Lemon Balm Supercritical Extract
Also known as: Melissa officinalis, balm mint, bee balm, common balm, Lemon Balm
Overview
Lemon balm (*Melissa officinalis* L.) is a perennial herb from the mint family, native to Europe and the Mediterranean. Known historically for its calming effects, it serves as a digestive aid and is rich in bioactive compounds like rosmarinic acid. Lemon balm is recognized in herbal medicine for its potential benefits in treating anxiety, depression, sleep disorders, dyslipidemia, and cardiovascular issues. Recent clinical trials have provided varying degrees of support for these applications, indicating a need for further robust research to validate its effectiveness across diverse populations. The extract is typically available in various forms, including capsules, teas, and tinctures, and is particularly valued for its therapeutic properties.
Benefits
Research through systematic reviews and meta-analyses reveals significant benefits of lemon balm, especially in improving anxiety (standardized mean difference [SMD] -0.98) and depression (SMD -0.47) symptoms compared to placebo. Additional advantages include reductions in triglycerides (SMD -0.396), total cholesterol (SMD -0.416), and LDL cholesterol (SMD -0.23). Moreover, antifungal effects against certain *Fusarium* species have been reported. Individuals suffering from anxiety, depression, and abnormal lipid profiles often experience the most notable improvements. Although the evidence supports these benefits, variability in study quality warrants careful interpretation of the findings.
How it works
The therapeutic effects of lemon balm primarily stem from its bioactive compounds, especially rosmarinic acid. This compound interacts predominantly with neurotransmitter systems, particularly modulating the GABA system, which contributes to its anxiolytic and antidepressant effects. Additionally, lemon balm appears to influence lipid metabolism pathways, thus improving lipid profiles. These interactions signify potential benefits for both the central nervous system and cardiovascular health, although the specific molecular targets and pathways involved require further elucidation.
Side effects
Overall, lemon balm is considered safe with minimal side effects documented in clinical studies. Common side effects exceeding 5% occurrence have not been reported, while some uncommon (1-5%) and rare (<1%) side effects remain insufficiently documented. When used alongside CNS depressants or lipid-lowering medications, caution is warranted due to possible interactions. Pregnant and breastfeeding women are advised to exercise caution with lemon balm due to limited safety research in these populations. Despite its strong overall safety profile, individual responses may vary, and awareness of potential interactions is critical.
Dosage
Dosage recommendations for lemon balm can vary depending on the intended use; clinical trials generally suggest doses ranging from 300 mg to 1,600 mg per day. The most commonly effective daily doses in studies are between 500 mg and 1,000 mg. No established upper limit is defined, but doses up to 1,600 mg have shown good tolerance without significant adverse effects. The timing of intake is flexible, although adherence to healthcare provider guidance is encouraged. Supercritical extracts may offer enhanced bioavailability, indicating a need for more research into optimal dosage and absorption.
FAQs
How often should I take lemon balm?
It's best to follow the dosage instructions provided by a healthcare provider or as indicated on the product label.
Can I take lemon balm with other medications?
Caution is advised when taking lemon balm with CNS depressants or lipid-lowering medications.
What are the expected results?
Users may experience reduced anxiety and depression symptoms, alongside improvements in lipid profiles.
Is lemon balm safe for everyone?
While generally safe, pregnant or breastfeeding women should use it with caution due to limited research.
What are the potential side effects?
Minimal side effects have been reported in clinical trials, indicating a favorable safety profile.
