Neumentix Spearmint Aerial Part Extract
Also known as: Spearmint, Neumentix, Mentha spicata L. aerial part extract
Overview
Neumentix is a patented botanical extract derived from the aerial parts of Mentha spicata L. (spearmint) plants. It is standardized to contain at least 14.5% rosmarinic acid and 24% total phenolic content. Primarily utilized as a nootropic, Neumentix aims to enhance cognitive functions such as working memory, attention, and reaction time. Emerging research also suggests its potential to improve physical performance, particularly reactive agility. Clinical studies, including randomized controlled trials, support its efficacy and safety profile. While some studies are manufacturer-sponsored, they generally adhere to rigorous methodologies, contributing to a growing body of evidence for its benefits.
Benefits
Neumentix offers several evidence-based benefits, primarily in cognitive and physical performance. Randomized controlled trials (RCTs) have shown significant improvements in working memory, attention, planning, and reasoning after 30 to 90 days of supplementation with 900 mg/day. For instance, a 90-day RCT involving 142 healthy, recreationally active adults demonstrated improved choice reaction time and reactive agility, with effects observed as early as 7 days. Preclinical studies further suggest neuroprotective effects due to its antioxidant and anti-inflammatory properties, which likely contribute to its cognitive benefits. The extract is generally well-tolerated with no serious adverse events reported in clinical studies, indicating a favorable safety profile.
How it works
Neumentix exerts its effects primarily through its rich polyphenol content, particularly rosmarinic acid. These bioactive compounds act as potent antioxidants and anti-inflammatory agents within the brain. By reducing oxidative stress and inflammation, they protect neurons from damage and support overall neuronal health and growth. Furthermore, Neumentix is believed to modulate neurotransmitters crucial for learning and memory, thereby enhancing synaptic function and promoting neuroplasticity. The good bioavailability of its active compounds ensures they can reach and influence brain regions vital for cognitive processes and motor control, leading to improved mental and physical performance.
Side effects
Neumentix is generally considered safe and well-tolerated, with no significant adverse effects reported in clinical trials involving healthy adults at the recommended dosage of 900 mg/day. Common side effects are not reported at a frequency greater than 5%. To date, there have been no documented significant drug interactions or contraindications in the scientific literature. However, specific populations such as the elderly, pregnant women, or nursing mothers have not been extensively studied, and therefore, caution is advised for these groups. As with any supplement, individuals with pre-existing medical conditions or those taking prescription medications should consult a healthcare professional before starting supplementation.
Dosage
The effective dosage of Neumentix, as established in clinical trials, is 900 mg per day. This dosage refers to an extract standardized to contain 14.5% rosmarinic acid. The duration of supplementation in studies has ranged from as short as 7 days, where early effects on reaction time were observed, to 90 days for more chronic cognitive benefits. While 900 mg/day is the studied effective dose, a maximum safe dose beyond this amount has not been established, and higher doses have not been thoroughly investigated. Consistent daily intake is recommended for optimal results, though the specific timing of administration throughout the day does not appear to be critical.
FAQs
Is Neumentix safe for long-term use?
Current evidence supports its safety for up to 90 days of use. Longer-term safety data are limited, so continued research is needed.
How soon do benefits appear?
Improvements in reaction time can be observed within 7 days, while cognitive benefits typically become noticeable after 30 days of consistent supplementation.
Can it improve physical performance?
Yes, studies have shown that Neumentix can improve reactive agility in young, active adults, contributing to enhanced physical performance.
Does it interact with medications?
No known drug interactions have been documented, but clinical data on this aspect are limited. Consult a healthcare professional if taking medications.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6291964/ – This randomized, double-blind, placebo-controlled trial investigated the effects of Neumentix on cognitive and physical performance in 142 healthy, recreationally active adults over 90 days. It found that 900 mg/day of Neumentix significantly improved reactive agility and choice reaction time, with effects observed as early as 7 days. The study was well-powered and indicated a high quality of evidence.
- https://fortifeye.com/wp-content/uploads/KHTL-017-123-30-Day-Open-Label-Clinical-Study-Neumentix-Enhances-Acute-and-Chronic-Cognitive-Function.pdf – This open-label clinical study, though lacking a placebo control, explored the effects of Neumentix on cognitive function. It reported significant improvements in attention, planning, and reasoning, along with good tolerability. While preliminary, it provided early indications of cognitive benefits and safety.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10627303/ – This preclinical study, conducted in a rat model, investigated the neuroprotective effects of Neumentix. It demonstrated dose-dependent neuroprotective benefits on retinal ganglion cells, suggesting underlying antioxidant mechanisms. This research provides supportive mechanistic data for the cognitive benefits observed in human studies.