Lactobacillus Helveticus R0052nd
Also known as: Lactobacillus helveticus, L. helveticus R0052, Probiotic R0052, Lactobacillus helveticus R0052
Overview
*Lactobacillus helveticus* R0052 is a specific strain of lactic acid bacteria predominantly found in fermented dairy products such as yogurt and cheese, as well as in the human gastrointestinal tract. Renowned for its probiotic properties, this strain can survive stomach acidity, adhere to intestinal cells, and prevent pathogenic bacteria multiplication. Clinical studies have substantiated its role in managing gastrointestinal issues, particularly in eradicating *Helicobacter pylori*, alleviating antibiotic-associated diarrhea, and promoting gut health. The strain possesses the ability to maintain epithelial integrity and balance gut microbiota, thus enhancing overall gut functionality. Its efficacy has been demonstrated through robust research, including in vitro studies and human clinical trials, confirming its safety and functional benefits as a dietary supplement.
Benefits
[{"benefit":"Helicobacter pylori Eradication","evidence_strength":"High","description":"Combination use of *L. helveticus* R0052 with *L. rhamnosus* R0011 increased eradication rates of *H. pylori* (90.9% vs 75.0%, p = 0.047), while also reducing treatment side effects."},{"benefit":"Reduction of Antibiotic-Associated Diarrhea (AAD)","evidence_strength":"High","description":"Supplementation effectively reduced the duration of AAD in individuals taking antibiotics like amoxicillin-clavulanic acid."},{"benefit":"Seizure Susceptibility Management","evidence_strength":"Moderate","description":"Increased seizure thresholds were observed in mice, suggesting potential benefits in seizure management through short-chain fatty acid production."},{"benefit":"Immune Modulation","evidence_strength":"Moderate","description":"*L. helveticus* R0052 can stimulate immune responses and improve gut microbiota composition."},{"benefit":"Gut Health","evidence_strength":"Moderate","description":"Promotes a balance of beneficial bacteria in the gut."}]
How it works
*Lactobacillus helveticus* R0052 functions by modulating the immune system through direct interactions with immune cells, enhancing both local and systemic immune responses. It produces lactic acid and bacteriocins that inhibit pathogenic bacteria and maintain a healthy microbiotal balance. Furthermore, this strain enhances gut barrier integrity and supports the viability of beneficial bacteria by adhering to gut epithelial cells, thereby preventing harmful pathogen adhesion.
Side effects
Overall, *Lactobacillus helveticus* R0052 is deemed safe for general consumption with no common side effects reported in studies. Rare adverse effects are not extensively documented. Caution is advised for individuals on certain medications like anti-epileptic drugs (e.g., valproate), as this may interfere with their bioavailability. Probiotics should be used judiciously by immunocompromised individuals until further studies clarify associated risks, though *L. helveticus* R0052 has not shown significant concerns.
Dosage
Recommended dosages for *Lactobacillus helveticus* R0052 typically lie between 1 and 4 billion CFU per day, with studies indicating effective doses at around 4 billion CFU in capsule form. It is recommended to take this probiotic twice daily after meals to improve gastrointestinal survival and efficacy. Although no explicit upper limits have been established, higher doses above 4 billion CFU have not been optimally studied. Proper storage is essential to maintain the strain’s viability and functionality.
FAQs
Is *Lactobacillus helveticus* R0052 safe?
Yes, it is generally considered safe, particularly for healthy individuals without immune deficiencies.
When should I take *Lactobacillus helveticus* R0052?
It is best taken after meals to optimize survival through the gastrointestinal system.
What benefits can I expect from this probiotic?
You may experience improved gut health, reduced AAD symptoms, enhanced immune response, and potential reductions in seizure susceptibility.
Can I use this as a replacement for medical treatment?
No, *L. helveticus* R0052 should be used as a supplementary adjunct, not a substitute for prescribed medical therapies.
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