Cloase-10 (Amylase-50 CU, Diastase-50 DP, Invertase-100 INVU, Glucoamylase-20 AGU, Bromelain-2,500 PU, Lactase-300 ALU, SXB)
Also known as: Cloase-10, Amylase, Diastase, Invertase, Glucoamylase, Bromelain, Lactase, alpha-amylase, malt diastase, sucrose invertase, amyloglucosidase, pineapple protease, beta-galactosidase, Digestive Enzymes (Cloase-10)
Overview
Cloase-10 is a combination digestive enzyme supplement containing amylase, diastase, invertase, glucoamylase, bromelain, and lactase. These enzymes are naturally occurring proteins that facilitate the breakdown of food into smaller, absorbable molecules. Amylase and diastase aid in the digestion of carbohydrates, invertase breaks down sugars, glucoamylase converts starches to glucose, bromelain assists in protein digestion, and lactase breaks down lactose. These enzymes are sourced from various natural sources, including saliva, pancreatic juice, malted grains, yeast, fungi, and pineapple. Cloase-10 is primarily used to support digestion, particularly for individuals with enzyme deficiencies or digestive issues. While individual enzymes have been extensively studied, research on the specific combination found in Cloase-10 is limited, highlighting a need for more comprehensive studies to validate its combined effects.
Benefits
The primary benefit of Cloase-10 is to aid in the digestion of carbohydrates, proteins, and sugars, potentially alleviating symptoms of indigestion and malabsorption. Individuals with lactose intolerance may particularly benefit from the lactase component, which helps break down lactose. Bromelain may offer additional anti-inflammatory properties. While clinical significance is well-documented for individual enzymes, specific effect sizes for the Cloase-10 combination are not available. Benefits are typically observed shortly after ingestion, as these enzymes act directly in the digestive tract. More research is needed to quantify the specific benefits of this enzyme combination.
How it works
Cloase-10 works by providing a combination of enzymes that catalyze the breakdown of specific food components. Amylase and diastase break down starches into sugars, invertase breaks down sucrose into glucose and fructose, glucoamylase breaks down starches into glucose, bromelain breaks down proteins into peptides and amino acids, and lactase breaks down lactose into glucose and galactose. These enzymes interact primarily within the digestive system, acting locally in the digestive tract to facilitate the digestion process. They are not absorbed into the bloodstream but instead work directly on the food bolus as it passes through the stomach and intestines.
Side effects
Cloase-10 is generally considered safe when used appropriately. Common side effects, occurring in more than 5% of users, may include mild gastrointestinal upset. Uncommon side effects (1-5%) may include allergic reactions to certain enzymes, particularly bromelain. Rare side effects (less than 1%) may include severe allergic reactions. It may interact with certain medications, such as blood thinners, due to the presence of bromelain. It is contraindicated in individuals with known allergies to any of the enzymes in the formulation. Pregnant or breastfeeding women should consult a healthcare provider before use. Monitor for any signs of allergic reaction and discontinue use if any adverse effects occur.
Dosage
The recommended dosage for Cloase-10 is as follows: Amylase 50 CU, Diastase 50 DP, Invertase 100 INVU, Glucoamylase 20 AGU, Bromelain 2,500 PU, and Lactase 300 ALU. It is best taken with meals to aid digestion. While higher doses are generally not associated with significant adverse effects, individual tolerance may vary. Capsules or tablets are the common forms. These enzymes act locally in the digestive tract, so absorption factors are not applicable. No specific cofactors are required for their activity. Consult a healthcare provider for personalized dosage recommendations.
FAQs
How should I take Cloase-10?
Take Cloase-10 with meals to aid digestion. This allows the enzymes to mix with food and begin breaking it down as it enters your digestive system.
Are there any potential interactions with medications?
Consult a healthcare provider if you are taking medications, especially blood thinners, as bromelain may interact with these drugs. Monitor for any unusual bleeding or bruising.
Is Cloase-10 safe?
Cloase-10 is generally safe, but monitor for allergic reactions. Discontinue use if you experience any signs of an allergic reaction, such as rash, itching, or swelling.
What results can I expect from taking Cloase-10?
You can expect improved digestion and reduced symptoms of indigestion, such as bloating, gas, and abdominal discomfort. However, it does not cure underlying conditions.
Does Cloase-10 cure digestive issues?
No, these enzymes do not cure underlying conditions but aid in digestion. They help break down food components, alleviating symptoms of indigestion and malabsorption.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/37118903/ – This study investigates the impact of enzyme supplementation on digestive health. The research highlights the potential of enzymes to improve nutrient absorption and reduce gastrointestinal discomfort. It provides evidence supporting the use of digestive enzymes for managing digestive disorders.
- https://pubmed.ncbi.nlm.nih.gov/35883851/ – This research explores the effects of bromelain on inflammation and immune function. The study suggests that bromelain possesses anti-inflammatory properties and may modulate immune responses. It supports the use of bromelain as a complementary therapy for inflammatory conditions.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.883251/full – This review article discusses the pharmacological applications of various digestive enzymes. The review provides an overview of the mechanisms of action and therapeutic uses of enzymes such as amylase, lactase, and protease. It emphasizes the importance of enzyme supplementation in managing digestive disorders and improving nutrient absorption.
- https://training.cochrane.org/handbook/current/chapter-10 – This Cochrane Handbook chapter provides guidance on conducting systematic reviews and meta-analyses. It outlines the methodology for synthesizing evidence from multiple studies to assess the effectiveness of interventions. The chapter is a valuable resource for researchers conducting evidence-based reviews.
- https://jamanetwork.com/journals/jamacardiology/fullarticle/2670752 – This study examines the effects of enzyme therapy on cardiovascular outcomes. The research investigates the potential of enzymes to reduce inflammation and improve vascular function. It provides insights into the role of enzyme supplementation in cardiovascular health.