Hemo Pump Blend
Also known as: Hemo Pump Blend, Proprietary Nitric Oxide Booster, Muscle Pump Enhancer
Overview
Hemo Pump Blend is a proprietary supplement formulation designed to optimize muscle 'pump' during physical activity by enhancing blood flow and cellular hydration. Typically composed of L-citrulline, glycerol, and Amla (Phyllanthus emblica) fruit extract, this blend aims to improve muscular endurance, facilitate vasodilation, and increase muscle fullness. L-citrulline, a non-essential amino acid found in watermelon, is a precursor to nitric oxide, which is crucial for vasodilation. Glycerol, a sugar alcohol, acts as an osmolyte to enhance cellular and plasma volume, contributing to hydration. Amla extract, derived from Indian gooseberry, provides antioxidant support. While direct research on the specific 'Hemo Pump Blend' is limited, the efficacy and safety of its individual components are supported by a moderate body of research, primarily from small randomized controlled trials and mechanistic studies. It is commonly used as a pre-workout supplement.
Benefits
The benefits of Hemo Pump Blend are primarily derived from its key ingredients. L-citrulline is well-researched for its ability to increase plasma arginine and nitric oxide production, leading to vasodilation and improved blood flow. Meta-analyses indicate that L-citrulline supplementation can significantly improve muscular endurance and reduce fatigue during high-intensity exercise, with studies showing moderate improvements (e.g., 10-15% increase in reps to failure). Glycerol acts as an osmolyte, enhancing cellular hydration and plasma volume, which may improve endurance performance and mitigate dehydration effects during prolonged exercise. Amla extract contributes antioxidant and anti-inflammatory effects, potentially supporting recovery and reducing exercise-induced oxidative stress. The combination of these ingredients is hypothesized to provide synergistic benefits for muscle pump, performance, and recovery. Acute ingestion 30-60 minutes before exercise is typical for performance effects.
How it works
Hemo Pump Blend operates through the synergistic actions of its primary components. L-citrulline is absorbed and then converted to L-arginine in the kidneys. L-arginine serves as a substrate for endothelial nitric oxide synthase (eNOS), leading to increased nitric oxide (NO) synthesis. NO is a potent vasodilator, relaxing blood vessels and increasing blood flow to working muscles, which enhances nutrient and oxygen delivery and contributes to the 'pump' sensation. Glycerol, upon ingestion, is rapidly absorbed and distributed throughout the body, increasing intracellular and extracellular fluid volume. This hyperhydration effect improves muscle fullness and can support endurance by optimizing fluid balance. Amla extract, rich in antioxidant polyphenols, works by scavenging free radicals, thereby reducing oxidative damage and inflammation that can occur during intense exercise. The combined effect aims to optimize blood flow, hydration, and cellular protection for enhanced athletic performance.
Side effects
Hemo Pump Blend is generally considered safe when consumed at recommended dosages. The most commonly reported side effects are mild gastrointestinal discomfort, which can occur with higher doses of L-citrulline or glycerol. These may include stomach upset, bloating, or diarrhea. Due to its vasodilatory effects, caution is advised for individuals with hypotension (low blood pressure) or pre-existing cardiovascular instability, as the blend could potentially exacerbate these conditions. While minimal drug interactions are known, individuals taking nitrates or blood pressure medications should consult a healthcare professional, as the combined vasodilatory effects could lead to an excessive drop in blood pressure. There is limited data on the use of Hemo Pump Blend in special populations, such as pregnant or nursing women, who should therefore seek medical advice before use. Overall, adverse events are infrequent and typically mild.
Dosage
For optimal performance enhancement, the typical effective dose of L-citrulline, a primary component, ranges from 3 to 6 grams per day. Glycerol is often included in blends at lower doses, typically around 1-2 grams, though hyperhydration protocols may use higher amounts (1-1.5 g/kg body weight). Amla extract doses commonly range from 300-500 mg, particularly for standardized extracts. For acute effects, it is recommended to ingest Hemo Pump Blend approximately 30-60 minutes prior to exercise. The blend is commonly available in powder form, designed to be mixed with water. It is important to adhere to the manufacturer's specific dosing instructions for the proprietary blend, as the exact ratios of ingredients can vary. There are no established upper limits for the blend as a whole, but individual ingredient safety thresholds should be considered.
FAQs
Is Hemo Pump Blend effective for muscle pump?
Yes, evidence supports that its key ingredients, L-citrulline and glycerol, improve blood flow and hydration, contributing to enhanced muscle pump sensations during exercise.
Is Hemo Pump Blend safe to use?
Generally, Hemo Pump Blend is considered safe at recommended doses. Mild gastrointestinal side effects are possible, especially with higher intake. Consult a healthcare provider if you have underlying health conditions or are on medication.
When is the best time to take Hemo Pump Blend?
For acute performance benefits, it is recommended to take Hemo Pump Blend approximately 30-60 minutes before your workout.
How quickly can I expect to see results from Hemo Pump Blend?
Acute effects on blood flow, muscle fullness, and exercise endurance can typically be experienced within one hour of ingestion.
Research Sources
- https://www.journalofexerciseandnutrition.com/index.php/JEN/article/view/144 – This study investigated the effects of a blend containing L-citrulline, glycerol, and Amla extract (3DPump) on muscular endurance and hydration markers. It found that the blend showed improvements similar to L-citrulline alone, suggesting potential additive effects of glycerol and Amla on muscle pump and recovery. The study was a small RCT with a crossover design, indicating preliminary but promising results.
- https://pubmed.ncbi.nlm.nih.gov/31401022/ – This meta-analysis on L-citrulline supplementation synthesized findings from multiple randomized controlled trials. It concluded that citrulline supplementation (3-6 g/day) significantly improves exercise performance by increasing nitric oxide availability, reducing fatigue, and enhancing blood flow. The review highlighted moderate effect sizes for endurance improvements and a favorable safety profile.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11989519/ – This article discusses the physiological mechanisms of glycerol as an osmolyte. It explains how glycerol ingestion increases total body water and plasma volume, which can improve endurance performance, especially in hot environments, and reduce the risk of dehydration. While typical doses for hyperhydration are higher than those in blends, even lower doses contribute to hydration status.
Recommended Articles

2025's Top Vegan Protein Powders: A Buyer's Guide
In 2025, the best vegan protein powders are third-party tested, ensuring purity, safety, and high nutritional content.

L-Theanine Dosage for Focus: Avoid Drowsiness
200-400mg daily of L-theanine enhances focus without causing drowsiness, with benefits amplified when combined with caffeine.

Bone Health Supplements for Plant-Based Postmenopausal Women
Optimal bone health for postmenopausal individuals on plant-based diets involves calcium, vitamin D, magnesium, and vitamin K2 supplementation.

Best Eye Health Ingredients: Vision Supplements Guide
Vitamins C and E, lutein, zeaxanthin, zinc, and omega-3s are crucial for reducing the risk of eye diseases like macular degeneration.