Lactobacillus Plantarum 6595
Also known as: Lactiplantibacillus plantarum 6595, Lactobacillus plantarum 6595, Probi® Plantarum 6595
Overview
*Lactiplantibacillus plantarum* 6595, formerly *Lactobacillus plantarum* 6595, is a probiotic bacterium often found in fermented foods like kimchi and sauerkraut. As a dietary supplement, it is used to promote gut health and immune function. This strain is characterized by its ability to survive passage through the gastrointestinal tract and adhere to intestinal cells via a mannose-dependent mechanism, enhancing its bioavailability. While research on *L. plantarum* strains is fairly robust, specific evidence for the 6595 strain is derived mostly from observational and smaller-scale studies. Overall, *L. plantarum* 6595 is considered a probiotic supplement with potential benefits for gut health and immune support, though more targeted research is needed to fully elucidate its effects.
Benefits
*Lactiplantibacillus plantarum* 6595 is primarily recognized for its support of gut health and immune function. Research indicates that *Lactobacillus plantarum* strains can modulate cytokine levels, potentially reducing inflammation. While specific data for the 6595 strain is limited, some studies suggest it may aid in weight management and improve immune response. These benefits are generally observed within days to weeks of supplementation. The evidence supporting these benefits is moderate, with most studies being observational or small-scale. Individuals seeking to enhance gut health and immunity may find this supplement beneficial, but more high-quality studies are needed to confirm these effects.
How it works
*Lactiplantibacillus plantarum* 6595 primarily modulates the immune response by influencing cytokine production, such as TNF-α, IL-4, and IL-10. Its interaction with the body mainly involves the gastrointestinal and immune systems. A key aspect of its mechanism is its ability to adhere to intestinal cells via mannose-dependent binding, which enhances its bioavailability and effectiveness. By surviving passage through the GI tract and adhering to intestinal cells, *L. plantarum* 6595 can exert its beneficial effects on gut health and immune modulation.
Side effects
*Lactiplantibacillus plantarum* 6595 is generally considered safe for most individuals. Common side effects are typically mild and gastrointestinal in nature, including bloating and gas. Uncommon side effects may include allergic reactions or a worsening of underlying conditions. In rare cases, there is a risk of infection, particularly in immunocompromised individuals. It may interact with immunosuppressive drugs, and is generally contraindicated in severely immunocompromised individuals. Pregnant or breastfeeding women should exercise caution due to limited data. Overall, while *L. plantarum* 6595 is relatively safe, it's important to be aware of potential side effects and contraindications, especially for those with compromised immune systems.
Dosage
While a minimum effective dose is not well-established specifically for *Lactiplantibacillus plantarum* 6595, typical probiotic dosages range from 1-10 billion CFU per day. The maximum safe dose has not been definitively established, but it is generally considered safe within typical probiotic dosage ranges. It is best taken with food to enhance its survival through the GI tract. Common forms include capsules and fermented foods. Its absorption is enhanced by its ability to adhere to intestinal cells. No specific cofactors are required for its function.
FAQs
How should I store *Lactiplantibacillus plantarum* 6595?
Store in a cool, dry place to maintain its viability and effectiveness as a probiotic supplement.
Is *Lactiplantibacillus plantarum* 6595 safe for everyone?
It is generally safe, but individuals who are immunocompromised should consult a healthcare provider before use.
When is the best time to take *Lactiplantibacillus plantarum* 6595?
It is best taken with meals to enhance its survival and effectiveness in the gastrointestinal tract.
What results can I expect from taking *Lactiplantibacillus plantarum* 6595?
You can expect improved gut health and enhanced immune function with regular use as a supportive supplement.
Is *Lactiplantibacillus plantarum* 6595 a cure for diseases?
No, it is not a cure for diseases but rather a supportive supplement that can aid in gut health and immune function.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/39062848/ – This study investigates the impact of *Lactobacillus plantarum* on gut microbiota composition and metabolic profiles in mice. The findings suggest that *L. plantarum* supplementation can significantly alter the gut microbiome, leading to improved metabolic health. This research provides insights into the potential of *L. plantarum* as a probiotic intervention for metabolic disorders.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6391266/ – This review discusses the role of *Lactobacillus plantarum* in various health conditions, including gastrointestinal disorders and immune modulation. It highlights the strain's ability to produce antimicrobial substances and its potential to enhance the gut barrier function. The review emphasizes the need for further research to fully understand the clinical applications of *L. plantarum*.
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.643420/full – This article explores the immunomodulatory effects of *Lactobacillus plantarum* on cytokine production. The study demonstrates that *L. plantarum* can influence the balance of pro-inflammatory and anti-inflammatory cytokines, supporting immune function. These findings suggest a potential role for *L. plantarum* in managing inflammatory conditions.
- https://microbiomepost.com/probiotic-strains/lactiplantibacillus-plantarum-6595/ – This resource provides an overview of *Lactiplantibacillus plantarum* 6595, highlighting its probiotic properties and potential health benefits. It emphasizes the strain's ability to survive the gastrointestinal tract and adhere to intestinal cells. The article suggests that *L. plantarum* 6595 can contribute to gut health and immune support.
- https://patents.google.com/patent/US9687513B2/en – This patent describes a specific strain of *Lactobacillus plantarum* and its application in promoting gut health and immune function. The patent details the strain's unique characteristics and its potential use in dietary supplements and functional foods. It highlights the strain's ability to improve gut microbiota composition and enhance immune response.
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