Spisar
Also known as: Spisar, spinach extract, 20E, 20-hydroxyecdysone
Overview
Spisar is a proprietary extract sourced from spinach leaves (Spinacia oleracea), standardized to 20-hydroxyecdysone (20E), a naturally occurring ecdysteroid recognized for its anabolic properties. Extracted through eco-friendly processes using purified water, Spisar is primarily utilized to enhance muscle strength and fitness, notably in older adults. Current research on Spisar is limited, primarily focusing on its potential benefits within a singular clinical study. This standardized extract exhibits key characteristics attributed to phytoecdysteroids, which are bioactive compounds derived from plants. There is observable interest in the supplementation of Spisar for promoting muscle health, yet comprehensive clinical verification is still required. Thus, while initial findings are promising, the overall research maturity level remains low, with much of the evidence being drawn from preliminary investigations.
Benefits
Spisar supplementation has been shown to significantly improve muscle strength among adults over 50 years old when combined with a regular resistance training program. One study demonstrated that participants experienced enhanced muscle performance compared to those receiving a placebo, highlighting its potential as an ergogenic aid within this demographic. This benefit is particularly influential on populations experiencing age-related muscle loss. However, the evidence remains predominantly based on a single study with a small sample size. More extensive research is warranted to confirm these advantages and understand the precise effect sizes, as well as the clinical relevance of these findings over time.
How it works
Spisar, through its active component 20-hydroxyecdysone, is believed to influence anabolic pathways associated with muscle growth, possibly enhancing muscle protein synthesis and minimizing muscle damage. Phytoecdysteroids interact with the body's endocrine system, which could facilitate muscle repair and growth post-exercise. However, the specific molecular mechanisms and bioavailability of Spisar remain under-researched, indicating a need for further biochemical studies to clarify its full potential and interaction with muscle physiology.
Side effects
The safety profile of Spisar is largely inferred from its natural origin, with limited clinical data available on adverse effects. Known side effects are not well-documented, with no common side effects reported in current studies. Institutions that have conducted clinical evaluations indicate both no rare and no common side effects. Additionally, no drug interactions or contraindications have been noted. Special population considerations have not raised significant concerns; however, pregnant women, children, and other at-risk groups should approach supplementation with caution until more comprehensive data on long-term impacts is available.
Dosage
The typical dosing regimen established in the existing study involves administering four capsules of 500 mg daily, totaling 2000 mg per day. However, no minimum effective dose, maximum safe dose, or specific timing recommendations have been firmly established based on available data. The capsules represent the standard form of delivery for this supplement. More extensive research is needed to determine optimal dosing strategies and safety thresholds.
FAQs
How long does it take to see benefits from Spisar?
Benefits from Spisar supplementation have been observed over a 12-week period.
Is Spisar safe to use?
It is generally considered safe; however, more extensive data is necessary to confirm this.
When should I take Spisar?
No specific timing is recommended for taking Spisar.
What results can I expect from using Spisar?
Expected results include improved muscle strength, especially in older adults.
Can I replace exercise with Spisar?
No, Spisar is not a substitute for exercise; its benefits are enhanced when used alongside resistance training.
Research Sources
- https://www.nutritionaloutlook.com/view/spinach-extract-supports-muscle-strength-in-adults-over-50-says-recent-study – A recent study indicated that spinach extract (Spisar) combined with resistance training significantly boosts muscle strength in adults over 50, suggesting its potential as a dietary supplement for this population.
- https://www.e-epih.org/journal/view.php?number=1496 – This journal article provides a comprehensive overview of phytoecdysteroids and their effects on muscle strength, discussing their biological activity and possible applications in dietary supplements.
