ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Oregano Powder Extract

Also known as: Oregano, Wild Marjoram, Greek Oregano, Origanum vulgare

Overview

Oregano, scientifically known as *Origanum vulgare*, is a perennial herb native to the Mediterranean region, renowned for its culinary and medicinal uses. Rich in bioactive compounds, particularly carvacrol and thymol, oregano has gained attention for its powerful antimicrobial, anti-inflammatory, and antioxidant properties. It acts as a natural preservative and has shown promise in food preservation and supporting gastrointestinal health. Current research validates its effectiveness against various pathogens while highlighting its potential to modulate gut microbiota positively. Despite a moderate maturity level of studies, the herb's multifaceted benefits underline the need for more comprehensive research, especially in human trials.

Benefits

Oregano powder extract is primarily recognized for its antimicrobial properties, significantly inhibiting the growth of various pathogenic bacteria, with particular success against *Streptococcus* species. A notable study demonstrated that a 1% w/v concentration could decrease pathogenic bacteria while enhancing beneficial short-chain fatty acids (SCFAs) in poultry models. Additionally, oregano's anti-inflammatory and antioxidant effects contribute to better gastrointestinal health by reducing inflammation and fostering a balanced gut microbiota. As a natural food preservative, it may provide an alternative to synthetic additives, and its potential use in animal feeds offers an all-natural substitute for antimicrobial growth promoters. Overall, the statistical significance of these findings supports oregano's clinical relevance in various applications.

How it works

The antimicrobial effects of oregano are primarily attributed to its bioactive compounds, carvacrol and thymol, which disrupt bacterial cell membranes, increasing permeability and leading to cell lysis. This action effectively inhibits the growth of pathogenic bacteria. Additionally, oregano has been shown to modulate gut microbiota, promoting beneficial bacterial populations, which enhances SCFA production—crucial for gastrointestinal health. Its anti-inflammatory and antioxidant properties further bolster its protective capabilities against gut inflammation, involving multiple biological pathways that enhance overall health.

Side effects

Oregano is considered safe for consumption, although high doses or prolonged use should be approached with caution. While no common side effects have been reported, some individuals may experience mild allergic reactions or gastrointestinal disturbances. Severe allergic responses are rare but possible, particularly for those allergic to Lamiaceae family members. Limited evidence on drug interactions suggests possible caution when combined with medications that affect gastrointestinal function. Pregnant and breastfeeding women should use oregano with care due to insufficient safety data, and interactions with other supplements or medications should be watched.

Dosage

The effective dose of oregano powder for antimicrobial properties is approximately 1% w/v, although optimal dosages for specific health applications remain under exploration. Caution is advised for doses exceeding 10 g/day due to potential gastrointestinal side effects. Oregano can be consumed as needed for culinary or supplemental use, without strict timing recommendations. Various forms exist, including powdered and essential oil, and effective dosages may vary based on the desired health benefit. Bioactive absorption can differ by form, but no specific cofactors are required for enhancing effects.

FAQs

Is oregano safe to consume?

Oregano is generally safe for most individuals, but those with allergies or on medications should consult a healthcare provider before use.

When is the best time to take oregano supplements?

There are no specific timing requirements; oregano can be used as needed based on individual health goals.

What health benefits can I expect from oregano?

Expect antimicrobial effects and improvements in gastrointestinal health, although individual responses may vary.

Can oregano replace medical treatments?

Oregano should not be viewed as a substitute for medical treatment; its benefits are supplementary to standard healthcare.

Research Sources

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340355/ – This study demonstrates the antimicrobial properties of oregano essential oil and its potential applications in enhancing food safety and preservation. It emphasizes the effectiveness of carvacrol against various foodborne pathogens and discusses implications for human health and food industry applications.
  • https://www.frontiersin.org/articles/10.3389/fcimb.2019.00134/full – Research highlights oregano's prebiotic effects, showing its ability to stimulate beneficial gut bacteria and enhance SCFA production. The study supports the role of oregano in dietary applications for improving gastrointestinal health and managing inflammation.

Supplements Containing Oregano Powder Extract

Double X by Nutrilite
58

Double X

Nutrilite

Score: 58/100
Candinex by HoltraCeuticals
60

Candinex

HoltraCeuticals

Score: 60/100
Double X by Nutrilite
80

Double X

Nutrilite

Score: 80/100