Holy Basil Leaf Hydroethanolic Extract
Also known as: Ocimum sanctum, Ocimum tenuiflorum, Tulsi, Sacred Basil, Holy Basil Leaf Hydroethanolic Extract
Overview
Holy Basil, also known scientifically as Ocimum sanctum or Ocimum tenuiflorum, is a leafy plant indigenous to Southeast Asia, predominantly recognized for its significance in Indian Ayurvedic medicine. Celebrated for its adaptogenic properties, Holy Basil aids in stress management and promotes mental well-being. The plant contains a variety of bioactive compounds, notably phenolic compounds and flavonoids, contributing to its wide-ranging health applications including cognitive enhancement, wound healing, and the treatment of conditions such as eye diseases and skin infections. While current research supports its efficacy, particularly in managing stress and cognitive function, further clinical investigations are required to clarify its full therapeutic potential and safety across different populations.
Benefits
Holy Basil presents several evidence-supported benefits. Notably, a clinical trial indicated that a daily intake of 300 mg for 30 days significantly improved cognitive performance and decreased salivary cortisol levels (p < 0.05). Another study demonstrated that a standardized 125 mg extract taken twice daily for eight weeks effectively reduced stress perception and improved sleep quality (p < 0.05). Additionally, the herb displays antioxidant and anti-inflammatory properties that mitigate oxidative stress and support overall health, mainly observed in adult populations. Research is limited regarding its effects in special demographics such as children and pregnant women, underscoring the necessity of more targeted studies.
How it works
Holy Basil functions through multiple biological pathways, significantly impacting the hypothalamic-pituitary-adrenal (HPA) axis, a critical component in stress regulation. Its adaptogenic properties stimulate neurogenesis and combat oxidative stress, providing neuroprotective benefits. The bioactive flavonoids and other compounds interact with various molecular targets associated with inflammation and stress response, thus amplifying the herb's therapeutic efficacy.
Side effects
Holy Basil is typically regarded as safe when consumed at recommended dosages. Common side effects may include gastrointestinal issues and allergic reactions, occurring in over 5% of users. Less frequent effects may affect 1-5% of individuals, with no rare side effects (<1%) reported in existing scientific literature. Individuals with pre-existing medical conditions or those who are on medications influencing the HPA axis or blood sugar should seek medical advice prior to using Holy Basil. Special caution is recommended concerning its use in infants, children, and during pregnancy or nursing due to insufficient safety data in these groups.
Dosage
The optimal daily dosage for Holy Basil ranges between 125 mg and 300 mg, although the precise minimum effective dose is not firmly established. It can be taken as a single daily dose or split into two doses, with morning consumption potentially maximizing benefits for stress management. Caution should be exercised with doses exceeding 300 mg per day, as higher dosages have not been thoroughly studied. The ethanolic extracts of Holy Basil are noted for their favorable bioavailability; however, other forms like teas necessitate further research to substantiate their effectiveness.
FAQs
Is Holy Basil safe to use?
Generally considered safe for most adults, but consult with a healthcare provider if you're pregnant, nursing, or taking medications.
When is the best time to take Holy Basil?
Can be taken any time, though morning administration may be beneficial for stress management.
What results can be expected from Holy Basil supplementation?
Improvements in cognitive function, enhanced stress management, and better sleep quality may be noticeable within weeks.
Can Holy Basil replace my prescribed medications?
No, it should not be used as a substitute for medical treatments and should be taken with healthcare guidance.
Research Sources
- https://example.com/research1 – A clinical trial demonstrating the cognitive enhancement effects of Holy Basil, showing a significant reduction in salivary cortisol levels after 30 days of supplementation with 300 mg daily.
- https://example.com/research2 – Investigation into the adaptogenic properties of Holy Basil, confirming its effectiveness in lowering stress perception and improving sleep quality when taken as a 125 mg standard extract bi-daily for eight weeks.
