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Hemp Extract Aerial Parts

Also known as: Hemp Extract, Cannabis sativa, Hemp, Cannabis, Cannabis sativa L. (Hemp Extract Aerial Parts)

Overview

Hemp extract aerial parts are derived from the aerial parts of the *Cannabis sativa* plant, commonly known as hemp. These extracts contain a variety of bioactive compounds, most notably cannabinoids like cannabidiol (CBD), as well as terpenes and other phytochemicals. Hemp extract is primarily used for its potential therapeutic effects, including stress relief and epilepsy treatment. The extract interacts with the body's endocannabinoid system, influencing neurotransmitter release and modulating immune responses. It is available in various forms, including oils, capsules, and topical creams. Research on hemp extract is growing, with systematic reviews and meta-analyses providing insights into its safety and efficacy. The quality of available evidence is moderate, with increasing support for its use in specific conditions.

Benefits

Hemp extract, particularly its CBD component, has demonstrated efficacy in reducing seizure frequency in certain types of epilepsy. Studies have shown significant reductions in seizure frequency with CBD treatment [1]. Additionally, some research suggests that hemp extract may provide stress relief, although more studies are needed to confirm this effect [2]. Potential benefits for anxiety and sleep have also been reported, but the evidence is less robust. Hemp extract may be particularly beneficial for individuals with epilepsy or those seeking stress relief. Effect sizes vary, but clinically significant reductions in seizure frequency have been observed in epilepsy studies. Benefits may be observed within weeks of use, depending on the condition being treated.

How it works

Hemp extract primarily interacts with the endocannabinoid system (ECS), a complex network of receptors, enzymes, and endocannabinoids that regulate various physiological processes. The main cannabinoids in hemp extract, such as CBD, influence neurotransmitter release and modulate immune responses. While CBD has a low affinity for CB1 and CB2 receptors, it may act through other mechanisms, such as influencing the activity of other receptors and enzymes in the ECS. This interaction affects the nervous and immune systems, contributing to its potential therapeutic effects. The bioavailability of hemp extract varies depending on the method of administration, with sublingual absorption generally being more effective than oral ingestion.

Side effects

Hemp extract is generally considered safe, with few serious adverse effects reported [1]. Common side effects include fatigue, diarrhea, and changes in appetite. Uncommon side effects may include dizziness and nausea. Severe allergic reactions are rare. Hemp extract may interact with certain medications, such as blood thinners, potentially altering their effects. It is contraindicated in pregnancy and breastfeeding due to insufficient safety data. Caution is advised in children and individuals with liver or kidney disease. It's important to monitor for side effects and consult with a healthcare professional before using hemp extract, especially if taking other medications or having pre-existing health conditions.

Dosage

The minimum effective dose of hemp extract varies by condition. For epilepsy, doses often start at 2.5 mg/kg/day, with optimal dosage ranges typically between 5-20 mg/kg/day. The maximum safe dose is not well established, and caution is advised beyond 20 mg/kg/day. Consistent dosing is recommended. Sublingual administration may enhance bioavailability. Food intake can affect absorption. Start with low doses and adjust as needed, under the guidance of a healthcare professional. Individual responses can vary, so it's important to monitor for effects and adjust the dosage accordingly.

FAQs

How should I start using hemp extract?

Start with a low dose and gradually increase it as needed, while monitoring for any side effects. Consult with a healthcare professional for personalized guidance.

Is hemp extract safe?

Hemp extract is generally considered safe, but it can cause side effects like fatigue or diarrhea. Monitor for any adverse reactions and consult with a healthcare professional if needed.

How often should I take hemp extract?

Consistent dosing is key. Follow the recommendations of your healthcare provider or the product label for timing and frequency of administration.

What results can I expect from using hemp extract?

Results vary depending on the condition being treated. It is not psychoactive like THC and may not provide immediate effects. Be patient and consistent with dosing.

Will hemp extract make me high?

No, hemp extract is not psychoactive like THC. It will not produce a 'high' sensation. It primarily contains CBD, which does not have intoxicating effects.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC7608221/ – This systematic review and meta-analysis examined the efficacy and tolerability of CBD in treating epilepsy. The study found that CBD is well-tolerated and effective in reducing seizures in certain epilepsy types, highlighting its potential as a therapeutic option for individuals with epilepsy. The review noted heterogeneity in study designs and dosages as limitations.
https://karger.com/mca/article/6/1/138/869446/Effects-of-Two-Cannabidiol-Oil-Products-on-Self – This randomized controlled trial investigated the effects of two cannabidiol oil products on self-reported stress and anxiety. The study found that hemp extract may provide stress relief, although more research is needed to confirm this effect. The limitations included small sample sizes and variable dosing regimens.
https://www.mdpi.com/1420-3049/30/9/1947 – This analytical study focused on the chemical composition of hemp extracts, identifying a variety of bioactive compounds, including cannabinoids and terpenes. The study provides valuable insights into the complex chemical profile of hemp extracts. The study focuses on chemical composition rather than clinical effects.
https://www.mdpi.com/2297-8739/8/10/183 – This review discusses the potential therapeutic applications of hemp-derived compounds, focusing on their mechanisms of action and clinical evidence. The review highlights the diverse range of potential benefits associated with hemp extracts. The review provides a broad overview of the therapeutic potential of hemp-derived compounds.
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.892314/full – This study investigates the impact of hemp seed supplementation on various health markers, including lipid profiles and inflammatory markers. The study provides insights into the potential nutritional benefits of hemp seeds. The study focuses on hemp seeds rather than hemp extract aerial parts.