Get Your Personalized Supplement StackSupplement Stack Quiz

Rosa Roxburghii

Also known as: Chestnut Rose, Rosa Roxburghii, *Rosa roxburghii* Tratt, *Rosa roxburghii*

Overview

*Rosa roxburghii* is a plant species indigenous to southwestern China, valued for its fruit in traditional medicine. The fruit is particularly noted for its high content of bioactive compounds, including vitamins, flavonoids, triterpenes, organic acids, and polysaccharides. Its applications span various health benefits, such as antioxidant capacities and potentially antiaging properties. The interest in *Rosa roxburghii* has grown due to its multifaceted therapeutic potential, supported by emerging research that suggests positive effects on oxidative stress, telomerase activation, and microbiota modulation. While comprehensive systematic reviews are lacking, preliminary studies are promising regarding its health-promoting effects.

Benefits

Research indicates that *Rosa roxburghii* supplementation significantly enhances plasma antioxidant capacity and improves the glutathione redox state (p = 0.04, p = 0.03) in healthy adults. Other studies show that extracts can increase telomerase activity and TERT expression in human mesenchymal stem cells, suggesting antiaging benefits. There are also indications of DNA damage protection from oxidative stress and promotion of cell proliferation. Additionally, fermented juice from the fruit has modulated gut microbiota, increased beneficial short-chain fatty acids, and mitigated inflammation in murine models. These effects suggest potential benefits for general health and populations at risk of oxidative stress-related disorders.

How it works

*Rosa roxburghii* enhances antioxidant capacities by interacting with antioxidant enzymes and non-enzymatic substrates, activating telomerase and increasing TERT expression, which correlates with antiaging actions. The fruit also modulates gut microbiota composition, leading to improved digestive health and reduced inflammation, illustrating its multifaceted biological activity.

Side effects

No significant adverse effects have been reported in current studies, indicating a favorable safety profile for *Rosa roxburghii*. Nonetheless, comprehensive safety data are scarce, necessitating cautious use in the absence of long-term studies. There is no evidence of common side effects (greater than 5%), and rare or uncommon events remain undocumented. Potential interactions with other antioxidant supplements may warrant caution. Pregnant or breastfeeding women and individuals with allergies to rose family plants should consult healthcare providers before use.

Dosage

The specific minimum effective dose of *Rosa roxburghii* is not well delineated, although a study indicated beneficial effects from a daily encapsulated supplement over five weeks. No maximum safe dose has been established due to limited research. As per current evidence, consistent daily intake is suggested, with different forms like fruit extracts or fermented juices available depending on health goals. Absorption may be improved in the presence of other bioactive components from food.

FAQs

Is *Rosa roxburghii* safe for long-term use?

Current evidence indicates safety, but long-term effects and interactions with medications require further investigation.

When should I take *Rosa roxburghii*?

Consistent daily intake is recommended, with no specific timing constraints based on current studies.

What benefits can I expect?

Users may experience enhanced antioxidant levels, potential antiaging effects, and improved gut microbiota health over time.

Are there any misconceptions about its use?

Results from *Rosa roxburghii* are gradual and related to long-term health improvements, not immediate drastic changes.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/15782288/ – This study details a randomized, placebo-controlled trial involving 36 healthy subjects that showed a significant increase in plasma antioxidant capacity from *Rosa roxburghii* supplementation over five weeks, although limited by sample size.
https://www.mdpi.com/2304-8158/13/11/1673 – This in vitro study examined the effects of *Rosa roxburghii* fruit extracts on human mesenchymal stem cells, showing increased telomerase activity and protection against DNA damage.
https://pubmed.ncbi.nlm.nih.gov/38735487/ – This research focused on the effects of fermented *Rosa roxburghii* juice in murine models, highlighting its ability to modulate gut microbiota and mitigate lung injury associated with inflammation and oxidative stress.
https://pubmed.ncbi.nlm.nih.gov/32293681/ – This study explores the bioactive compounds in *Rosa roxburghii*, providing insight into its potential health benefits and various applications in dietary supplementation.
https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1447735/full – This article reviews the impact of *Rosa roxburghii* juice on gut health, emphasizing its role in enhancing microbial diversity and reducing inflammation, with implications for overall health.