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Organic Stinging Nettle

Also known as: Stinging Nettle, Nettle, Urtica dioica

Overview

Urtica dioica, commonly known as stinging nettle, is a perennial plant native to Europe, North Africa, and parts of Asia. Characterized by its stinging hairs that cause skin irritation upon contact, this plant is rich in bioactive compounds such as flavonoids, terpenes, and carotenoids. Traditionally, stinging nettle has been utilized for a variety of health conditions including type 2 diabetes, benign prostatic hyperplasia (BPH), osteoarthritis, and allergic rhinitis. Research on stinging nettle suggests it possesses anti-inflammatory, diuretic, and potential antidiabetic properties. The existing body of research is moderate, comprising randomized controlled trials (RCTs) and systematic reviews, though further high-quality studies are needed to affirm its efficacy across different applications.

Benefits

Stinging nettle presents several evidence-backed benefits, primarily for glycemic control in type 2 diabetes mellitus (T2DM). A systematic review and meta-analysis demonstrated a significant reduction in fasting blood sugar levels by -18.01 mg/dl (95% CI: -30.04 to -5.97, p < .001) among T2DM patients. Other potential benefits include improvement in BPH symptoms, such as urinary flow rates, although the evidence remains mixed and often includes combination products. Limited studies suggest anti-inflammatory properties beneficial in allergic rhinitis and asthma. The strength of evidence varies; the most robust support is for T2DM management, highlighting clinical significance in patient outcomes.

How it works

Stinging nettle appears to exert its effects through several biological pathways. It may inhibit the production of inflammatory cytokines and prostaglandins, contributing to its anti-inflammatory properties. Furthermore, it demonstrates potential antidiabetic effects by possibly enhancing insulin sensitivity or reducing glucose absorption. The plant's extracts can block histamine release and inhibit mast cell degranulation, affecting the endocrine system and blood sugar regulation. Additionally, it acts as a diuretic, impacting urinary system function, with bioavailability influenced by extraction methods and supplementation form.

Side effects

Stinging nettle is generally recognized as safe when taken orally for up to a year; however, it can lead to gastrointestinal effects such as diarrhea, constipation, and upset stomach in over 5% of users. Skin irritation may occur upon contact with the plant but is less relevant for oral supplementation. Allergy reactions are rare but possible (<1%). Interactions with drugs such as antidiabetic agents may necessitate monitoring of blood sugar levels, warfarin's effectiveness can be reduced due to high vitamin K content, and lithium levels may increase due to decreased excretion. It is contraindicated during pregnancy as it may induce uterine contractions, and breastfeeding is also not recommended due to insufficient research on safety.

Dosage

The minimum effective dosage of stinging nettle is still not firmly established, but studies often utilize dosages from several hundred milligrams to 1,000 mg per day for glycemic control. General recommendations suggest taking the extract with meals to minimize gastrointestinal issues. The maximum safe dosage has yet to be defined; however, prolonged use beyond one year lacks extensive study data. Variability in absorption depends on the extraction method, with lipophilic extracts potentially offering greater efficacy than aqueous or alcohol-based ones. A balanced diet and adequate hydration are recommended to support overall health.

FAQs

Is stinging nettle safe?

Stinging nettle is usually safe when taken orally, but it may interact with certain medications and is not recommended for use during pregnancy and breastfeeding.

When should I take stinging nettle?

It is advisable to take stinging nettle with meals to reduce potential gastrointestinal discomfort.

Can stinging nettle cure diabetes?

Stinging nettle is not a cure for diabetes but may serve as a beneficial adjunct to standard treatment protocols.

Research Sources

  • https://pubmed.ncbi.nlm.nih.gov/31802554/ – A systematic review and meta-analysis involving 401 subjects with type 2 diabetes showed a significant reduction in fasting blood sugar values associated with stinging nettle supplementation. However, heterogeneity among studies and varying methodological quality were noted.
  • https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010538/references – This review assesses the effects of stinging nettle on patients with BPH, demonstrating moderate evidence of symptom improvement, although some studies incorporated combination products which limit individual efficacy assessments.
  • https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=1216&context=jpcrr – Research on the use of stinging nettle for osteoarthritis reported inconclusive results on its superiority to placebo, marking the need for more rigorous studies with larger sample sizes.
  • https://www.webmd.com/vitamins/ai/ingredientmono-664/stinging-nettle – WebMD outlines various uses of stinging nettle including its applications for diabetes and BPH, noting the importance of evidence quality and safety considerations regarding usage.
  • https://onlinelibrary.wiley.com/doi/10.1002/ptr.6535 – This study reinforces the indications for stinging nettle in managing conditions like BPH and highlights the necessity for well-controlled trials to affirm its therapeutic benefits.

Supplements Containing Organic Stinging Nettle

Zeotrex by Global Healing Center
78

Zeotrex

Global Healing Center

Score: 78/100
Prostrex by Global Healing Center
65

Prostrex

Global Healing Center

Score: 65/100
Zeotrex by Global Healing Center
75

Zeotrex

Global Healing Center

Score: 75/100
PaleoGreens Mint Flavor by Designs for Health
73

PaleoGreens Mint Flavor

Designs for Health

Score: 73/100
PaleoGreens Unflavored And Unsweetened by Designs for Health
73

PaleoGreens Unflavored And Unsweetened

Designs for Health

Score: 73/100
Nettle Leaf by Gaia Herbs
65

Nettle Leaf

Gaia Herbs

Score: 65/100
PaleoGreens Lemon-Lime Flavor by Designs for Health
73

PaleoGreens Lemon-Lime Flavor

Designs for Health

Score: 73/100

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