ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Sambucus Black Elderberry Fruit Juice Extract

Also known as: Black Elderberry, European Elder, *Sambucus nigra*

Overview

Black Elderberry (*Sambucus nigra*) is a deciduous shrub native to Europe and North Africa, widely recognized for its medicinal properties attributed primarily to its berries. These berries are rich sources of anthocyanins and other polyphenolic compounds that contribute to their antioxidant effects. Traditionally, elderberry extracts are utilized for alleviating cold and flu symptoms, and they exhibit a variety of other potential health benefits. The extracts can be found in several forms, including syrups, liquids, capsules, and lozenges. Although there is a growing interest in the health effects of elderberry, the existing body of research is comprised largely of small-scale studies with limited large-scale clinical trials, pointing to a need for more robust evidence to confirm efficacy and safety.

Benefits

Elderberry extracts are primarily known for their ability to reduce the duration and severity of upper respiratory symptoms associated with viral infections, particularly the common cold and influenza. Some studies suggest a significant mean effect size in symptom reduction. While there are indications of potential antioxidant, antibacterial, and anti-inflammatory actions, these effects require further substantiation. The most pronounced benefits seem to be in individuals prone to frequent respiratory infections. Evidence quality is varied, mainly relying on small studies, but a meta-analysis noted significant improvements within days of starting supplementation.

How it works

The antiviral effects of elderberry extracts are believed to result from their ability to inhibit viral replication and prevent the entry of viruses into host cells. These effects are thought to involve the immune system, enhancing the body's antiviral responses. Key active compounds, particularly anthocyanins, interact with biological pathways that promote health. However, the bioavailability of these compounds may be limited due to rapid metabolism.

Side effects

Black elderberry is generally considered safe when processed correctly, but it can cause gastrointestinal upset in some users. Rare allergic reactions have been reported, but these events are infrequent. Caution is advised in individuals on diabetes medications, as elderberry may have antidiabetic effects. Raw or unripe berries contain cyanogenic glycosides, which can be toxic; therefore, consumption of only processed extracts is recommended. Pregnant or breastfeeding women should consult healthcare professionals due to insufficient safety data in these populations. Overall, while side effects are generally mild, comprehensive safety data is limited, necessitating careful use.

Dosage

Recommended dosages of elderberry extracts vary widely, with typical ranges between 500 mg to 1,000 mg per day when treating cold or flu symptoms. The timing of consumption is crucial; it is often suggested to begin supplementation at the onset of symptoms for optimal efficacy. Liquid extracts, capsules, and lozenges are common forms used, and bioavailability may be improved when taken with food. Currently, maximum safe dosage limits remain undefined, highlighting the need for individualized assessment based on formulation and user health status.

FAQs

When should I start taking elderberry supplements?

For optimal effects, begin supplementation at the onset of cold or flu symptoms.

Are elderberry extracts safe?

Yes, processed elderberry extracts are considered safe; however, avoid consuming raw berries.

How should I take elderberry?

Follow the product label for specific dosing and administration recommendations.

What results can I expect from taking elderberry?

Reduction in severity and duration of respiratory symptoms is commonly reported.

Can elderberry replace standard medical treatment?

It should not replace standard medical treatments; consult your healthcare provider for severe symptoms.

Research Sources

  • https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.2729 – This systematic review assessed the antioxidant and antiviral properties of elderberry fruit preparations. It highlighted the need for more rigorous clinical studies to establish efficacy in treating viral infections.
  • https://pubmed.ncbi.nlm.nih.gov/30670267/ – A meta-analysis indicating that elderberry significantly reduces upper respiratory symptoms. The findings support the potential use of elderberry as a therapeutic alternative for viral infections.
  • https://pubmed.ncbi.nlm.nih.gov/19548290/ – This review discusses the antiviral properties of black elderberry, calling attention to the existing gaps in research, particularly in comparative studies with standard antiviral medications.
  • https://pubmed.ncbi.nlm.nih.gov/28198157/ – This article examines the safety and efficacy of elderberry extracts, reinforcing its generally recognized safety status while emphasizing the importance of using processed forms.
  • https://www.mdpi.com/2227-9717/10/11/2288 – This multifunctional analysis examined elderberry's bioactive compounds and their health benefits, advocating for more extensive research and standardized trials to validate therapeutic claims.

Recommended Articles

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal Boosters & COVID-19 Antivirals: Safe Mix?

Herbal supplements may interact with COVID-19 antivirals, requiring careful consideration and further research.

Elderberry for Immunity: Ingredients & Doses

Elderberry for Immunity: Ingredients & Doses

Elderberry contains anthocyanins, flavonoids, and phenolic acids that enhance immunity, with 300-600 mg daily recommended for effectiveness.

Boost Immunity in Cold Season: Key Ingredients

Boost Immunity in Cold Season: Key Ingredients

Vitamin D and zinc are crucial for immune health during the cold season, with proper intake and potential side effects to consider.

Elderberry & Autoimmune Meds: A Safety Guide

Elderberry & Autoimmune Meds: A Safety Guide

Elderberry supplements can boost immune response, posing risks for individuals on autoimmune medications.