Ocibest Holy Basil Extract
Also known as: Holy Basil, Tulsi, Sacred Basil, Krishna Tulsi, Rama Tulsi, Ocimum tenuiflorum L.
Overview
Holy Basil, scientifically named Ocimum tenuiflorum L., is a significant herb belonging to the Lamiaceae family and holds a prominent place in Ayurvedic medicine due to its remarkable therapeutic properties. Originating from the Indian subcontinent, Holy Basil is celebrated for its adaptogenic qualities, which assist in effectively managing stress, enhancing sleep, and promoting overall wellness. This herb is rich in key phytochemicals such as rosmarinic acid and luteolin, both contributing significantly to its health benefits. Various clinical trials and animal studies endorse its efficacy, particularly in countering stress-related symptoms, while emerging research indicates additional benefits associated with metabolic health and cardiovascular protection. Continued systematic reviews are needed to further consolidate these findings and address gaps in the research literature.
Benefits
Holy Basil has shown a variety of evidence-based benefits, mainly concerning the alleviation of stress in adults. A noteworthy randomized, double-blind, placebo-controlled trial revealed that a daily intake of 1,200 mg resulted in significant reductions in stress symptoms, providing a 39% improvement over a placebo. Additionally, Holy Basil has been linked to improvements in sleep quality, measured by the Athens Insomnia Scale. Further therapeutic effects include anxiolytic and antidepressant properties, with other studies hinting at its potential advantages for metabolic disorders and heart health. The primary demographic benefiting from Holy Basil is adults experiencing high stress levels, with tangible results often observable within 6-8 weeks of regular use.
How it works
The primary mechanism through which Holy Basil exerts its effects is via modulation of the hypothalamic-pituitary-adrenal (HPA) axis. This action results in decreased cortisol secretion and antagonism of corticotropin-releasing factor 1 (CRF1) receptors. Key bioactive compounds like rosmarinic acid and luteolin interact with the nervous system, effectively reducing stress reactions and contributing to lower plasma corticosterone levels. While specific data regarding its absorption and bioavailability is still limited, standardized extracts of Holy Basil are formulated to ensure consistent efficacy.
Side effects
Generally, Holy Basil is considered safe at clinical dosages ranging from 250 mg to 1,200 mg daily. While common side effects are infrequent and typically mild, there may be instances of increased agitation or nausea in select users, though these are not predominantly linked to the herb itself. Notably, certain vulnerable populations, particularly pregnant and breastfeeding women, should approach Holy Basil with caution due to potential reproductive toxicity observed in animal studies. While research on interactions with drugs is scarce, individuals taking medications that affect metabolic enzymes are advised to consult healthcare professionals to address and mitigate any possible risks.
Dosage
The clinical dosage range for Holy Basil typically spans from 250 mg to 1,200 mg of standardized extract per day. To maximize the benefits for stress relief and sleep enhancement, a daily dosage of about 1,200 mg is recommended, ideally divided into two dosages taken with or without food. Although the precise upper limits for safety are not firmly established, doses up to 1,200 mg have not demonstrated adverse effects in clinical settings. Users are encouraged to utilize quality-controlled extracts, such as Holixer TM, to achieve consistent therapeutic effects; however, specific absorption characteristics remain unspecified.
FAQs
Is Holy Basil safe for everyone?
Holy Basil is generally safe; however, pregnant and lactating women should avoid it due to concerns of reproductive toxicity.
How should I take Holy Basil?
The recommended intake is 1,200 mg daily, taken in two doses with or without food.
When can I expect to see results?
Users often see significant reductions in stress and improved sleep quality within 6-8 weeks of consistent use.
Is Holy Basil a cure for stress?
While Holy Basil is effective for stress management, it is not a cure-all and should be part of an overall wellness strategy.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813316/ – This systematic review analyzes various studies on Holy Basil, affirming its adaptogenic effects and potential for managing stress-related symptoms. The methodology includes randomized controlled trials that yield significant findings on its health benefits, representing a comprehensive look into its efficacy based on diverse clinical evidence.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072079/ – A randomized, double-blind, placebo-controlled trial that investigates the impact of Holy Basil on stress relief, documenting a notable 39% greater relief than placebo, along with improvements in sleep quality as per the Athens Insomnia Scale.
- https://www.sciencedirect.com/science/article/pii/S1836736133000888 – This article discusses the biochemical mechanisms underlying the effects of Holy Basil, with a focus on its interaction with the HPA axis and cortisol regulation, backing claims of its adaptogenic properties and holistic health benefits derived from its phytochemical composition.