ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Sodium Copper Chlorophyllin Compex

Also known as: Copper chlorophyllin complex, Sodium salt, Sodium Copper Chlorophyllin

Overview

Sodium copper chlorophyllin (SCC) is a semi-synthetic derivative of chlorophyll, a green pigment primarily found in plants. This water-soluble compound is utilized as both a dietary supplement and food colorant. It possesses potential antioxidant and anti-inflammatory properties, with primary applications in enhancing skin health by addressing conditions such as acne and photodamage. SCC has shown notable stability during digestion, suggesting its effective absorption in the human intestine. Despite its promising attributes, research on SCC is still limited, largely comprising small-scale pilot studies with no extensive randomized controlled trials or systematic reviews, highlighting the need for more robust clinical investigations to substantiate its efficacy and safety.

Benefits

Sodium copper chlorophyllin has demonstrated effectiveness in improving skin conditions, particularly mild to moderate acne and photodamage. Pilot studies indicate significant improvements in skin appearance, including reductions in visible large pores and solar lentigenes over periods of 3 to 8 weeks. While antioxidant and anti-inflammatory effects have been suggested, the evidence is not robustly quantified in human studies. SCC is particularly beneficial for individuals with specific skin concerns. Though the exact effect sizes are not thoroughly documented due to small sample sizes, the consistency of positive outcomes across studies points to its clinical significance in dermatological applications.

How it works

The mechanism of action of sodium copper chlorophyllin involves its antioxidant and anti-inflammatory properties, likely contributing to tissue repair and skin health. While specific biological pathways are not fully characterized, SCC’s stability during digestion supports its potential absorption into the body, where it may exert beneficial effects on skin tissues. Further research is needed to elucidate its precise interaction with biological systems and determine any molecular targets involved.

Side effects

Sodium copper chlorophyllin is generally regarded as safe with minimal reported side effects in the studies conducted so far. Specific common or uncommon side effects are not well documented, reflecting a need for more comprehensive safety evaluations. There are no significant drug interactions reported, nor are there any notable contraindications for its use in specific populations such as pregnant women or children. However, due to the limited data on its safety profile, caution is recommended for prolonged use or in larger populations until more definitive evidence becomes available.

Dosage

While the minimum effective dose for oral use has not been established, topical formulations of sodium copper chlorophyllin have been utilized effectively at concentrations of 0.1% for addressing acne and 0.066% for photodamage. Optimal dosage ranges and maximum safe doses remain unclear due to insufficient research. Typically, topical applications are recommended for use in the morning and evening. The use of liposomal dispersions enhances its efficacy for skin application, and stability during digestion suggests some potential for systemic absorption if ingested, although full absorption characteristics are not yet characterized.

FAQs

Is sodium copper chlorophyllin safe for long-term use?

Sodium copper chlorophyllin is generally well-tolerated, but extensive long-term safety data is lacking. Consult a healthcare professional for long-term use considerations.

How often should I apply it for skin improvement?

Topical application is recommended twice a day, typically in the morning and evening, for best results in improving skin conditions.

What skin conditions can it help with?

Sodium copper chlorophyllin has been shown to improve acne and photodamage symptoms; however, results may vary among individuals.

Are there any known side effects?

Current research indicates few side effects, but comprehensive safety data is limited; monitoring for unusual reactions is advisable.

Is sodium copper chlorophyllin effective for internal health?

Studies predominantly focus on skin health; its systemic effects are not well understanding, thus requiring further investigation.

Research Sources

  • https://jddonline.com/articles/pilot-study-of-topical-copper-chlorophyllin-complex-in-subjects-with-facial-acne-and-large-pores-S1545961615P0589X/ – This pilot study involving 10 subjects with mild to moderate acne demonstrated the effectiveness of topical sodium copper chlorophyllin in improving acne symptoms after 3 weeks of use. However, limitations included the small sample size and lack of control groups.
  • https://pubmed.ncbi.nlm.nih.gov/11902975/ – An in vitro study examining the stability of sodium copper chlorophyllin during digestion showed promising absorption potential but lacks human application data. This study highlights the compound's structural integrity in digestive conditions.
  • https://jddonline.com/articles/assessment-of-the-safety-and-efficacy-of-topical-copper-chlorophyllin-in-women-with-photodamaged-fac-S1545961615P0401X/ – Conducted over 8 weeks with 10 female subjects, this pilot study noted improvements in photodamage symptoms correlating with the use of topical sodium copper chlorophyllin. The quality was limited due to small sample size and duration.
  • https://pubmed.ncbi.nlm.nih.gov/25844615/ – This meta-analysis delves into the physiological impacts of chlorophyll derivatives, suggesting potential health benefits and emphasizing the need for more specific investigations into individual compounds like sodium copper chlorophyllin.
  • https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/chlorophyll-metallo-chlorophyll-derivatives – The Linus Pauling Institute provides a detailed overview of chlorophyll and its derivatives, discussing their dietary sources and potential health benefits, including the implications of sodium copper chlorophyllin.