Nitrosigine Arginine Silicate Inositol
Also known as: Nitrosigine, Arginine Silicate, Inositol-Stabilized Arginine Silicate, ASI, Inositol-stabilized Arginine Silicate
Overview
Inositol-stabilized arginine silicate (ASI) is a synthetic compound that combines the amino acid arginine, silicate, and inositol to enhance nitric oxide production in the body. Primarily employed in dietary supplements, ASI aims to improve athletic performance, muscle recovery, cognitive function, and blood flow. The compound elevates arginine and nitric oxide levels in the bloodstream, leading to vasodilation and enhanced delivery of oxygen and nutrients to tissues. Research supporting ASI is moderately robust, with several double-blind, placebo-controlled studies affirming its efficacy, though further systematic reviews are warranted. ASI is available in capsule and powder forms and is noted for its rapid absorption, with effects typically manifesting within 15 minutes to an hour post-ingestion.
Benefits
ASI offers various evidence-backed benefits: 1. **Muscle Recovery and Blood Flow:** It significantly lowers serum creatine kinase levels (p < 0.05), indicating reduced muscle damage and enhances reactive hyperemia, with improvements observed within 72 hours post-exercise. 2. **Cognitive Function:** Users have reported a 28-35% enhancement in task performance in standardized cognitive assessments (p < 0.05). 3. **E-Sport Enhancement:** Documented improvements in reaction time and cognitive abilities among e-sport athletes have been noted, especially when combined with inositol. These benefits are particularly confirmed through studies focusing on athletes and gamers, indicating a moderate to high level of research quality.
How it works
ASI increases circulating levels of arginine, a precursor to the vasodilator nitric oxide (NO). This elevation enhances blood flow and oxygenation to tissues, improving athletic performance and mitigating muscle damage. Additionally, ASI positively impacts cognitive function by increasing cerebral blood flow and oxygen supply, leading to enhanced mental clarity and faster processing speeds.
Side effects
ASI is generally regarded as safe, with extensive clinical studies reporting no significant adverse effects among participants. Most users have not experienced common side effects; however, caution is advised for those on vasodilators or anticoagulants due to possible interactions. While no specific contraindications exist, individuals with pre-existing cardiovascular conditions should consult a healthcare provider prior to use. Pregnant or breastfeeding women and those managing chronic health conditions should seek medical advice before supplementation, despite the absence of significant safety concerns documented in the literature.
Dosage
The commonly recommended dosage for ASI ranges from 1500 mg to 1600 mg per day, with 1500 mg being recognized as the minimum effective dose. Research does not define explicit upper limits, though doses as high as 1600 mg have been safely used with no reported adverse effects. For optimal efficacy, ASI is best taken prior to physical or cognitive activities. It is available in both powder and capsule forms, with rapid absorption resulting in noticeable effects within 15 to 60 minutes post-ingestion.
FAQs
Is ASI safe to use?
Generally considered safe, ASI has not shown significant adverse effects, but individuals with health conditions should consult a healthcare professional.
When should I take ASI?
It is best taken before exercise or cognitive tasks to maximize its benefits.
What results can I expect from using ASI?
Users can expect improved blood flow, reduced muscle damage, and enhanced cognitive function.
Is ASI a substitute for a healthy lifestyle?
No, ASI should complement a healthy diet and regular exercise; results may vary individually.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859748/ – This study demonstrates the efficacy of inositol-stabilized arginine silicate in enhancing exercise performance and cognitive function through improved nitric oxide production, indicating moderate to high research quality.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308713/ – This review investigates various supplements designed to enhance athletic performance, including ASI, highlighting its safety profile and effectiveness in reducing muscle damage post-exercise.
Supplements Containing Nitrosigine Arginine Silicate Inositol
Outrage Watermelon
Nutrex Research
Outrage Blue Raspberry
Nutrex Research
Outrage Fruit Punch
Nutrex Research
Outrage Blackberry Lemonade
Nutrex Research
Mr Hyde Icon Pre Workout Poseidon Blueberry Lemon Wrath
PS ProSupps
Hyde Extreme Blue Razz Blitz
PS ProSupps