Organic Hops Flower Extract
Also known as: Hops, Common hops, Humulus, Hop flowers, Hops flower extract, Humulus lupulus
Overview
Hops are the flowers of the *Humulus lupulus* plant, primarily recognized for their critical role in brewing beer and valued in traditional herbal medicine and dietary supplements. These flowers are rich in bioactive compounds, including flavonoids, phenolic acids, and bitter acids, making hops extracts appealing for health applications. Research indicates that hops extracts may help modulate appetite, regulate hormonal responses, and possess antioxidant and anti-inflammatory properties. Notably, components such as alpha-acids, beta-acids, and xanthohumol contribute to these effects. Existing studies, including moderate randomized controlled trials, suggest promising outcomes in appetite regulation. However, further rigorous studies, such as systematic reviews, are needed to firmly establish its efficacy and mechanisms of action.
Benefits
Research indicates that hops extract can effectively regulate appetite and energy intake. A notable double-blind study demonstrated a significant reduction of about 900 kJ in energy intake after administering 500 mg of hops extract (P = 0.006 for gastric delivery). This effect appears linked to ghrelin secretion and hormonal modulation, suggesting its potential for weight management, particularly in healthy-weight men. Additionally, animal studies show promise in reducing weight gain on high-fat diets. Antioxidant and anti-inflammatory properties have been observed, albeit mainly in vitro. For menopausal women, the appetite-regulating effects may address symptoms like hot flashes, although evidence in this area is less robust.
How it works
Hops extract influences appetite regulation through its interaction with enteroendocrine cells in the gastrointestinal tract, affecting the secretion of key gut hormones such as ghrelin and cholecystokinin. The activation of bitter taste receptors in the gut is a pivotal mechanism in this action, where the bioactive compounds present in hops contribute significantly to energy intake regulation and appetite modulation. This interaction with the endocrine system highlights the extract's potential role in influencing metabolic functions.
Side effects
Hops extract is generally safe when consumed in moderation. However, gastrointestinal discomfort is the most common side effect, reported by more than 5% of users, manifesting as nausea, bloating, and abdominal pain, particularly when taken via gastric delivery methods. Less common side effects (1-5%) may include anecdotal reports of potential estrogenic effects, particularly menstrual irregularities among women. Although rare side effects (<1%) have not been well-documented, caution is warranted. Those on hormonal medications should be aware of possible interactions, and pregnant or breastfeeding women are advised to consult healthcare professionals due to potential risks associated with hormonal changes.
Dosage
The effective minimum dose of hops extract for appetite regulation is approximately 200 mg, but higher doses around 500 mg have been more commonly studied and shown efficacy. Recommended intake ranges from 200 mg to 500 mg per day, depending on the specific product and its intended effects. Although there is no well-defined maximum safe dose, it is advisable to avoid exceeding 500 mg given the limited research on higher dosages. Timing of administration may also affect effectiveness; utilizing delayed-release formulations can enhance tolerance and bioavailability, especially when comparing gastric versus duodenal delivery methods.
FAQs
Is hops extract safe for everyone?
While generally safe, hops extract may cause gastrointestinal discomfort in some individuals. Pregnant or breastfeeding women should consult a healthcare provider due to potential estrogenic effects.
How should I take hops extract for optimal results?
The timing and administration method can influence effectiveness; delayed-release capsules may offer better results than quick-release forms.
What benefits can I expect from using hops extract?
Users may experience reduced energy intake and hormonal modulation, potentially supporting weight management efforts.
Can hops extract help with weight loss?
Hops extract is not a standalone solution for weight loss but may assist as part of a balanced diet and exercise regimen.
Research Sources
- https://doi.org/10.1016/j.jff.2020.104134 – This study provides evidence on the appetite-suppressing effects of hops extract, highlighting its significant role in reducing energy intake in a controlled context. The double-blind format strengthens the findings, which are crucial for understanding hops' efficacy in weight management strategies.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522381/ – A review discussing the various bioactive components of hops and their potential health benefits, including antioxidant and anti-inflammatory effects, and insights into their mechanism of action within metabolic pathways.
Supplements Containing Organic Hops Flower Extract
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