Tangerine Green Fruit Rind Extract
Also known as: Tangerine Green Fruit Rind Extract, Tangerine Extract, Mandarin Extract, Citrus reticulata, Citrus reticulata Extract
Overview
Tangerine Green Fruit Rind Extract is a dietary supplement derived from the peel of tangerines (*Citrus reticulata*). It is rich in bioactive compounds, particularly polymethoxylated flavones (PMFs) like tangeretin, nobiletin, and sinensetin, as well as flavanone glycosides (FGs). The extract is primarily used for its potential antioxidant, anti-inflammatory, and antimicrobial properties. While *in vitro* and animal studies suggest promising effects, human trials are limited, and the quality of available evidence is still emerging. The extract is generally considered safe, but long-term effects and interactions are not well-documented. Further research is needed to establish its efficacy and safety as a dietary supplement. It is available in various forms, including capsules and powders, and is often marketed for its potential cardiovascular and metabolic benefits.
Benefits
The primary purported benefits of Tangerine Green Fruit Rind Extract are its antioxidant and anti-inflammatory effects, which have been demonstrated mainly in *in vitro* and animal studies. Limited research suggests potential benefits for cardiovascular health and metabolic syndrome, but these findings require confirmation through rigorous human trials. While it may be beneficial for individuals seeking antioxidant supplements, the evidence is not strong enough to support specific health claims. Effect sizes and clinical significance are not well established due to the lack of human trials, and the time course of benefits remains unknown. Studies on related citrus fruits suggest potential benefits for weight management and metabolic health, though these findings are not directly applicable to tangerine extracts.
How it works
Tangerine Green Fruit Rind Extract is believed to exert its effects through antioxidant pathways, potentially influencing inflammation and lipid metabolism. The flavonoids present in the extract may target various enzymes and receptors involved in inflammation and oxidative stress. It may interact with cardiovascular and metabolic systems, though the exact mechanisms are not fully understood. Absorption and bioavailability of the extract in humans are not well studied. The PMFs found in tangerine extract, such as nobiletin and tangeretin, are thought to play a key role in its potential health benefits by modulating gene expression and cellular signaling pathways.
Side effects
The overall safety assessment of Tangerine Green Fruit Rind Extract suggests it is generally considered safe, but long-term effects and interactions are not well documented due to limited human studies. Common side effects are not well established, though potential gastrointestinal upset has been suggested but not documented. Uncommon and rare side effects are currently unknown. There is a potential for interactions with blood thinners or diabetes medications due to the flavonoid content, but these interactions are not well studied. While there are no established contraindications, caution is advised for pregnant or breastfeeding women due to a lack of data. Individuals with allergies to citrus fruits should also exercise caution.
Dosage
Due to limited research, the minimum effective dose, optimal dosage ranges, and maximum safe dose of Tangerine Green Fruit Rind Extract are not well defined. There are no specific timing considerations or form-specific recommendations available. Absorption factors and required cofactors are also unknown. Without further research, it is difficult to provide specific dosing guidelines. It is important to consult with a healthcare professional before using this supplement, especially if you have underlying health conditions or are taking other medications. More research is needed to establish safe and effective dosage recommendations.
FAQs
How do I choose a high-quality Tangerine Green Fruit Rind Extract supplement?
Look for supplements from reputable brands that provide third-party testing for purity and potency. Check the label for the concentration of PMFs and other bioactive compounds. Consult with a healthcare professional for recommendations.
Is Tangerine Green Fruit Rind Extract safe during pregnancy or breastfeeding?
The safety of Tangerine Green Fruit Rind Extract during pregnancy or breastfeeding is unclear due to a lack of data. It is best to avoid using this supplement during these times or consult with a healthcare provider before use.
What are the expected results from taking Tangerine Green Fruit Rind Extract?
The extract is primarily used for its potential antioxidant benefits, but the clinical significance of these effects is uncertain due to limited human studies. Individual results may vary, and it is not a substitute for medical treatment.
Are the health benefits of Tangerine Green Fruit Rind Extract well-established?
No, the health benefits are not yet well-established. While preliminary research is promising, more rigorous human trials are needed to confirm its efficacy and safety for various health conditions.
Research Sources
- https://academic.oup.com/nutritionreviews/article/82/9/1292/7272715 – This review discusses the potential benefits of citrus fruits for weight management and metabolic health. While not specific to tangerine extract, it provides context on the broader health effects of citrus consumption, highlighting the need for more targeted research on specific citrus varieties and extracts.
- https://www.frontiersin.org/journals/sustainable-food-systems/articles/10.3389/fsufs.2022.1003144/full – This study focuses on the sustainable food systems and the role of citrus fruits. It highlights the presence of bioactive compounds in tangerines, such as PMFs, which have antioxidant properties. The research underscores the importance of further investigation into the specific health benefits of tangerine extracts.
- https://www.science.gov/topicpages/t/tangerine+citrus+reticulata – This resource provides access to scientific information related to tangerines (*Citrus reticulata*). It serves as a gateway to research findings and publications, offering insights into the various aspects of tangerine cultivation, composition, and potential applications.
- https://ouci.dntb.gov.ua/en/works/4VY5EBq7/ – This resource provides information on the biochemical composition and potential uses of tangerines. It may contain data on the levels of bioactive compounds and their potential health effects, contributing to a better understanding of the nutritional value of tangerines.
- https://pureadmin.qub.ac.uk/ws/portalfiles/portal/156095550/Citrus_fruits_intake_and_oral_cancer_risk_A_systematic_review_and_meta_analysis.pdf – This systematic review and meta-analysis examines the relationship between citrus fruit intake and oral cancer risk. While not specific to tangerine extract, it provides evidence on the potential health benefits of citrus fruits, including their role in cancer prevention, which may be relevant to understanding the broader health effects of tangerine consumption.
