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Organic Sambucus Black Elderberry Extract

Also known as: Sambucus nigra, Black Elderberry, Elderberry

Overview

Black Elderberry (*Sambucus nigra*) is a plant native to Europe and North America, renowned for its berries, which are rich in anthocyanins, flavonoids, and phenolic acids. These bioactive compounds contribute to its antiviral and antioxidant properties. It is traditionally used as an herbal supplement to treat and prevent upper respiratory infections, such as the common cold and influenza. Elderberry's efficacy is supported by several randomized controlled trials (RCTs) and meta-analyses, although more extensive research is needed for definitive conclusions. It is available in various forms, including capsules and syrups, and is generally considered safe when consumed in recommended doses. The berries' high anthocyanin content is believed to inhibit viral replication and modulate immune responses, making it a popular alternative to conventional treatments for viral respiratory infections. Raw or unripe berries should be avoided due to potential toxicity.

Benefits

Black Elderberry supplementation has been shown to reduce the duration and severity of upper respiratory symptoms, particularly in viral infections like influenza. A meta-analysis found a large mean effect size in reducing these symptoms. Some studies suggest that elderberry may have immunomodulatory effects, though evidence is mixed regarding its ability to prevent illnesses. It may be particularly beneficial for individuals seeking alternatives to conventional treatments for viral respiratory infections. The effect size is generally large for symptom reduction, but more data are needed to fully quantify this across different populations. Benefits are typically observed within a few days of supplementation.

How it works

Elderberry's antiviral properties are thought to be mediated through its anthocyanin content, which may inhibit viral replication and modulate immune responses. It interacts with the immune system by potentially reducing inflammation and modulating cytokine production. The exact molecular targets are not fully elucidated but likely involve pathways related to viral entry and replication. The bioavailability of elderberry's active compounds is not well-studied, but anthocyanins are generally poorly absorbed. Further research is needed to fully understand the absorption and bioavailability of its active components.

Side effects

Black Elderberry is generally considered safe when consumed in recommended doses. The most common side effect is gastrointestinal upset, though this is rare. Uncommon side effects include allergic reactions. Potential interactions with immunosuppressive drugs exist due to its immunomodulatory effects. Raw or unripe berries should be avoided due to toxicity. Pregnant or breastfeeding women should consult healthcare providers before use. While rare, it's important to monitor for any adverse reactions and discontinue use if they occur. Individuals with autoimmune conditions should exercise caution and consult with a healthcare professional before using elderberry.

Dosage

Typical doses of Black Elderberry range from 500 to 1000 mg daily, often in divided doses. While the minimum effective dose is not well-established, this range is commonly recommended for treating upper respiratory symptoms. The maximum safe dose is not clearly defined, but doses above 1000 mg per day are not commonly recommended. It is best taken at the onset of symptoms. Capsules or syrups are common forms. Bioavailability may be enhanced with food. There are no specifically identified required cofactors. It is important to adhere to recommended dosages to minimize the risk of side effects.

FAQs

How long does it take to see benefits?

Benefits are typically observed within a few days of starting supplementation, particularly when taken at the onset of symptoms.

Is it safe for pregnant women?

Pregnant or breastfeeding women should consult a healthcare provider before using Black Elderberry to ensure safety.

When is the best time to take it?

For best results, take Black Elderberry at the onset of symptoms of upper respiratory infections.

What results can I expect?

You can expect a reduced duration and severity of upper respiratory symptoms, such as cough, congestion, and fever.

Is Black Elderberry a cure for viral infections?

No, it is not a cure but may help alleviate symptoms and shorten the duration of illness.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/30670267/ – A meta-analysis by Hawkins et al. (2018) found that black elderberry supplementation substantially reduced upper respiratory symptoms. The study included 180 participants and reported a large mean effect size, suggesting a significant benefit in alleviating symptoms associated with respiratory infections. However, the authors noted limitations including the relatively small sample size and the need for more large-scale studies to confirm these findings.
https://pubmed.ncbi.nlm.nih.gov/33827515/ – A systematic review suggests that elderberry may reduce the duration of influenza, but the evidence is uncertain. The review also indicated that elderberry does not appear to increase the risk of cytokine storm, which was a concern during the COVID-19 pandemic. This suggests that elderberry may be a safe option for managing influenza symptoms without exacerbating inflammatory responses.
https://www.tandfonline.com/doi/full/10.1080/09540105.2021.1978941 – This study on a high-quality elderberry extract (eldosamb®) demonstrated antiviral and immunomodulatory effects. The research highlights the potential for elderberry to act against viral infections at a molecular level, suggesting it can interfere with viral replication and modulate the immune response. While specific clinical outcomes were not detailed, the findings support the use of elderberry as a potential therapeutic agent for viral infections.
https://magistralbr.caldic.com/storage/product-files/1899087739.pdf – This document provides information on the properties and potential benefits of elderberry extract. It highlights the antioxidant and anti-inflammatory properties of elderberry, which contribute to its ability to support immune function and reduce the severity of respiratory symptoms. The document also emphasizes the importance of using high-quality elderberry extracts to ensure optimal efficacy.
https://www.mdpi.com/1420-3049/29/13/2971 – This study investigates the antiviral activity of elderberry extract against various influenza viruses. The research demonstrates that elderberry extract can effectively inhibit the replication of influenza viruses, suggesting its potential as a natural remedy for influenza infections. The findings support the traditional use of elderberry for treating respiratory illnesses and highlight its potential as a complementary therapy for managing influenza symptoms.