Floraglo
Also known as: FloraGLO, lutein, lutein ester, marigold extract, Lutein
Overview
Lutein is a carotenoid found abundantly in dark green leafy vegetables, such as spinach and kale, as well as in marigold flowers. FloraGLO is a specifically branded form of lutein derived from these flowers, known for its high bioavailability and unesterified form. It has gained recognition primarily for its role in eye health, particularly in reducing the risk of age-related macular degeneration (AMD) through enhancing macular pigment optical density (MPOD). Research indicates that regular lutein supplementation can lead to significant improvements in eye health, visual acuity, and contrast sensitivity. Moreover, there is emerging evidence that lutein may also support cognitive function and skin health, making it a versatile supplement for various populations experiencing low intake of dietary carotenoids.
Benefits
The primary benefit of lutein, particularly FloraGLO, is its positive impact on eye health, with strong evidence indicating that it can increase MPOD, thereby reducing the risk of AMD. A meta-analysis showed that greater dietary intake of lutein is associated with a significant reduction in AMD risk. Secondary benefits include potential support for cognitive function, especially in aging populations, though this area requires further investigation. Additionally, lutein has been noted for improving skin hydration and elasticity. The evidence demonstrates clinically significant improvements in visual functions, with measurable effects observed within 2-4 months of consistent supplementation.
How it works
Lutein functions primarily as an antioxidant and a blue light filter, which helps to protect the macula from oxidative stress. By accumulating in the macula, lutein increases the pigment density there, which is crucial for enhancing visual acuity and overall eye health. The mechanism of action involves the absorption of blue light wavelengths that can be damaging to retinal tissues, thereby also providing protection to other body systems. The bioavailability of lutein is significantly increased when included in meals containing fats, facilitating its absorption into the body.
Side effects
Lutein is generally recognized as safe (GRAS) and is well-tolerated, with no common adverse effects reported at typical supplementation dosages. There are no uncommon or rare side effects documented in clinical studies. No significant drug interactions or contraindications are known, making it safe for most individuals across various life stages, including infants and young children. While it is considered safe for general use, individuals should always consult with a healthcare provider prior to starting any new supplement regimen, particularly if they are pregnant, nursing, or have underlying health conditions.
Dosage
The minimum effective dose of lutein for eye health benefits is approximately 10 mg per day, with optimal intake suggested to be between 10-20 mg daily. The maximum safe dose has been established at 2 mg/kg of body weight according to known safety assessments. Timing is noted to be crucial for absorption; lutein should ideally be consumed with meals containing fats to enhance bioavailability. Various formulation forms are available, including capsules and liquid supplements, which should be chosen based on individual preference. Regular dosing over a period of several months may be necessary to observe the full benefits.
FAQs
Should I take lutein with food?
Yes, lutein is best absorbed when taken with meals containing fats.
Is lutein safe for everyone?
Yes, lutein is generally safe for almost all populations, including children, but consult a healthcare provider before starting.
How long does it take to see benefits from lutein?
Improvements in eye health can be noticed after 2-4 months of consistent supplementation.
Can lutein cure eye diseases?
No, lutein cannot cure existing eye diseases but may help prevent their progression.
What if I miss a dose?
If you miss a dose, take it as soon as you remember unless it's almost time for the next dose.
Research Sources
- https://info.kemin.com/hubfs/KH/FloraGLO_Whitepaper.pdf – This whitepaper discusses the benefits of FloraGLO Lutein, particularly its impact on eye health, backed by clinical observations and studies targeting macular degeneration.
- https://www.mdpi.com/2072-6643/12/5/1321 – This peer-reviewed study reflects on the relationship between lutein intake and eye health, demonstrating significant correlations with MPOD and visual enhancements.
- https://ctv.veeva.com/study/evaluation-of-the-benefits-of-floraglo-lutein-on-skin-health – Research evaluating the effects of FloraGLO on skin hydration and elasticity showcases its potential secondary health benefits, particularly for skin health.
- https://www.researchgate.net/publication/379584251_Effect_of_Antioxidant_Supplementation_on_Macular_Pigment_Optical_Density_and_Visual_Functions_A_systematic_review_and_network_meta-analysis_of_randomized_controlled_trials – This systematic review analyzes various randomized controlled trials, reaffirming lutein's significant role in enhancing MPOD and overall visual function.
- https://www.nutraceuticalsworld.com/breaking-news/maternal-lutein-zeaxanthin-supplementation-linked-to-improved-carotenoid-levels-in-children-study/ – This study highlights maternal supplementation of lutein and zeaxanthin, linking it to improved carotenoid levels in children, emphasizing the nutrient's importance across different life stages.