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L. Salivarius

Also known as: L. salivarius, Lactobacillus, salivarius, Lactobacillus salivarius

Overview

Lactobacillus salivarius is a species of lactic acid bacteria commonly found in the human oral cavity and gastrointestinal tract. It is also present in various fermented foods such as yogurt and kefir. This probiotic supplement is primarily utilized to enhance gut health, promote oral hygiene, and bolster immune function. By producing lactic acid, L. salivarius helps maintain a healthy pH balance in both the gut and mouth. Research on this probiotic is moderately mature, with several systematic reviews and meta-analyses providing significant insights into its efficacy and safety, especially in managing halitosis. Overall, L. salivarius is recognized for its ability to positively influence the microbial environment in the human body.

Benefits

Lactobacillus salivarius has shown efficacy in reducing symptoms of halitosis. A meta-analysis indicated a significant decrease in organoleptic scores and levels of volatile sulfur compounds (VSCs), with a standardized mean difference (SMD) of -0.58 in short-term studies lasting up to 4 weeks. While the primary focus is on halitosis management, ongoing research suggests potential benefits for gut health and immune support. The overall effect sizes for oral and gastrointestinal health improvements range from moderate to large. Most research has concentrated on adult populations, resulting in limited data for children or individuals with specific health conditions. Long-term benefits have been observed particularly in treating halitosis.

How it works

Lactobacillus salivarius exerts its beneficial effects by colonizing the oral cavity and gastrointestinal tract, where it produces lactic acid, modulating the local microbiota. This metabolic process reduces the production of volatile sulfur compounds, which are major contributors to halitosis. While the specific molecular mechanisms are not fully elucidated, L. salivarius's capability to produce antimicrobial substances and its influence on bacterial populations are considered essential for its efficacy in promoting oral and gut health.

Side effects

Lactobacillus salivarius is generally regarded as safe when used as a probiotic, with mild gastrointestinal symptoms like gas, bloating, and abdominal discomfort occurring in a small percentage of users. More severe side effects are rare, typically arising in individuals with pre-existing health conditions, especially those with compromised immune systems. No significant drug interactions have been reported, though individuals on immunosuppressive therapies should exercise caution. Pregnant or breastfeeding women, as well as those with underlying health issues, should consult a healthcare provider before using L. salivarius to ensure safety. While serious side effects are uncommon, guidance from healthcare professionals is recommended for individuals with specific health needs.

Dosage

Although there is no universally established minimum effective dose for Lactobacillus salivarius, typical dosages range from 1 to 10 billion CFU (colony-forming units) per day, depending on individual health goals. For halitosis management, studies suggest a daily intake of 1 to 5 billion CFU for optimal results. While doses exceeding 10 billion CFU are generally not recommended without medical supervision, effective probiotic supplementation does not rely on absorption but rather on the bacteria's ability to survive transit through the stomach to colonize the intestines. It is advised to take these probiotics with meals to enhance efficacy and survival rates in the gastrointestinal tract. Probiotic formulations may include capsules, tablets, or powders, with selection often depending on personal preference.

FAQs

How long does it take to see benefits?

Benefits in halitosis management can typically be observed within 4 weeks of consistent use.

Are there any interactions with medications?

Generally, no significant interactions have been reported, but caution is advised in individuals taking immunosuppressive medications.

Can it be used by everyone?

Lactobacillus salivarius is generally safe, though individuals with underlying health issues should consult their healthcare provider first.

What are the common side effects?

The most common side effects include mild gastrointestinal symptoms such as bloating and gas.

When should I take it?

L. salivarius can be taken at any time; however, it is often recommended to take it with meals.

Research Sources

https://www.ncbi.nlm.nih.gov/pubmed/29273691 – This meta-analysis evaluates the effectiveness of Lactobacillus salivarius in managing halitosis, showing significant reductions in organoleptic scores and volatile sulfur compounds. The study highlights the success of this probiotic in enhancing oral health.
https://pubmed.ncbi.nlm.nih.gov/31843765/ – This systematic review discusses the potential benefits of various Lactobacillus species, including L. salivarius, in gastrointestinal health and immune support, suggesting moderate to large effects particularly in adult populations.