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Lemon Myrtle

Also known as: Lemon Myrtle, Sweet Verbena Tree, *Backhousia citriodora*

Overview

Lemon myrtle is a plant native to Australia, recognized for its distinct citrus aroma and array of health benefits attributed to its essential oil and extracts. Traditionally used in native Australian medicine, lemon myrtle exhibits notable properties such as antimicrobial, anti-inflammatory, and antioxidant effects. These attributes make it a candidate for treating various conditions, including infections and wounds, and its potential anti-cancer properties have been highlighted in some studies. The majority of current research centers on in vitro studies and small-scale human trials, indicating a moderate level of research maturity. While several promising outcomes have been reported, further extensive, controlled studies are necessary to validate these effects and solidify its therapeutic applications.

Benefits

Evidence indicates that lemon myrtle extract may enhance muscle hypertrophy when combined with resistance training, particularly benefiting older adults. One notable study observed a significant 7.4% increase in muscle thickness over six weeks among participants supplementing with 250 mg daily compared to placebo. Additionally, it has demonstrated in vitro anti-cancer activity and is noted for its anti-inflammatory and antioxidant properties. These secondary effects may help in reducing oxidative stress and inflammation, providing potential health benefits in mitigating conditions associated with aging. Nonetheless, the strength of evidence remains variable, with many studies being limited in scope, underscoring the need for more robust research.

How it works

The active constituents of lemon myrtle, such as citrals and casuarinin, are believed to play a key role in its action. These compounds may activate muscle satellite cells, promoting muscle hypertrophy through pathways that involve the modulation of inflammation and cancer cell proliferation. Lemon myrtle is also thought to interact with various biological systems; for instance, enhancing growth in the musculoskeletal system while potentially exerting anti-inflammatory effects on the immune system. Known molecular targets include APEX1, androgen receptors, and cyclin-dependent kinases.

Side effects

Lemon myrtle is generally considered safe for use when taken in appropriate doses. A clinical trial indicated no significant adverse effects for older adults consuming 250 mg of lemon myrtle extract daily for 12 weeks. However, detailed documentation on side effects is limited due to the relatively small body of research involving humans. Currently, no specific contraindications, drug interactions, or severe side effects have been identified. Special considerations should be made for pregnant and breastfeeding individuals, as comprehensive safety data is lacking in these populations. Caution is recommended, and it is advised to consult healthcare providers when considering supplementation, particularly for those with underlying health conditions.

Dosage

The typical dosage of lemon myrtle extract ranges from 250 mg daily, based on findings from a small-scale study that reported positive outcomes in muscle growth when used in conjunction with resistance training. While optimal ranges for other health benefits remain unidentified, no upper safety limits have been established either. Users are not provided with specific timing recommendations for intake. Lemon myrtle is available in both extract and essential oil forms, with no noted absorption factors impacting its efficacy as of yet. More information on required cofactors or dosage specifics for various conditions is currently unavailable.

FAQs

What can lemon myrtle be used for?

Lemon myrtle is primarily used for potential muscle enhancement, as well as anti-inflammatory and antioxidant support. It may also have antibacterial and anti-cancer benefits.

Is lemon myrtle safe to use?

Generally, lemon myrtle is considered safe when used appropriately. Limited human studies suggest minimal adverse effects, but further research is needed.

When should I take lemon myrtle?

There are no specific timing recommendations for lemon myrtle supplementation; however, daily doses of 250 mg are noted for best results related to muscle hypertrophy.

What results can I expect from lemon myrtle?

Potential results include enhanced muscle growth, along with anti-inflammatory and antioxidant effects, particularly beneficial for older adults.

Can lemon myrtle cure cancer?

Lemon myrtle is not a cure for cancer and should not replace conventional medical treatments; its anti-cancer properties have been noted primarily in preliminary studies.

Research Sources

https://ffhdj.com/index.php/ffhd/article/view/1472 – This randomized controlled trial involved 14 older adults taking lemon myrtle extract, observing significant increases in muscle hypertrophy after six weeks of resistance training.
https://pubmed.ncbi.nlm.nih.gov/37054823/ – Examined the in vitro anti-cancer activity of lemon myrtle essential oil, highlighting its potential mechanisms, although results may not directly apply to human health.
https://ffhdj.com/index.php/ffhd/article/download/1472/4139/10484 – A study demonstrating lemon myrtle's antioxidant and anti-inflammatory properties via in vitro methods, urging for more comprehensive human trials to affirm these findings.
https://pubmed.ncbi.nlm.nih.gov/32071880/ – Investigated the active compounds in lemon myrtle, discussing their potential roles in muscle activation and therapeutic effects, but highlighted the necessity for larger-scale studies.
https://www.researchgate.net/publication/359062664_Lemon_Myrtle_Backhousia_citriodora_Extract_and_Its_Active_Compound_Casuarinin_Activate_Skeletal_Muscle_Satellite_Cells_In_Vitro_and_In_Vivo – Thisresearch focuses on the activation of muscle satellite cells by casuarinin found in lemon myrtle, establishing a potential link between the extract's properties and muscle growth.