Lactobacillus Rhamnosus Mak79l08r
Also known as: *Lactobacillus rhamnosus*, Mak79l08r, LGG (Lactobacillus rhamnosus GG), *Lactobacillus rhamnosus* Mak79l08r
Overview
Lactobacillus rhamnosus is a well-known species of lactic acid bacteria prevalent in the human gut and fermented foods. This specific strain, Mak79l08r, falls under the broader category of probiotic bacteria. Generally, probiotics, including L. rhamnosus, are lauded for their potential to enhance gut health and bolster the immune system. While there is extensive research supporting the benefits of several L. rhamnosus strains, specific studies focusing on Mak79l08r are limited. Existing literature emphasizes the species' role in gut flora improvement and immune modulation, with moderate to high-quality evidence for general health benefits.
Benefits
Lactobacillus rhamnosus strains, particularly LGG, have demonstrated several evidence-backed benefits. Notably, they can reduce the incidence of antibiotic-associated diarrhea, particularly in children. This effect is derived from a meta-analysis involving 1499 participants. Furthermore, these strains are associated with a reduction in atopic eczema occurrences, supported by a systematic review and meta-analysis featuring 11 randomized controlled trials. Evidence for specific benefits of the Mak79l08r strain remains lacking; however, general benefits for pediatric populations primarily aid in gut health and immune function. Overall, improvements may become evident within weeks to months of consistent probiotic use.
How it works
Lactobacillus rhamnosus exerts its effects primarily by modulating the gut microbiota, improving intestinal barrier function, and influencing immune responses. These probiotics promote a healthy balance of gut flora and can help inhibit the growth of pathogenic bacteria. Although specific molecular targets for the strain Mak79l08r are not identified, the general mechanism involves enhancing the immune response and restoring gut health, leading to overall improved gut function.
Side effects
Lactobacillus rhamnosus, including its various strains, is typically regarded as safe for most populations. Common side effects, occurring in more than 5% of users, include mild gastrointestinal symptoms such as bloating, gas, and possible changes in bowel habits. Uncommon side effects have not been well documented specifically for the Mak79l08r strain, while rare serious adverse events, such as infections, may occur in immunocompromised individuals. Drug interactions are generally insignificant, although it is recommended that immunocompromised patients consult a healthcare provider before use. Special caution is advised for critically ill patients, as they may be at increased risk.
Dosage
For effective probiotic use, *Lactobacillus rhamnosus* strains are commonly administered in doses ranging from 1 to 10 billion CFU per day. Specific recommendations for the Mak79l08r strain are currently unspecified. Probiotics are best consumed with food to enhance their survival through the acidic environment of the stomach, aiding in gut colonization. While there are no established maximum safe doses for Mak79l08r, adherence to recommended dosages is advised for optimal safety and effectiveness.
FAQs
How should I store *Lactobacillus rhamnosus* Mak79l08r?
Probiotics should be stored in a cool, dry place, preferably refrigerated, to maintain their viability.
Is it safe to take probiotics if I am immunocompromised?
While generally safe, consult your healthcare provider before starting probiotics if you are immunocompromised.
When is the best time to take probiotics?
Probiotics are best taken with meals to aid in their survival through stomach acidity.
What results can I expect from using this probiotic?
Results vary; benefits may become noticeable within weeks to months depending on individual health status.
Can probiotics cure medical conditions?
Probiotics are not a cure-all and their efficacy can vary; they support health but should not replace medical treatments.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/26365389/ – This meta-analysis examined the effectiveness of L. rhamnosus LGG in preventing antibiotic-associated diarrhea, demonstrating a significant reduction of cases among children. Overall, the evidence quality was assessed as moderate to low.
- https://pubmed.ncbi.nlm.nih.gov/36161401/ – This systematic review analyzed data from 11 randomized controlled trials on L. rhamnosus LGG and its effect on preventing atopic eczema in pediatric populations, indicating a meaningful reduction in incidence, albeit with high attrition rates affecting evidence quality.
- https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2021.727127/full – A systematic review regarding the role of L. rhamnosus LGG in enhancing tolerance in children with cow's milk allergy. It highlighted moderate quality evidence and discussed various biases and confounding factors that could affect results.
- https://pubmed.ncbi.nlm.nih.gov/39263298/ – An evaluation of the overall safety and efficacy of probiotics, including strains such as L. rhamnosus, reinforcing their potential benefits and side effects, while discussing their role in gut health.
- https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00124/full – This article provides insight into the clinical applications of probiotics like L. rhamnosus, discussing their safety profiles and effectiveness across various medical conditions.
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