Get Your Personalized Supplement StackSupplement Stack Quiz

Sexual Performance Blend

Also known as: Ginseng, Tribulus, L-arginine, Carnitine derivatives, Sexual Performance Blend

Overview

Sexual Performance Blend is a proprietary mix of nutraceuticals and herbal extracts designed to enhance male sexual function. Common ingredients include Panax ginseng, Tribulus terrestris, L-arginine, propionyl L-carnitine (PLC), and acetyl L-carnitine (ALC). These blends aim to improve erectile function, libido, and overall sexual performance, particularly in men with erectile dysfunction. The ingredients are derived from plant extracts and amino acids known for their traditional use in sexual enhancement. These blends work by improving nitric oxide (NO) production, enhancing blood flow, reducing oxidative stress, and supporting mitochondrial function. Research on these blends is moderately mature, with several randomized controlled trials (RCTs) and meta-analyses available, although evidence varies by ingredient and combination. Systematic reviews and meta-analyses suggest that some ingredients have statistically significant effects, especially when combined with phosphodiesterase type 5 inhibitors (PDE5i).

Benefits

The primary benefits of Sexual Performance Blend ingredients include improved erectile function, particularly when L-arginine is combined with PDE5 inhibitors. Studies show that a combination of propionyl L-carnitine, acetyl L-carnitine, and Sildenafil is highly effective in improving erectile function. Panax ginseng and Tribulus terrestris have also demonstrated some improvement in male sexual function, though effect sizes vary. Secondary benefits may include antioxidant properties and improved endothelial function. These blends appear to be more effective in men with organic ED, especially when combined with PDE5 inhibitors, and less effective in non-organic ED. Benefits are typically observed within 4-12 weeks of supplementation.

How it works

Sexual Performance Blend ingredients work through several biological pathways. L-arginine enhances nitric oxide synthesis, which is crucial for vasodilation and improved blood flow. The antioxidant activity of some ingredients reduces oxidative stress, further supporting endothelial function. Carnitines improve mitochondrial energy metabolism, enhancing cellular function. Tribulus terrestris may have androgenic effects, contributing to hormonal balance. These mechanisms interact with the cardiovascular, nervous, and endocrine systems to promote sexual function.

Side effects

Sexual Performance Blend ingredients are generally safe when used at recommended doses and are well-tolerated in clinical trials. Common side effects include mild gastrointestinal discomfort and headache. Uncommon side effects may include allergic reactions and mild hypotension. Serious adverse events are rare. Potential drug interactions include additive hypotensive effects with PDE5 inhibitors, so caution is advised with antihypertensive drugs. Contraindications include known hypersensitivity to any of the components. Limited data exists for women and younger men, as studies primarily focus on middle-aged and older men with ED.

Dosage

Dosage recommendations vary by ingredient. For L-arginine, a minimum effective dose is 3-5 g/day. Panax ginseng is typically used at 200-400 mg/day of a standardized extract. Combination therapies, such as PLC and ALC, are used at doses around 1-2 g/day each. L-arginine is generally well-tolerated up to 6 g/day, but higher doses may increase side effects. Daily dosing is recommended for several weeks, with some studies using a duration of 4-12 weeks. Standardized extracts are preferred for consistency. Taking the supplement with meals may help reduce gastrointestinal side effects.

FAQs

Are these blends effective alone or only with PDE5 inhibitors?

Some ingredients like L-arginine and carnitines show better efficacy when combined with PDE5 inhibitors, especially in organic ED.

Are there risks of serious side effects?

Serious adverse effects are rare; mild side effects are possible, such as gastrointestinal discomfort or headache.

How soon can benefits be expected?

Improvements are typically seen within 4-12 weeks of consistent use, depending on the specific ingredients and individual response.

Can these supplements replace prescription ED medications?

They may complement but not replace PDE5 inhibitors in moderate to severe ED. Consult with a healthcare professional for personalized advice.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/37686709/ – This study is a meta-analysis that investigates the efficacy of various nutraceuticals in combination with PDE5 inhibitors for erectile dysfunction. It concludes that propionyl-L-carnitine, acetyl-L-carnitine, and sildenafil showed the highest efficacy in improving erectile function, particularly in men with organic ED.
https://pubmed.ncbi.nlm.nih.gov/39279185/ – This meta-analysis examines the effects of Panax ginseng, Tribulus terrestris, and L-arginine on male sexual function. The study suggests that these ingredients can improve various aspects of sexual function, although the effect sizes may vary depending on the specific ingredient and study population.
https://www.mdpi.com/2072-6643/15/17/3677 – This study provides a comprehensive review of various supplements and their impact on sexual health. It highlights the potential benefits of several ingredients commonly found in sexual performance blends, emphasizing the importance of understanding their mechanisms and clinical evidence.
https://academic.oup.com/jsm/article-abstract/22/Supplement_2/qdaf077.066/8127416 – This abstract discusses the potential role of nutraceuticals in improving erectile dysfunction, particularly when combined with conventional treatments. It suggests that certain combinations can enhance the effectiveness of PDE5 inhibitors and improve overall sexual satisfaction.
http://sif2022-production.s3.amazonaws.com/uploads/attachment/file_it/1788/Borrelli_2018_Drugs.pdf – This systematic review and meta-analysis evaluates the efficacy of herbal supplements, including ginseng, saffron, and Tribulus, in treating erectile dysfunction. The review concludes that these supplements show promise in improving ED symptoms, but notes the heterogeneity in herbal preparations and the potential for bias in some studies.