significant effectiveness in aiding conception for women in their 30s.

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-scanner supplement apps vary in accuracy, especially with proprietary blends, but advancements are improving their reliability.

Legal Pre-Workout Supplements for Athletes

Legal Pre-Workout Supplements for Athletes

Legal pre-workout supplements like those with caffeine, beta-alanine, and creatine can safely enhance athletic performance without failing doping tests.

Top Testosterone Boosters for Cyclists: A Buyer's Guide

Top Testosterone Boosters for Cyclists: A Buyer's Guide

For cyclists, choosing testosterone boosters involves finding scientifically-backed, third-party tested products, with top picks including brands like TestoGen and Prime Male.