Rosemary Leaf Extract
Also known as: Rosmarinus officinalis L., rosemary extract, rosemary oil, rosemary herb, Rosemary Leaf Extract
Overview
Rosemary (*Rosmarinus officinalis* L.) is a fragrant perennial herb native to the Mediterranean, valued for both its culinary uses and potential health benefits. It contains bioactive compounds such as carnosic acid, carnosol, and rosmarinic acid, which are known for their antioxidant, anti-inflammatory, and cognitive-enhancing properties. Science supports its efficacy across various applications including dietary supplements and food preservation, highlighting its significant health benefits. The extraction method, particularly supercritical CO₂, enhances the bioavailability and stability of these compounds, ensuring optimal incorporation into supplements. As a result, rosemary is praised not only for its flavor but also for its role in promoting health and wellness across different populations.
Benefits
Rosemary extracts provide noteworthy antioxidant benefits, significantly slowing oxidation in food products (p < 0.001). Research, mainly from animal studies, indicates robust evidence of cognitive enhancement with effect sizes of 1.19 for healthy individuals and 0.57 for those with cognitive impairments. Additionally, its anti-inflammatory and antimicrobial properties bolster its therapeutic capabilities. Individuals suffering from cognitive impairments, such as Alzheimer's disease, may particularly benefit from rosemary's cognitive-enhancing effects, offering a potential complementary option in managing such conditions.
How it works
The mechanisms behind rosemary's benefits involve multiple biological pathways. Its antioxidant activity neutralizes free radicals, while anti-inflammatory effects modulate immune responses. Key compounds, particularly carnosic and rosmarinic acids, engage pathways related to oxidative stress and inflammation, yielding neuroprotective effects. Supercritical CO₂ extraction optimizes the solubility and stability of these active ingredients, enhancing their bioavailability upon ingestion.
Side effects
Rosemary extracts are generally well-tolerated, although some individuals may experience gastrointestinal discomfort or mild allergic reactions, reported in over 5% of study participants. Severe allergic reactions are rare, with incidences below 1%. Caution is advised for individuals taking anticoagulant medications or those on drugs metabolized by the liver due to potential interactions. Pregnant and nursing women should consult healthcare professionals prior to use, given insufficient safety data. Additionally, individuals with epilepsy or on specific medications should seek medical advice to mitigate any risk of interactions.
Dosage
The minimum effective dosage for antioxidant benefits from rosemary extract is approximately 100 mg/kg for oil forms. For cognitive enhancement, studies suggest a recommended daily dosage range of 50 to 500 mg/kg of body weight. Although no definitive upper limit has been established, doses exceeding 1 gram daily are discouraged due to a lack of supporting research. Consistent dosing is critical for maximizing cognitive benefits, with preference for supercritical CO₂ extracts noted for their enhanced bioactive composition. Various factors, including the extraction method and dietary influences, may influence overall bioavailability.
FAQs
Are rosemary extracts safe?
Yes, rosemary extracts are generally safe, but individuals with specific health conditions or those taking certain medications should consult a healthcare provider.
What is the recommended timing for taking rosemary extracts?
Consistent daily dosing is recommended to achieve cognitive benefits.
When can I expect results from using rosemary extracts?
Antioxidant effects are typically immediate, while cognitive benefits may develop over several days to weeks.
Can rosemary cure Alzheimer’s disease?
Rosemary provides cognitive-enhancing benefits but is not a cure for Alzheimer’s disease.