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Kale Aerial Parts Extract

Also known as: Kale Aerial Parts Extract, Kale Extract, Leafy Greens Extract, Brassica oleracea Extract, Brassica oleracea var. acephala Extract

Overview

Kale Aerial Parts Extract is derived from the leaves of *Brassica oleracea* var. *acephala*, commonly known as kale. Kale is a nutrient-dense vegetable rich in vitamins, minerals, and phytochemicals, including glucosinolates, phenolics, and carotenoids. The extract is used for its potential health benefits, such as antioxidant, anti-inflammatory, and cardiovascular protective effects. It is available in various forms, including capsules, powders, and liquid extracts. While research is growing, most studies are observational or experimental, with limited human clinical trials. The primary sources of kale are cultivated farms, where it is grown for both food and extraction purposes. The extract aims to concentrate the beneficial compounds found in the whole vegetable.

Benefits

Kale extract is associated with several potential health benefits, though more research is needed to confirm these effects in humans. Animal studies suggest that kale extracts may improve lipid profiles by increasing HDL cholesterol and reducing triglycerides, potentially supporting cardiovascular health. The antioxidant properties of kale extracts have been demonstrated in vitro and in vivo, indicating a potential to reduce oxidative stress. Additionally, some evidence supports the anti-inflammatory effects of kale compounds, which may be beneficial in conditions like colitis. However, the strength of evidence for these benefits varies, and further human clinical trials are necessary to establish definitive conclusions.

How it works

Kale extract's mechanism of action is primarily attributed to its bioactive compounds. Glucosinolates are hydrolyzed into isothiocyanates, which exhibit anti-cancer and anti-inflammatory properties. Phenolic compounds act as antioxidants, neutralizing free radicals and reducing oxidative stress. Carotenoids also contribute to antioxidant activity and may protect against certain diseases. These compounds interact with various biological pathways, influencing cellular function and overall health. The combined effect of these compounds contributes to the observed health benefits, though the precise mechanisms are still under investigation.

Side effects

Kale extracts are generally considered safe for consumption, but high doses may lead to gastrointestinal upset, including bloating, gas, or diarrhea. Individuals with thyroid issues should exercise caution due to the potential goitrogenic effects of glucosinolates, which can interfere with thyroid hormone production. There is limited data on drug interactions, but it is advisable to consult with a healthcare provider before using kale extract, especially if taking medications that affect thyroid function or blood clotting. No severe adverse effects have been widely reported, but monitoring for any unusual symptoms is recommended. Pregnant or breastfeeding women should consult their healthcare provider before using kale extract.

Dosage

There is currently no established minimum effective dose for kale extracts, and optimal dosing ranges are not well-defined. Dosage recommendations vary widely depending on the concentration of bioactive compounds in the extract. Some studies have used doses equivalent to several servings of fresh kale, but these are not standardized. It is crucial to start with a low dose and gradually increase it while monitoring for any adverse effects. Due to the lack of standardized dosing guidelines, consulting with a healthcare professional is recommended to determine a safe and appropriate dosage based on individual health status and needs.

FAQs

Is kale extract safe to use?

Kale extract is generally safe, but high doses may cause gastrointestinal upset. Individuals with thyroid issues should be cautious due to potential goitrogenic effects. Consult a healthcare provider if you have concerns.

When is the best time to take kale extract?

There is no specific timing recommended for consumption. It can be taken with or without food. Consistency is key, so choose a time that fits your daily routine.

What benefits can I expect from taking kale extract?

Potential benefits include improved cardiovascular health and antioxidant activity. However, individual results may vary, and more research is needed to confirm these effects in humans.

Can kale extract interact with medications?

There is limited data on drug interactions, but it may interact with thyroid medications. Consult with a healthcare provider before use, especially if you are taking other medications.

Research Sources

https://www.mdpi.com/2223-7747/10/12/2629 – This review article discusses the health benefits of kale, including its antioxidant, anti-inflammatory, and anticancer properties. It highlights the role of kale's bioactive compounds, such as glucosinolates and flavonoids, in promoting overall health and preventing chronic diseases. The review emphasizes the need for more human clinical trials to confirm these benefits.
https://www.mdpi.com/2072-6643/15/6/1424 – This study investigates the impact of kale consumption on cardiovascular risk factors. It suggests that kale may improve lipid profiles and reduce oxidative stress, potentially lowering the risk of heart disease. The research highlights the importance of incorporating kale into a balanced diet for cardiovascular health.
https://onlinelibrary.wiley.com/doi/10.1002/jsfa.6251 – This research explores the neuroprotective effects of Tuscan Black Kale sprout extract in rats. The findings suggest that the extract may protect against neuronal damage and improve cognitive function. The study provides insights into the potential of kale as a neuroprotective agent.
https://pubmed.ncbi.nlm.nih.gov/32983422/ – This study investigates the impact of kale consumption on various health markers. The research suggests that kale may improve antioxidant status and reduce inflammation, contributing to overall well-being. The study highlights the potential of kale as a functional food for promoting health.
https://www.researchgate.net/publication/345239817_Kale_Nutritional_composition_and_antioxidant_properties – This paper provides an overview of the nutritional composition and antioxidant properties of kale. It details the various vitamins, minerals, and phytochemicals present in kale, as well as their potential health benefits. The paper emphasizes the role of kale as a nutrient-rich food with significant antioxidant capacity.