Silbinol
Also known as: Silbinol, Pterocarpus marsupium extract
Overview
Silbinol is an extract derived from the heartwood of *Pterocarpus marsupium*, a tree native to India, recognized for its potential antioxidant properties. The extract is thought to contain various bioactive compounds, including flavonoids, which may contribute to its health benefits. While Silbinol is used for its antioxidant and anti-inflammatory effects, research supporting its efficacy is limited compared to other herbal supplements. Available studies primarily focus on its chemical properties rather than comprehensive clinical effects, with most evidence supporting its role as an antioxidant and its possible influence on metabolic parameters. However, the overall quality of research is low, given the lack of systematic reviews and large-scale studies, which creates uncertainty in baseline effectiveness and application.
Benefits
Silbinol is believed to provide antioxidant and anti-inflammatory benefits; however, evidence for these claims remains limited. Some preliminary studies suggest it may help improve blood glucose levels and lipid profiles, particularly in metabolic conditions. No specific populations or well-defined effect sizes have been documented, and thus far, clinical significance is uncertain. The time course for any potential benefits has not been established, underscoring the necessity for further research to clarify its efficacy. Overall, while some potential benefits exist as per early findings, they are not robustly supported with high-quality data.
How it works
Silbinol likely operates through cellular antioxidant pathways, which can help mitigate oxidative stress in the body. These properties may interact with metabolic and cardiovascular systems, possibly enhancing lipid profiles and glucose metabolism. However, specific molecular targets and detailed biological pathways remain poorly characterized, and data on absorption and bioavailability is limited. This lack of understanding complicates the comprehensive evaluation of its mechanisms of action.
Side effects
Silbinol is generally considered safe for short-term use based on available studies, with no common side effects reported. However, the absence of extensive long-term safety data raises concerns regarding potential chronic use. Uncommon and rare side effects cannot be identified due to insufficient research. Moreover, drug interactions have not been well studied, and no specific contraindications have been documented. Special considerations for pregnant women, children, or individuals with severe health conditions are also lacking. Users are advised to proceed with caution given the limited safety data.
Dosage
No established effective dosage for Silbinol exists, with optimal dosages remaining undefined in scientific literature. Commonly available in extract forms, there are currently no specific timing recommendations or maximum safe dosage limits identified. The lack of comprehensive studies leaves absorption factors and cofactor requirements undocumented. Potential users should employ caution regarding dosages and consult healthcare professionals for individualized advice, especially given the uncertainties surrounding effective and safe use.
FAQs
What should I know before using Silbinol?
Consult your healthcare provider before usage, as research on safety and efficacy is limited.
Is Silbinol safe for long-term use?
It is generally safe for short-term use, but long-term safety data is lacking.
Are there specific times to take Silbinol?
No specific timing or administration guidelines are currently established.
What results can I expect from taking Silbinol?
Limited evidence suggests potential antioxidant benefits, but specific health outcomes are not well-defined.
Is Silbinol better than other supplements like curcumin?
Silbinol is less studied than curcumin, making it difficult to compare efficacy directly.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/37671486/ – This study provides some insights into metabolic effects of *Pterocarpus marsupium*, which may relate to Silbinol; however, direct evidence on Silbinol itself is lacking.
- https://sami-sabinsagroup.com/sami-sabinsa-publications/research-papers – This source details various publications related to herbal extracts, including those discussing broader benefits of *Pterocarpus marsupium*, yet specific studies on Silbinol are absent.
- https://silbinol.com/newsroom/press-release/year-2019/published-analysis-of-curcumin-research-provides-comprehensive-overview/ – This analysis discusses curcumin research, highlighting gaps in comparable studies for Silbinol, indicating a need for further investigation in safety and clinical efficacy.
- https://silbinol.com/benefits/clinical-evidence/ – This page outlines the general benefits associated with Silbinol, though it acknowledges the limited scope of research available to substantiate those claims.
- https://www.researchgate.net/figure/Efficacy-analysis-lipids-and-blood-pressure-Interpretation-Expected-changes-in-an_fig1_264201950 – This research analysis examines lipid and blood pressure changes, which could potentially relate to Silbinol; however, again, specific studies on Silbinol are lacking.
Supplements Containing Silbinol

Glycemic Vibrance H
Vibrant Health

Glycemic Vibrance H Natural Orange-Mango Flavor
Vibrant Health

The Worlds Finest Resveratrol 250 mg
Reserveage Organics

Nrf2 Boost
Pure TheraPro Rx

Glucose Control Formula
Beyond Health

Pterostilbene
Sunergetic

Blood Sugar Support
Health Products Distributors

Glucose Essentials
Whitaker Nutrition

Glucose Essentials
Whitaker Nutrition

Morphovita
MN Morphogen Nutrition