Purples Blend Proprietary Blend
Also known as: Purples Blend, Proprietary Blend, Botanical Blend, Polyphenol Blend, Purples Blend Proprietary Blend
Overview
Purples Blend Proprietary Blend typically refers to a mixture of plant-derived ingredients, often purple-colored fruits and vegetables, known for their antioxidant polyphenols. The exact composition is usually undisclosed due to proprietary blend labeling rules. These blends are marketed for antioxidant support, anti-inflammatory effects, muscle strength, endurance, cognitive function, and overall health enhancement. A key challenge is that proprietary blends do not disclose individual ingredient amounts, only total blend weight, which complicates dose-effect analysis and safety assessments. Research maturity is moderate, with some RCTs on specific blends showing efficacy, but generalizability to all "Purples Blends" is limited due to formulation differences. Quality of evidence is limited by lack of transparency.
Benefits
A randomized controlled trial on a specific proprietary botanical blend (LI12542F6) containing *Sphaeranthus indicus* and *Mangifera indica* extracts demonstrated significant increases in muscle strength and size, and improved endurance in healthy men. The study reported statistically significant improvements (p < 0.05) with clear effect sizes. Polyphenol-rich blends may also support antioxidant defenses and reduce inflammation, though direct evidence from proprietary blends is sparse due to lack of ingredient disclosure. Benefits in muscle performance were observed in healthy adult men in the cited RCT. The LI12542F6 blend showed meaningful improvements in muscle strength and endurance parameters.
How it works
Polyphenols and phytochemicals in the blend may exert antioxidant effects, modulate inflammatory pathways, and influence muscle protein synthesis signaling (e.g., mTOR pathway). These blends can affect muscular, immune, and metabolic systems. Specific components like 7-hydroxyfrullanolide and mangiferin have been studied for anti-inflammatory and antioxidant properties. Polyphenol bioavailability varies widely; standardization of extracts helps ensure consistent phytochemical content.
Side effects
The studied proprietary blend (LI12542F6) was reported to have acceptable safety profiles with no significant adverse events. However, the general safety of proprietary blends depends on individual ingredients and dosages, which are often undisclosed. Common, uncommon, and rare side effects were not reported in the referenced study. Drug interactions are unknown due to the lack of ingredient disclosure. Contraindications are not specified, and caution is advised due to unknown ingredient amounts. Safety in pregnant or lactating women, children, or those with chronic diseases is not established.
Dosage
A minimum effective dose is not established for general "Purples Blend" proprietary blends due to a lack of transparency. The LI12542F6 study used a defined dose standardized for active markers. Optimal dosage ranges are unknown without disclosure of individual ingredient amounts, and a maximum safe dose is not established. Typically, these blends are taken daily, with specific timing depending on the product formulation. They are usually available as capsules or powders. Polyphenol absorption can be influenced by the food matrix and gut microbiota. No required cofactors are specified.
FAQs
Are proprietary blends safe?
Safety depends on the ingredients and doses, which are often undisclosed, making risk assessment difficult. It's crucial to research the brand and look for third-party testing.
Can I know the exact amount of each ingredient?
No, proprietary blends do not disclose individual ingredient amounts by regulation, making it difficult to assess the specific contribution of each component.
Do proprietary blends work?
Some blends like LI12542F6 have demonstrated efficacy in RCTs for muscle strength and endurance, but results cannot be generalized to all blends due to varying formulations.
How long before benefits appear?
Benefits in muscle performance were observed within weeks in the cited study using the LI12542F6 blend. Individual results may vary.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9899043/ – This randomized controlled trial on the LI12542F6 proprietary blend, containing *Sphaeranthus indicus* and *Mangifera indica* extracts, demonstrated significant increases in muscle strength, size, and endurance in healthy men. The study reported statistically significant improvements (p < 0.05) and was standardized for 7-hydroxyfrullanolide and mangiferin. However, the proprietary nature of the blend limits the generalizability of the findings.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10196566/ – This review article discusses the challenges associated with proprietary blends in supplements, highlighting that the lack of disclosure of individual ingredient amounts complicates research and consumer understanding. The article also notes regulatory challenges related to these blends. It emphasizes the need for greater transparency to improve the quality of evidence and consumer safety.
- https://www.nutritionaloutlook.com/view/new-paper-discusses-the-rationale-for-proprietary-blends-in-supplements-and-the-potential-pitfalls-of-how-they-are-regulated – This commentary discusses the rationale behind using proprietary blends in supplements and the potential pitfalls associated with their regulation. It emphasizes transparency and safety concerns related to proprietary blends. While it provides context for the regulatory environment, it offers limited clinical insight.
- https://www.innerbody.com/focus-factor-reviews – This is a review of Focus Factor, a brain supplement. It discusses the ingredients and potential benefits, but it is not a primary research source and should be interpreted as a consumer review.
- https://www.innerbody.com/vital-reds-review – This is a review of Vital Reds, a dietary supplement. It discusses the ingredients and potential benefits, but it is not a primary research source and should be interpreted as a consumer review.
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