Igob 131
Also known as: WellTrim Ig, IGOB131, African mango extract, Irvingia gabonensis, Irvingia gabonensis extract (IGOB131)
Overview
WellTrim Ig (IGOB131) is a standardized extract derived from the seeds of the Irvingia gabonensis tree, native to West Africa. Widely recognized for its culinary and medicinal applications, this dietary supplement has gained prominence for weight management and enhancing metabolic and cardiovascular health. Classified as Generally Recognized As Safe (GRAS), WellTrim Ig is vegan-friendly and non-GMO. Research is moderate, with several clinical trials indicating significant benefits in weight loss and metabolic improvement. The extract is typically available in capsule and tablet forms, with particular focus on its ability to influence body weight and metabolic parameters favorably. However, caution is warranted due to possible manufacturer biases in some studies.
Benefits
Research indicates that WellTrim Ig can significantly reduce body weight, with studies reporting an average loss of 28 lbs over 10 weeks, a decrease in waist circumference by 6.7 inches, and a reduction in body fat of around 18.4%. Improvements in key metabolic markers have also been documented, notably a decrease in total cholesterol levels by 26.2%, LDL cholesterol by 27.2%, and better management of blood glucose levels. Overweight and obese populations benefit the most, experiencing enhanced appetite control and reduced inflammation. While many studies support these findings, variations in effect sizes underscore the necessity of individualized assessments when considering supplementation for weight management.
How it works
WellTrim Ig interacts with metabolic pathways primarily through regulation of hormones such as leptin and adiponectin, which are critical for energy balance and fat metabolism. The extract inhibits glycerol-3-phosphate dehydrogenase, an enzyme essential for fat production, and influences PPAR gamma, a receptor key to fat cell differentiation and metabolism. These actions collectively enhance the body's ability to regulate fat storage and promote metabolic health, although detailed investigations into the bioavailability of its bioactive components are still needed.
Side effects
WellTrim Ig is generally viewed as safe due to its natural origins, with minimal adverse effects reported. The lack of well-documented common side effects suggests a favorable tolerance among users. However, interactions with diabetes medications have been noted, necessitating caution for those under such treatments, as they may experience blood sugar fluctuations during supplementation. While there are no specific contraindications, pregnant or breastfeeding women are advised to consult healthcare providers prior to use. Continuous monitoring of blood sugar is recommended for diabetic patients to ensure balanced levels throughout the supplementation period.
Dosage
For effective results, the minimum recommended dosage of WellTrim Ig is 150 mg taken twice daily, with an optimal intake around 300 mg per day. Higher doses have not been established and could pose potential risks of adverse effects. It is advisable to consume the supplement 30-60 minutes before meals to enhance absorption. Common forms of delivery include capsules and tablets, and data suggest that taking it with food might improve bioavailability. Currently, specific cofactor requirements have not been identified.
FAQs
Can WellTrim Ig help with weight loss?
Yes, clinical studies have demonstrated significant weight loss and metabolic improvements with WellTrim Ig supplementation.
Is it safe to use WellTrim Ig with diabetes medications?
Caution is advised because WellTrim Ig may interact with blood sugar medications; monitoring blood sugar levels is essential.
What is the best time to take WellTrim Ig?
It is best taken 30-60 minutes before meals to enhance effectiveness and absorption.
How long before I can expect to see results?
Weight loss and metabolic improvements can typically be observed over a period of several weeks, particularly within the first 10 weeks.
Do I need to follow a special diet while using WellTrim Ig?
For optimal results, use WellTrim Ig in conjunction with a healthy diet and regular exercise.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332986/ – This meta-analysis assessed the efficacy of Irvingia gabonensis for weight loss, demonstrating significant reductions in body weight and waist circumference. The analysis included multiple studies, highlighting the variability of results attributed to sample size and potential biases.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150193/ – A clinical trial explored the impact of Irvingia gabonensis on body weight and metabolic parameters, confirming notable reductions in body fat and improved cholesterol levels. The study design favored rigorous controls, enhancing the reliability of the findings.