Superpure Cissus Quadrangularis Extract
Also known as: Cissus quadrangularis, Veld grape, Devil's backbone, Asthisamharaka
Overview
Cissus quadrangularis is a plant native to Africa and Asia, traditionally used in Ayurvedic medicine. It is available as a herbal supplement, often promoted for bone health, weight management, and hemorrhoid treatment. The plant is rich in vitamins, minerals, and antioxidants. While some studies suggest potential benefits in these areas, the overall quality of evidence is variable, with limited systematic reviews and some studies lacking robust methodology. It is available in various forms, including capsules and extracts. Further research is needed to fully establish its efficacy and safety.
Benefits
Some studies suggest potential benefits in bone health and weight management, although the evidence is not consistently strong. It may be beneficial for individuals with bone fractures or those seeking weight loss, but more research is needed to confirm these effects. Limited data suggests potential anti-inflammatory and antioxidant effects. A systematic review and meta-analysis on hemorrhoid treatment showed no statistical difference from conventional treatments. Overall, the clinical significance and effect sizes are not well-established, and the time course of benefits is not well-documented.
How it works
Cissus quadrangularis may influence bone and fat metabolism, potentially interacting with the skeletal and metabolic systems. However, the primary biological pathways and known molecular targets are not well-defined. Limited data is available regarding its absorption and bioavailability. Further research is needed to elucidate the precise mechanisms of action.
Side effects
Cissus quadrangularis is generally considered safe, but comprehensive safety data are lacking. Common side effects are not well-documented, but potential gastrointestinal issues have been reported. Rare side effects are not well-documented. Potential interactions with blood thinners or diabetes medications exist, although these have not been extensively studied. It is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Caution is advised in individuals with diabetes or bleeding disorders.
Dosage
The minimum effective dose of Cissus quadrangularis is not established. Typical dosage ranges are between 500-1000 mg per day, although optimal dosing remains unclear. The maximum safe dose is also not well-defined. There are no specific timing recommendations. Capsules or extracts are common forms. Limited data is available regarding absorption factors. Required cofactors are not established. Consult with a healthcare provider before use to determine appropriate dosage.
FAQs
How should I use Cissus quadrangularis?
Ensure high-quality sourcing and consult a healthcare provider before use. There are no specific timing recommendations. It is available in capsules or extracts.
Is Cissus quadrangularis safe?
While generally considered safe, comprehensive safety data are lacking. Consult with a healthcare provider before use, especially if you have existing health conditions or are taking medications.
What results can I expect from taking Cissus quadrangularis?
Expected results are variable, depending on the condition being treated. Overestimation of its efficacy without robust clinical evidence is a common misconception.
Are there any contraindications?
Cissus quadrangularis is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Caution is advised in individuals with diabetes or bleeding disorders.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/28165166/ – This review suggests potential efficacy of Cissus quadrangularis in various conditions but highlights a need for more systematic reviews. It points out the lack of comprehensive safety and efficacy data, indicating that more robust clinical trials are necessary to validate its benefits.
- https://www.ncbi.nlm.nih.gov/books/NBK77950/ – This source notes Cissus quadrangularis as effective in managing certain conditions, though specific details are not provided. It is part of a broader review of herbal medicines, so the focus on Cissus quadrangularis is not exclusive, limiting the depth of information.
- https://onlinelibrary.wiley.com/doi/10.1002/ptr.5783 – This review examines the efficacy and safety of Cissus quadrangularis, suggesting its potential in managing various conditions. However, it emphasizes the need for more systematic reviews to establish its benefits and safety profile definitively.
- https://www.microbiochemjournal.com/fulltext/ijcmbt/ijcmbt-aid1016.php – This article discusses the potential benefits of Cissus quadrangularis, but specific details are not provided. It highlights the need for more systematic reviews to establish its benefits and safety profile definitively.
- https://he01.tci-thaijo.org/index.php/IJPS/article/view/18421 – This systematic review and meta-analysis on hemorrhoid treatment, conducted in Thailand, found no statistical difference from conventional treatments. The study's limitations include a limited geographical scope and evidence base, with a moderate quality assessment due to the limited number of studies.