Get Your Personalized Supplement StackSupplement Stack Quiz

Patrinia

Also known as: Patrinia, Patrinia herb, Patrinia root, Patrinia scabiosifolia, Patrinia villosa

Overview

Patrinia is a genus of flowering plants in the Caprifoliaceae family, with species like *Patrinia villosa* and *Patrinia scabiosifolia* traditionally used in Asian medicine. It is primarily recognized for its purported anti-inflammatory, antimicrobial, and antiviral properties. The plant contains various compounds, including flavonoids, phenolic acids, and terpenoids, which are believed to contribute to its medicinal effects. However, research on Patrinia is limited, with most studies being small-scale or in vitro. This lack of robust clinical trials makes it challenging to validate its traditional uses scientifically. Patrinia is available in various forms, often as an herbal supplement, and is sourced directly from the plant. Due to the limited research, caution is advised when considering Patrinia supplementation.

Benefits

Evidence on the specific health benefits of Patrinia supplementation in humans is limited. Traditional uses suggest potential anti-inflammatory and antimicrobial effects, but these claims require rigorous clinical validation. In vitro studies have indicated potential antioxidant and antiviral activities, but these findings have not been confirmed in human trials. Currently, there is insufficient evidence to support specific population benefits or quantify effect sizes and clinical significance. The time course of any potential benefits is also not well-documented due to the lack of clinical data. Therefore, any perceived benefits are largely based on traditional use rather than scientific evidence.

How it works

The bioactive compounds in Patrinia are believed to interact with inflammatory pathways and microbial targets, but the specific mechanisms of action are not well-characterized in humans. Potential interactions with the immune system and gastrointestinal tract have been suggested, but detailed studies are needed to confirm these interactions. The exact molecular targets of Patrinia's compounds remain unclear in human studies. Additionally, the absorption and bioavailability of these compounds have not been thoroughly investigated in humans, making it difficult to determine how effectively the body can utilize them.

Side effects

Due to the limited data on Patrinia's safety in humans, the overall safety assessment remains uncertain. Long-term safety data is lacking, and there is a potential for allergic reactions or interactions with medications. Common, uncommon, and rare side effects are not well-documented due to the lack of clinical trials. Potential drug interactions have not been thoroughly studied. As a precaution, Patrinia is contraindicated during pregnancy and breastfeeding due to the absence of safety data. Caution is advised for individuals with allergies or sensitivities to plant extracts. It is essential to consult with a healthcare professional before using Patrinia supplements to assess potential risks and interactions.

Dosage

Currently, there is insufficient evidence to establish a minimum effective dose, optimal dosage ranges, or a maximum safe dose for Patrinia supplementation. Timing considerations and form-specific recommendations have not been determined. Absorption factors and required cofactors are also not well-studied. Due to the lack of clinical data, it is not possible to provide specific dosing guidelines. It is crucial to consult with a healthcare professional before considering Patrinia supplementation to determine appropriate and safe usage.

FAQs

What are the practical usage concerns for Patrinia?

Due to the lack of robust clinical evidence, it is advisable to consult healthcare professionals before using Patrinia supplements to ensure safe and appropriate use.

What are the safety considerations for Patrinia?

Safety data is limited, and potential interactions with medications or pre-existing conditions should be carefully considered. Consult with a healthcare provider before use.

What results can I expect from taking Patrinia?

Expected results are not well-documented due to insufficient clinical data. Claims about health benefits are largely based on traditional use rather than scientific evidence.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/37915917/ – This study investigates the protective effects of Patrinia scabiosaefolia extract (PSE) against PM2.5-induced lung inflammation and oxidative stress in mice. The findings suggest that PSE pretreatment can alleviate PM2.5-induced lung injury by reducing inflammation and oxidative stress, indicating its potential as a protective agent against air pollution-related respiratory issues.
https://pubmed.ncbi.nlm.nih.gov/22212388/ – This research explores the anti-inflammatory effects of Patrinia villosa extract (PVE) on mast cell-mediated allergic inflammation. The study demonstrates that PVE inhibits mast cell activation and reduces inflammatory responses, suggesting its potential as a therapeutic agent for allergic diseases.
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.055654 – This article discusses the importance of rigorous clinical trials and meta-analyses in evaluating the efficacy of traditional medicines. It emphasizes the need for high-quality evidence to support claims of health benefits, highlighting the limitations of relying solely on traditional use without scientific validation.
https://www.bmj.com/content/366/bmj.l4673 – This article outlines the challenges in assessing the safety and efficacy of herbal medicines. It underscores the importance of standardized preparations, controlled clinical trials, and comprehensive safety monitoring to ensure the responsible use of herbal supplements.
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.1084455/full – This study investigates the potential of herbal medicines in modulating gut microbiota and improving metabolic health. It highlights the role of specific herbal compounds in promoting beneficial gut bacteria and reducing inflammation, suggesting a novel approach for managing metabolic disorders.