ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Roman Chamomile Essential Oil

Also known as: Chamaemelum nobile, Anthemis nobilis, Roman chamomile, English chamomile, Garden chamomile

Overview

Roman chamomile essential oil is derived from the flowers of *Chamaemelum nobile* through steam distillation. It's a popular aromatherapy agent and herbal supplement known for its calming and anti-inflammatory properties. Primary uses include reducing anxiety and stress, improving sleep quality, and soothing skin irritations. The oil contains bioactive compounds such as α-pinene, β-pinene, and chamazulene, contributing to its therapeutic effects. While research on the essential oil itself is still growing, studies on chamomile extracts and aromatherapy provide supporting evidence for its benefits. It is generally considered safe for most adults when used as directed, but caution is advised for those with allergies to plants in the Asteraceae family. The oil's distinct aroma and mild sedative properties make it a favored choice for relaxation and wellness practices.

Benefits

Roman chamomile essential oil has demonstrated benefits for anxiety, stress, and sleep quality. A three-arm RCT showed that inhalation of the essential oil significantly reduced depression, anxiety, and stress levels compared to a control group, with effects persisting at a one-month follow-up. Systematic reviews and meta-analyses of chamomile (primarily extracts) indicate significant improvements in sleep quality. Additionally, in vitro and animal studies suggest anti-inflammatory and antioxidant effects, potentially modulating immune cell function. Older adults and individuals with mild anxiety or sleep disturbances may experience the most pronounced benefits. The clinical significance is modest but consistent, with benefits for anxiety and sleep potentially observable within weeks of regular use.

How it works

Roman chamomile essential oil exerts its effects through several biological pathways. It interacts with the central nervous system, producing sedative and anxiolytic effects. Neuroactive ligand-receptor interactions, serotonin (5-HT) release, and cyclic adenosine monophosphate (cAMP) signaling are implicated in its mechanism of action. The oil's anti-inflammatory properties are linked to the modulation of macrophages and CD4+ T cells. Inhalation allows for rapid absorption via olfactory pathways, facilitating quick central nervous system effects. Topical application may provide localized anti-inflammatory and soothing effects on the skin, although absorption through this route is less studied.

Side effects

Roman chamomile essential oil is generally considered safe for most adults when used as directed. Common side effects are rare, but mild skin irritation may occur with topical use. Uncommon side effects include allergic reactions, which are possible in sensitive individuals. Severe allergic reactions, such as anaphylaxis, are extremely rare. No significant drug interactions have been reported in clinical studies, but there is a theoretical risk of interaction with sedatives due to the oil's mild sedative effect. Contraindications include allergy to plants in the Asteraceae family. Due to insufficient data, caution is advised for pregnant or breastfeeding women. It is recommended to perform a patch test before topical use to check for allergic reactions.

Dosage

For inhalation, a common recommendation is 1–3 drops of diluted (1–2%) essential oil in a diffuser or on a tissue, with evening use recommended for sleep and relaxation. For topical application, a 1–2% dilution in a carrier oil is suggested. The minimum effective dose is not well established for the essential oil specifically, but inhalation studies have used three drops of a 1.5% solution nightly. The maximum safe dose has not been definitively established, but undiluted topical application should be avoided. Inhalation is the preferred method for anxiety and sleep, while topical application is suitable for skin soothing. Inhalation offers rapid CNS effects, while topical absorption is limited.

FAQs

How should I use Roman chamomile essential oil?

For anxiety and sleep, use 1-3 drops of diluted (1-2%) oil in a diffuser or on a tissue, especially in the evening. For skin, apply a 1-2% dilution in a carrier oil. Always dilute before topical use.

Is Roman chamomile essential oil safe?

It's generally safe for most adults when used as directed. Perform a patch test before topical use to check for allergic reactions. Avoid if allergic to Asteraceae family plants. Consult a healthcare provider if pregnant or breastfeeding.

How long does it take to see results?

Modest improvements in sleep quality and anxiety may be observed within several weeks of regular use. Effects can vary among individuals. It is not a substitute for medical treatment of severe anxiety or insomnia.

Can I ingest Roman chamomile essential oil?

Ingestion is not recommended unless under the supervision of a qualified healthcare professional. Essential oils are highly concentrated and can cause adverse effects if ingested improperly.

Research Sources

  • https://onlinelibrary.wiley.com/doi/10.1002/ptr.6349 – This systematic review and meta-analysis of 12 RCTs found that chamomile (mostly extract) significantly improved sleep quality and generalized anxiety disorder symptoms. The study highlighted that most studies used chamomile extract rather than the essential oil, and there was limited data on insomnia. The review was considered high-quality with a rigorous methodology.
  • https://journals.sagepub.com/doi/full/10.1177/15347354231164600 – This three-arm parallel RCT (n=183) demonstrated that inhalation of Roman chamomile essential oil (three drops of 1.5% solution) significantly reduced depression, anxiety, and stress compared to a control group. The study focused on an older adult population and had a short-term follow-up. The study had an adequate sample size, proper control, and clear effect sizes.
  • https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.860043/full – This laboratory study (in vitro and ex vivo) showed that chamomile essential oil modulated macrophage and CD4+ T cell function, demonstrating anti-inflammatory and antioxidant activity. The study was mechanistic and used a clear methodology. The relevance to human health needs confirmation through clinical trials.
  • http://apcnopain.com/wp-content/uploads/2016/05/Essential-Oils-for-Pain.pdf – This document discusses the use of essential oils for pain management, including chamomile. It provides general information on the properties and applications of chamomile essential oil for pain relief. Further research is needed to validate these claims.
  • https://pubmed.ncbi.nlm.nih.gov/36948263/ – This study investigates the effects of chamomile essential oil on anxiety and sleep quality. It provides evidence supporting the use of chamomile essential oil as a natural remedy for these conditions. Further research is needed to determine the optimal dosage and long-term effects.

Recommended Articles

Avoiding Stimulants: A Guide for Sensitive Individuals

Avoiding Stimulants: A Guide for Sensitive Individuals

Identify stimulant ingredients to avoid, understand their effects, discover alternatives, and learn label-reading tips for sensitivity.

Top Sleep Aids for Quality Rest Without Grogginess

Top Sleep Aids for Quality Rest Without Grogginess

Melatonin, valerian root, and chamomile improve sleep without causing grogginess.

Herbal Supplements & Prenatal Vitamins: What to Avoid

Herbal Supplements & Prenatal Vitamins: What to Avoid

Certain herbal supplements can negatively interact with prenatal vitamins and are not recommended during pregnancy due to risks.

Top Sleep Supplements of 2025: Efficacy & Safety

Top Sleep Supplements of 2025: Efficacy & Safety

2025's sleep supplements with new ingredients like herbal extracts and amino acids show significant efficacy and safety.