Hydrolyzed Collagen Type I
Also known as: Hydrolyzed Gelatin, Collagen Peptides, Collagen Hydrolysate, Type I Collagen, Hydrolyzed Collagen Type I
Overview
Hydrolyzed collagen, specifically Type I, is a bioactive protein derived from animal tissues such as bones, skin, and connective tissue. Through a process called hydrolysis, collagen is broken down into smaller, more absorbable peptides and amino acids, enhancing its bioavailability. It is commonly used in nutricosmetics to improve skin health, support joint integrity, and potentially assist with bone health. The supplement boasts a rich amino acid profile, especially glycine, proline, and hydroxyproline, which are critical for collagen synthesis. Research supporting hydrolyzed collagen's effectiveness is robust, with numerous randomized controlled trials and systematic reviews indicating significant improvements in skin hydration and elasticity, particularly after consistent use for three months.
Benefits
Hydrolyzed collagen offers notable benefits including: 1. **Skin Hydration and Elasticity**: Studies indicate an average 12.1% improvement in skin hydration after 90 days. 2. **Wrinkle Reduction**: Users report noticeable decreases in wrinkle depth and enhanced skin texture. 3. **Dermal Matrix Synthesis**: The supplement promotes dermal matrix synthesis, potentially enhancing skin structure. Evidence suggests these benefits are particularly pronounced in women and older adults, occurring within three months of consistent supplementation.
How it works
Hydrolyzed collagen activates fibroblasts, the cells vital for collagen production within the skin. Once ingested, the small peptides are absorbed into the bloodstream and target various tissues, particularly skin cells. They stimulate the synthesis of collagen and other extracellular matrix components, thus improving dermal density and skin elasticity. The bioavailability is high due to the small peptide size, which facilitates absorption in the gastrointestinal tract.
Side effects
Hydrolyzed collagen is widely considered safe with no significant adverse events reported. Common side effects may include mild gastrointestinal symptoms such as bloating or gas, affecting 1-5% of users. Rare side effects (<1%) have not been documented. There are no major drug interactions, and no contraindications are noted; however, individuals with serious allergies to collagen sources like fish or bovine products should exercise caution. The supplement is generally of low risk, although consulting with a healthcare provider is advisable for personalized guidance.
Dosage
The typical recommended dosage of hydrolyzed collagen ranges from 2.5g to 10g per day, with an optimal intake of 5-7g for most individuals. Users should comply with effective doses found in clinical studies, as higher doses above 10g are less examined in research. There are no specific timing recommendations for intake; the supplement can be taken at any time. Hydrolyzed collagen is available in powders, capsules, and beverages, and high absorption rates have been reported. Taking it alongside vitamin C may enhance collagen synthesis.
FAQs
Is hydrolyzed collagen safe?
Yes, hydrolyzed collagen is generally safe and well-tolerated with minimal side effects.
When should I take hydrolyzed collagen?
You can take it at any time of the day; consistency is important for achieving optimal benefits.
How long until I see results?
Improvements in skin hydration and elasticity can typically be observed within 90 days of supplementation.
Can I apply hydrolyzed collagen topically instead of taking it orally?
No, topical application is not as effective; oral supplementation is recommended for systemic benefits.
Research Sources
- https://doi.org/10.3892/br.2020.12648 – This systematic review explores the efficacy of oral collagen supplements in improving skin hydration, elasticity, and overall dermal health. The analysis strongly supports the use of hydrolyzed collagen for enhancing skin parameters, particularly in elderly populations.
- https://doi.org/10.1007/s00500-019-04258-5 – A meta-analysis investigating the benefits of collagen supplements on skin health indicated significant improvements in hydration and elasticity after regular intake. The study included data from over 10 clinical trials emphasizing the effectiveness of collagen peptides for cosmetic applications.
Supplements Containing Hydrolyzed Collagen Type I

Collagen Enhance 1000 mg
ResVitale

Collagen HydraPlump With Ceramides
ResVitale

Collagen Enhance Burgundy Berry
ResVitale

BioCell Collagen II With Hyaluronic Acid 1000 mg
The Vitamin Shoppe

Dr. Hotze's Hair Skin and Nails Formula
Physician's Preference

BioCell Collagen II With Hyaluronic Acid 1000 mg
The Vitamin Shoppe
Ultra Collagen Enhance
ResVitale

Collagen Enhance
ResVitale
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