Standardized Herbal Extract
Also known as: Standardized Herbal Extract, Herbal Supplements, Phytoextracts, Plant Extracts, Standardized Herbal Extracts
Overview
Standardized herbal extracts are concentrated preparations derived from herbal plants, formulated to contain specified quantities of active phytochemicals. These extracts are utilized for various health issues, ranging from mild to moderate depression, immune enhancement, and cognitive support. Common examples include St. John's Wort (*Hypericum perforatum*), known for its antidepressant properties; Ginkgo biloba, often researched for cognitive function; and Astragalus membranaceus, traditionally used for immune enhancement. Although these extracts are generally well-tolerated, the efficacy varies greatly with different herbs and conditions. Current research is still evolving, with a need for more high-quality trials to validate claims of their health benefits.
Benefits
1. **St. John's Wort (*Hypericum perforatum*)**: Effective for treating mild to moderate depression; some systematic reviews suggest efficacy on par or greater than SSRIs. 2. **Astragalus membranaceus**: May enhance immune function; moderate evidence suggests benefits for physical performance in athletes. 3. **Ginkgo biloba**: Some studies indicate cognitive benefits, although research results have been inconsistent. The strength of evidence varies, with more pronounced benefits seen in specific populations. For instance, individuals with psychosomatic disorders tend to experience greater therapeutic effects. Results can also differ based on dosage and duration of treatment.
How it works
Standardized herbal extracts interact with various biological systems based on their active components. For example, St. John's Wort influences neurotransmitter systems that regulate mood, potentially increasing serotonin and dopamine levels. These extracts can also modulate immune responses and cardiovascular functions. However, specific molecular targets are often not clearly defined, making it challenging to pinpoint precise mechanisms. Variations in absorption and bioavailability are impacted by the preparation methods and consumption context.
Side effects
Standardized herbal extracts are generally regarded as safe but may present several side effects. Common adverse effects (>5%) can include gastrointestinal disturbances, while less frequent issues (1-5%) cover allergic reactions and interactions with other medications. Although serious risks are rare (<1%), they can occur, particularly when herbs interact negatively with prescribed drugs, especially those processed in the liver. Contraindications may exist for pregnant or breastfeeding individuals and those on specific medications. Special caution is recommended for older populations or individuals with multiple health conditions.
Dosage
The dosing of standardized herbal extracts varies widely based on the specific herb used. For instance, St. John's Wort commonly ranges between 300-1,200 mg daily. Optimal dosages for most extracts are not well established, and maximum safe doses tend to be ill-defined. Consistent timing of doses may enhance efficacy and reduce side effects. Forms of extracts include capsules, tablets, or teas, with bioavailability varying across different preparation methods. Absorption can be influenced by food intake; therefore, understanding the appropriate form and incorporating potential synergistic cofactors may optimize effects.
FAQs
Are standardized herbal extracts safe?
Generally, they are considered safe, but individual responses vary. Consult a healthcare provider for specific advice.
How effective are standardized herbal extracts?
The efficacy can vary widely based on the herb and the condition; some extracts are supported by strong evidence.
What should I know about drug interactions?
Many herbal extracts can interact with prescription medications, especially those metabolized by the liver; caution is advised.
What is the recommended dosage?
Dosages vary by herb; for example, St. John's Wort is often used at 300-1,200 mg daily.
Research Sources
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1234701/full – This systematic review assessed the efficacy of St. John's Wort for treating depression, finding comparable effectiveness to SSRIs. Study quality varied, indicating a need for more rigorous research.
- https://pubmed.ncbi.nlm.nih.gov/38219250/ – A meta-analysis of carotenoid supplementation showed significant reductions in blood pressure among nonhealthy individuals, highlighting the benefits of botanical supplements in cardiovascular health.
- https://www.mdpi.com/2673-8392/4/1/14 – This systematic review indicated that Astragalus membranaceus may improve physical performance and immune function, although further studies are warranted for stronger conclusions.
Supplements Containing Standardized Herbal Extract
Super Greens Power
MET-Rx
GreenRich Enriching Greens
Natural Factors
GreenRich Enriching Greens
Natural Factors
GreenRich Enriching Greens
Natural Factors
GreenRich Enriching Greens
Natural Factors
GreenRich Enriching Greens Natural Blueberry Flavor
Natural Factors
GreenRich Enriching Greens Natural Blueberry Flavor
Natural Factors
Advanced Multi Raw Superfood
Greens+
Advanced Multi Wild Berry Superfood
Greens+
Advanced Multi Vanilla Chai Superfood
Greens+
Original Superfood Veggie Capsules
Greens+
+PlusShake Raw Chocolate
Greens+
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