Super-Z-Lite All Natural Proprietary Blend
Also known as: Clinoptilolite zeolite, natural zeolite, PMA-zeolite, Super-Z-Lite All Natural Proprietary Blend, Clinoptilolite
Overview
Clinoptilolite is a naturally occurring zeolite mineral formed from volcanic ash altered by alkaline groundwater. It possesses a unique microporous aluminosilicate structure, which grants it significant ion-exchange and adsorption capabilities. Primarily utilized as a dietary supplement, its main applications revolve around detoxification, particularly the chelation of heavy metals and environmental toxins. It is also believed to support mineral balance and immune health. Key characteristics include its high adsorption capacity, ion-exchange properties, and chemical stability. For enhanced efficacy, it is often micronized to increase its surface area. The research supporting clinoptilolite's benefits is moderate, with several clinical trials and reviews available, though large-scale, high-quality randomized controlled trials are still limited. Evidence primarily stems from small clinical trials and preclinical studies, focusing on its safety and potential detoxification effects.
Benefits
Clinoptilolite's primary benefit is the detoxification of heavy metals and environmental toxins through its ion-exchange and adsorption properties. Studies, such as a 28-day trial using 6 g/day, have shown its ability to modulate mineral levels in healthy subjects, suggesting a potential improvement in mineral metabolism and blood parameters. While effect sizes are not consistently reported, these preliminary findings indicate a positive impact on the body's internal environment. Secondary benefits include suggested immunostimulatory and antioxidant properties, though these require further robust research for confirmation. The benefits are primarily observed in healthy adults, with limited data available for individuals with chronic diseases. The available studies are generally small (e.g., n=15), and while short-term changes in mineral metabolism have been noted within 28 days, the long-term effects remain unclear. The quality of evidence is moderate, with a need for larger, more comprehensive studies to solidify these claims.
How it works
Clinoptilolite functions primarily through physical-chemical processes rather than biochemical receptor binding. Its mechanism of action involves ion-exchange and adsorption, where its porous crystalline structure traps positively charged ions, such as heavy metals and various toxins. This action occurs predominantly within the gastrointestinal tract. By binding these harmful substances, clinoptilolite reduces their bioavailability and facilitates their excretion from the body, thereby preventing their systemic absorption. It does not have specific molecular targets but rather interacts with body systems by physically sequestering undesirable compounds. Crucially, clinoptilolite is not absorbed systemically into the bloodstream. Micronization, reducing particle size to below 14 microns, enhances its surface area and thus its adsorption capacity, optimizing its efficacy in the gut.
Side effects
Clinoptilolite is generally recognized as safe and has demonstrated a good safety profile in human studies. No significant common side effects (occurring in >5% of users) have been reported in clinical trials. Similarly, uncommon (1-5%) and rare (<1%) side effects, including serious adverse events, are not well documented. However, there is a theoretical risk of drug interactions, as clinoptilolite's adsorptive properties could potentially bind to orally administered medications, reducing their absorption and efficacy. Therefore, it is advisable to space out the intake of clinoptilolite from other medications. Contraindications include individuals with compromised renal function, due to the potential impact on mineral balance, and those already on mineral supplementation, as it could interfere with the absorption of beneficial minerals. Data on its safety in special populations, such as pregnant or lactating women, is limited, and caution is advised.
Dosage
Clinical studies have utilized a minimum effective dose of 6 g/day of clinoptilolite. This dosage, taken orally, appears effective in short-term studies, with observed changes in mineral metabolism within 28 days. However, there is no established consensus on optimal long-term dosing, nor is a maximum safe dose well-established beyond the 6 g/day for 28 days that has been shown to be safe. The timing of intake relative to meals or other medications is not well defined, but due to its adsorptive properties, it is generally recommended to take it separately from medications to avoid potential interactions. For optimal efficacy, micronized forms (particle size below 14 microns) are recommended, as they offer a greater surface area for adsorption. Clinoptilolite is not systemically absorbed; its effectiveness relies on its purity and particle size. It is sometimes combined with fulvic and trace minerals, which are considered cofactors to enhance overall mineral balance.
FAQs
Is Super-Z-Lite safe?
Yes, based on current evidence, clinoptilolite, the active ingredient in Super-Z-Lite, is generally considered safe with minimal reported side effects in clinical studies.
How quickly does it work?
Some changes in mineral metabolism have been observed within 28 days of supplementation, indicating a relatively short-term onset of effects.
Can it remove heavy metals?
Yes, clinoptilolite is known to adsorb heavy metals in the gastrointestinal tract, facilitating their excretion from the body.
Does it get absorbed into the body?
No, clinoptilolite acts locally within the gut and is not absorbed systemically into the bloodstream.
Are there any interactions with medications?
There's a potential for clinoptilolite to reduce the absorption of orally administered medications if taken simultaneously; spacing out intake is recommended.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9197155/ – This clinical trial investigated the effects of 6 g/day of PMA-zeolite (clinoptilolite) in 15 healthy adults over 28 days. The study found that supplementation modulated mineral metabolism and blood parameters without causing adverse effects. However, the small sample size and short duration limit the generalizability of these findings.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6277462/ – This critical review assessed the safety and medical applications of clinoptilolite. It concluded that clinoptilolite is safe and potentially effective for detoxification and immunostimulation, based on various in vivo and in vitro studies. The review highlighted the need for further large-scale randomized controlled trials to confirm these benefits.
- https://www.cir-safety.org/sites/default/files/Zeolites.pdf – This systematic safety assessment by the Cosmetic Ingredient Review (CIR) panel evaluated zeolites, including clinoptilolite. The assessment confirmed the safety of clinoptilolite in both dermal and oral applications, reporting no significant toxicity. This supports its general safety profile for human use.
- https://omicaorganics.com/products/super-z-lite-liquid-zeolite-2oz – This commercial product page for Super-Z-Lite Liquid Zeolite highlights the benefits of micronized clinoptilolite, emphasizing its enhanced surface area for adsorption. It suggests that micronization improves the efficacy of the zeolite for detoxification, though independent clinical trials specifically on this proprietary blend are not provided.
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