ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Organic Cordyceps Extract

Also known as: Cordyceps sinensis, Ophiocordyceps sinensis, Chinese caterpillar fungus

Overview

Ophiocordyceps sinensis, commonly known as Cordyceps, is a parasitic fungus native to the Qinghai-Tibetan Plateau. It has been a staple in traditional Chinese medicine for centuries, valued for its potential to enhance vitality, improve kidney function, and support immune health. The fungus contains bioactive compounds such as cordycepin, cordycepic acid, and polysaccharides, which are believed to contribute to its medicinal properties. It is available in various forms, including capsules and powders, derived from cultivated mycelia or, less commonly, wild-harvested fruiting bodies. Research on Cordyceps is ongoing, with studies exploring its effects on renal function, inflammation, and overall well-being. While some findings are promising, more human studies are needed to fully understand its benefits and safety profile. Ensuring product quality from reputable sources is crucial due to the risk of adulteration.

Benefits

Cordyceps sinensis has shown potential benefits in several areas. A meta-analysis indicated that it can improve renal function by reducing blood creatinine levels and enhancing urine osmolality in patients with renal dysfunction. Furthermore, studies suggest anti-inflammatory effects, primarily demonstrated in animal models. Research also indicates that Ophiocordyceps sinensis may improve nutritional and micro-inflammatory status in dialysis patients. While animal and lab studies have shown antitumor and antioxidant effects, human evidence is still lacking to confirm these benefits. The effects may be observed within weeks to months of consistent use, but individual results can vary. More high-quality human trials are needed to solidify these findings.

How it works

Cordyceps exerts its effects through several biological pathways. It is known for its immunomodulatory properties, influencing the activity of immune cells and cytokines. Additionally, it exhibits antioxidant activity, helping to neutralize free radicals and reduce oxidative stress. The fungus may also possess anti-inflammatory properties, although the exact mechanisms are still under investigation. Cordyceps interacts with the immune system, kidneys, and potentially the cardiovascular system. While the specific molecular targets are not fully understood, it is believed to modulate various immune factors. Limited data exists on human bioavailability, but the bioactive compounds are thought to be absorbed orally.

Side effects

Cordyceps is generally considered safe, with few reported side effects. The most commonly reported side effect is mild gastrointestinal upset. Allergic reactions are possible but rare. Due to limited data, pregnant and breastfeeding women should avoid Cordyceps. Caution is advised for individuals with autoimmune diseases or those taking immunosuppressive drugs, as Cordyceps may interact with these medications. Potential interactions with other medications affecting kidney function should also be considered. While rare side effects are not well-documented, it is essential to monitor for any adverse reactions when starting Cordyceps supplementation. Always consult with a healthcare provider before use, especially if you have underlying health conditions or are taking medications.

Dosage

The minimum effective dose of Cordyceps is not well-established, but typical dosages range from 500 mg to 3 grams per day. The optimal dosage varies based on individual health goals and the specific preparation used. While a maximum safe dose is not clearly defined, high doses have been used in animal studies without significant adverse effects. There are no specific timing recommendations for Cordyceps supplementation. Capsules and powders are common forms. Bioavailability may be enhanced with certain delivery systems. No specific cofactors are required for Cordyceps to be effective. It is advisable to start with a lower dose and gradually increase it to assess tolerance and effectiveness.

FAQs

How do I ensure the Cordyceps product I'm using is safe and effective?

Purchase Cordyceps from reputable sources to avoid adulteration. Look for products that have been third-party tested for purity and potency. Check the ingredient list for any added fillers or artificial ingredients.

Are there any specific precautions I should take while using Cordyceps?

Monitor for allergic reactions or interactions with medications, especially immunosuppressants. If you have an autoimmune condition, consult your healthcare provider before using Cordyceps. Pregnant and breastfeeding women should avoid Cordyceps due to lack of safety data.

When is the best time to take Cordyceps?

There is no specific recommended timing for taking Cordyceps. Consistent daily use is typical. Some individuals prefer taking it in the morning for an energy boost, while others take it before exercise to enhance performance.

What kind of results can I expect from taking Cordyceps?

Results may vary based on individual health status and specific health goals. Some people report increased energy, improved immune function, and enhanced athletic performance. However, more human evidence is needed to confirm these benefits.

Is it safe to take Cordyceps long-term?

Cordyceps is generally considered safe for long-term use, but limited data exists on its long-term effects in humans. It is advisable to monitor for any adverse reactions and consult with a healthcare provider if you have any concerns.

Research Sources

  • https://pubmed.ncbi.nlm.nih.gov/39839641/ – This meta-analysis of 1,310 patients with renal dysfunction found that Cordyceps sinensis improved renal function by reducing creatinine levels and enhancing urine osmolality. The study highlights the potential benefits of Cordyceps in managing renal health, although it notes variability in study quality and regional differences in efficacy. This suggests that while promising, further research is needed to standardize the use of Cordyceps for renal conditions.
  • https://www.ncbi.nlm.nih.gov/books/NBK92758/ – This resource provides general information about herbal medicine, including Cordyceps. While it doesn't offer specific study details, it serves as a broad overview of the use of Cordyceps in traditional medicine. It emphasizes the need for more rigorous scientific investigation to validate the traditional uses and potential health benefits of Cordyceps.
  • https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1360997/full – A systematic review and meta-analysis of 2,914 dialysis patients showed that Ophiocordyceps sinensis improved nutritional and micro-inflammatory status. The study indicates a potential role for Cordyceps in supporting the health of dialysis patients, but the authors note that the certainty of evidence for some outcomes is low to very low. This suggests that while the findings are promising, more high-quality research is needed to confirm these benefits.
  • https://www.researchgate.net/publication/234144712_PubMed_ScienceDirect_Scopus_or_Google_Scholar_-_Which_is_the_best_search_engine_for_an_effective_literature_research_in_laser_medicine – This article discusses the effectiveness of different search engines for literature research. While it doesn't provide specific information about Cordyceps, it is relevant for understanding the methodology used to gather research on the supplement. It highlights the importance of using comprehensive search strategies to identify relevant studies.
  • https://www.healthline.com/nutrition/cordyceps-benefits – This article summarizes potential health benefits of Cordyceps, including improved exercise performance and anti-aging properties. It is a general overview and does not provide in-depth scientific analysis. The article serves as an introduction to the topic but should be supplemented with more rigorous scientific sources for detailed information.

Supplements Containing Organic Cordyceps Extract

Cordyceps Mushroom by Gaia Herbs
73

Cordyceps Mushroom

Gaia Herbs

Score: 73/100
Immune+ Daily wellness by youtheory
70

Immune+ Daily wellness

youtheory

Score: 70/100
Immune Assist Complete by Aloha Medicinals
78

Immune Assist Complete

Aloha Medicinals

Score: 78/100
Calming Liquid Drops by BareOrganics
70

Calming Liquid Drops

BareOrganics

Score: 70/100
ULTIMATE Mushroom Complex by FRESHCAP
70

ULTIMATE Mushroom Complex

FRESHCAP

Score: 70/100
MycoMax® Mushroom Extract Complex by Triquetra MycoMax®
73

MycoMax® Mushroom Extract Complex

Triquetra MycoMax®

Score: 73/100
Clean Adaptogenic Cortisol Energy Supplement by CortiSol Cone
70

Clean Adaptogenic Cortisol Energy Supplement

CortiSol Cone

Score: 70/100
Mushroom Chocolates by alice™
48

Mushroom Chocolates

alice™

Score: 48/100
ULTIMATE Mushroom Complex by freshcap
73

ULTIMATE Mushroom Complex

freshcap

Score: 73/100
Beyond Brew Mushroom... by we live conscious®
70

Beyond Brew Mushroom...

we live conscious®

Score: 70/100
Corti Gone ADAPTOGENIC CORTISOL ENERGY SUPPLEMENT by Clean ALL-IN-ONE
60

Corti Gone ADAPTOGENIC CORTISOL ENERGY SUPPLEMENT

Clean ALL-IN-ONE

Score: 60/100
Mushwa™ 10 Mushroom Complex With Ashwagandha by ETTA | VITA
73

Mushwa™ 10 Mushroom Complex With Ashwagandha

ETTA | VITA

Score: 73/100

Recommended Articles

Mushroom Supplement Extraction: Enhancing Potency

Mushroom Supplement Extraction: Enhancing Potency

Extraction is essential to unlock the full potency of certain mushroom supplements like Reishi, Cordyceps, and Lion's Mane.

Top Adaptogens for Stress Relief: A Scientific Guide

Top Adaptogens for Stress Relief: A Scientific Guide

Adaptogens like Ashwagandha, Rhodiola, and Holy Basil are effective for stress relief, supported by clinical evidence.

Top Low-Side-Effect Energy Supplements

Top Low-Side-Effect Energy Supplements

Adaptogens like Rhodiola and Ginseng, and combinations like L-theanine with caffeine, offer steady energy with minimal side effects.