Phytocardio Proprietary Blend
Also known as: Plant sterols, Phytostanols, Phytosterol esters, Phytosterols
Overview
Phytosterols are a group of lipid compounds found in the cell membranes of plants, structurally similar to cholesterol. They are primarily sourced from nuts, seeds, vegetable oils, and certain fortified products. Phytosterols are well-studied for their ability to lower LDL cholesterol levels and decrease the risk of cardiovascular diseases. By inhibiting the intestinal absorption of cholesterol, these compounds effectively lower blood cholesterol levels. Numerous systematic reviews and meta-analyses have validated their efficacy in cholesterol management, making them a recommended dietary supplement for cardiovascular health.
Benefits
Phytosterols can lead to a reduction in serum lipoprotein(a) [Lp(a)] levels by 0.025 mg/dl and free fatty acid (FFA) concentrations by 0.138 mg/dl. They are shown to decrease LDL cholesterol levels by 7-10%, particularly benefiting individuals with high cholesterol. Evidence suggests that consistent supplementation can produce noticeable improvements within weeks, enhancing overall cardiovascular health by reducing dietary cholesterol absorption.
How it works
Phytosterols compete with dietary cholesterol for absorption in the small intestine. Their structural similarity to cholesterol allows them to inhibit its uptake, reducing the amount of cholesterol that enters systemic circulation. This action effectively lowers blood cholesterol levels without significant absorption of phytosterols themselves, making them a valuable part of lipid-lowering dietary strategies.
Side effects
Phytosterols are generally safe, though some users may experience gastrointestinal discomfort, including bloating, gas, and diarrhea (frequency >5%). Less common side effects (1-5%) can include changes in bowel habits and mild stomach discomfort. Rare instances (<1%) may lead to severe gastrointestinal issues. While no significant drug interactions are reported, consultation with a healthcare provider is wise for those on cholesterol-lowering medications or for pregnant or breastfeeding women, as limited safety data exist. Individuals with gastrointestinal concerns should seek professional advice before use.
Dosage
The minimum effective dose of phytosterols for reducing cholesterol is approximately 0.8-1 gram per day. Typically, an optimal intake of 1.5 to 3 grams per day is recommended, taken with meals to improve efficacy. Although there is no established maximum safe dose, exceeding 3 grams daily is generally not advised due to reduced benefits and a potential for side effects. To maximize absorption, phytosterols should ideally be consumed alongside dietary fats.
FAQs
How should I take phytosterols?
Take phytosterols with meals to enhance their cholesterol-lowering effectiveness.
Are phytosterols safe?
Generally safe; however, gastrointestinal side effects may occur. Monitor your body's response.
When should I take phytosterols?
It's best to take them with meals, ideally with fatty foods, for optimal absorption.
What results can I expect?
You can expect a reduction in LDL cholesterol levels and improved cardiovascular risk profiles with consistent use.
Do phytosterols affect HDL cholesterol?
No, phytosterols specifically target lowering LDL cholesterol and do not reduce HDL (good) cholesterol levels.
Research Sources
- https://doi.org/10.1038/s41598-018-21692-x – In this meta-analysis, researchers consolidated data from randomized controlled trials showing that phytosterol supplementation effectively reduces LDL cholesterol and improves cholesterol levels in populations with hyperlipidemia.
- https://doi.org/10.1016/j.jfda.2017.06.002 – This systematic review examines the impact of phytosterols on lipid profiles, confirming significant LDL cholesterol reduction and establishing safe dosage ranges for supplementation.
