Muira Pauma
Also known as: Ptychopetalum olacoides, Muira Puama, potency wood, marapuama
Overview
Muira Puama, scientifically known as *Ptychopetalum olacoides*, is a plant native to the Amazon rainforest, particularly Brazil. It has a history of traditional use in Amazonian folk medicine, primarily as an aphrodisiac to enhance sexual desire and function in both men and women. It has also been used for menstrual disorders and joint pain. The supplement is derived from the wood and root of the plant. However, scientific understanding of its active compounds and mechanisms is limited. Research on Muira Puama is sparse, with few high-quality human clinical trials. Most available studies are small or animal-based, with a lack of rigorous randomized controlled trials (RCTs) in humans. More research is needed to fully understand its effects and safety profile.
Benefits
Limited evidence suggests Muira Puama may improve sexual desire and function. One study involving 202 postmenopausal women using a supplement containing Muira Puama and Ginkgo biloba reported that 65% of participants experienced increased frequency and intensity of sexual thoughts and improved ability to achieve orgasm. However, this study combined Muira Puama with other ingredients, complicating attribution of effects solely to Muira Puama. Animal studies combining Muira Puama with other substances (L-citrulline, ginger, *Paullinia cupana*) showed improvements in age-related erectile function comparable to PDE5 inhibitors in rats. Claims for benefits in joint pain, menstrual disorders, and general vitality lack robust clinical evidence.
How it works
The exact biological mechanisms of Muira Puama are not well understood. Animal studies suggest it may influence nitric oxide synthase (NOS) expression, which plays a role in erectile function. No definitive molecular targets or pathways have been identified in humans. The active chemical constituents responsible for effects remain unclear. Further research is needed to elucidate its mechanism of action and identify the active compounds responsible for its purported effects.
Side effects
Muira Puama is considered possibly safe when taken orally at doses of 500–1050 mg daily for up to one month. There is insufficient data on common or rare side effects due to limited human studies. No significant adverse effects have been consistently reported in short-term use. Safety during pregnancy and breastfeeding is unknown; use is not recommended in these groups. No well-documented drug interactions exist, but caution is advised due to lack of data. Long-term safety data is lacking, and potential risks associated with prolonged use are unknown.
Dosage
Typical doses used in studies range from 500 to 1050 mg daily, often as part of multi-ingredient supplements. Optimal dosing and duration are not established due to limited clinical trials. No data on maximum safe doses or long-term safety exists. Absorption and bioavailability data are lacking. Due to the limited research, it is important to consult with a healthcare professional before using Muira Puama to determine the appropriate dosage and ensure safety.
FAQs
Is Muira Puama effective for erectile dysfunction?
Current human evidence is insufficient to support its use as a standalone treatment for ED. More research is needed to determine its efficacy.
Can it increase libido?
Some evidence from combined supplement studies suggests potential benefit, but isolated effects of Muira Puama are unclear. Further studies are needed to confirm this.
Is it safe to use long-term?
Safety beyond one month is not established. Consult with a healthcare professional before using it long-term.
Are there known side effects?
No common side effects have been reported in short-term use, but data are limited. Monitor for any adverse reactions.
Should it be used during pregnancy?
Avoid use due to lack of safety data. Consult with a healthcare professional for alternatives.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7340557/ – This review discusses various herbal aphrodisiacs and their potential mechanisms of action. It mentions Muira Puama as a traditional medicine used for sexual dysfunction, but notes the limited evidence supporting its efficacy compared to other well-studied herbs.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10490034/ – This article reviews the use of herbal medicines for the treatment of erectile dysfunction. While it doesn't focus solely on Muira Puama, it provides context on the broader landscape of herbal remedies used for sexual health and highlights the need for more rigorous clinical trials.
- https://www.sciencedirect.com/science/article/abs/pii/S0963996911001451 – This study investigates the effects of a multi-ingredient supplement containing Muira Puama on sexual function in postmenopausal women. The results suggest potential benefits, but the combination of ingredients makes it difficult to isolate the specific effects of Muira Puama.
- http://sif2022-production.s3.amazonaws.com/uploads/attachment/file_it/1788/Borrelli_2018_Drugs.pdf – This review provides an overview of herbal dietary supplements and their potential interactions with drugs. It emphasizes the importance of considering potential interactions when using herbal supplements, especially in combination with prescription medications.
- https://www.webmd.com/vitamins/ai/ingredientmono-574/muira-puama – WebMD provides general information about Muira Puama, including its uses, potential side effects, and dosage recommendations. It serves as a basic overview but should be supplemented with more rigorous scientific sources.
